Clinical trials (12 193)

assignment

scheduleNot Yet RecruitingIPhase I

Phase 1/2 Open‑Label Study of VS‑7375, a KRAS G12D (ON/OFF) Inhibitor, as Monotherapy and Combination Therapy in Patients with Advanced KRAS G12D‑Mutant Solid Tumors

A Coruna Galicia, Spain

Countries

Interventions

Carboplatin

Sponsors

Verastem Inc.

assignment

scheduleNot Yet RecruitingIIPhase II

Randomized, Double‑Blind, Placebo‑Controlled Dose‑Ranging and Efficacy Study of Oral SIR9900 in Adults with VEXAS Syndrome

Ancona, Italy

Countries

Sponsors

Sironax USA Inc.

assignment

scheduleNot Yet RecruitingIPhase I

Phase I Randomized, Double‑Blind, Placebo‑Controlled Study of Inhaled RO7616605 Assessing Safety and Activity in Healthy Volunteers and COPD Patients

Berlin, Germany

Countries

Sponsors

Genentech Inc.

assignment

scheduleNot Yet RecruitingIIIPhase III

Phase 3 Randomized Trial of Teclistamab + Talquetamab Combination vs Daratumumab + Lenalidomide Maintenance in MRD‑Positive Newly Diagnosed Multiple Myeloma Post‑ASCT

Bydgoszcz, Poland

Countries

Interventions

Daratumumab

Sponsors

Polish Myeloma Consortium

assignment

scheduleNot Yet RecruitingIIPhase II

Phase II Study of Total Neoadjuvant Durvalumab Plus FLOT Combination Therapy Followed by Postoperative Durvalumab in Resectable Gastroesophageal Adenocarcinoma

Badalona, Spain

Countries

Interventions

Calcium Folinate

Sponsors

Frankfurter Institut Fuer Klinische Krebsforschung IKF GmbH

assignment

scheduleNot Yet RecruitingIIIPhase III

Evaluation of Contraceptive Efficacy, Safety and Tolerability of Oral Drospirenone 4 mg (LPRI‑CF113) Over 13 Cycles: Multicentre Open‑Label Single‑Arm Study

Barcelona, Spain

Countries

Interventions

DROSPIRENONE

Sponsors

Chemo Research S.L.

assignment

scheduleNot Yet RecruitingIPhase I

A Randomized Controlled Trial of Autologous Immune Cell Therapy in Patients with Newly Diagnosed Highly Active Multiple Sclerosis

Hanover, Germany

Countries

Sponsors

Medizinische Hochschule Hannover

assignment

scheduleNot Yet RecruitingIIPhase II

Phase II Study of 99mTc‑NTP15‑5 SPECT Imaging for Detection of Hand Joint Pathology in Digital Osteoarthritis and Rheumatoid Arthritis

Clermont-Ferrand, France

Countries

Sponsors

Centre Jean Perrin

assignment

scheduleNot Yet RecruitingIIIPhase III

Phase III Randomized Double‑Blind Placebo‑Controlled Trial of Elecoglipron (AZD5004) on Renal Decline and Mortality in Adults with Chronic Kidney Disease

Aalborg, Denmark

Countries

Interventions

Azd5004

Sponsors

AstraZeneca AB

assignment

scheduleNot Yet RecruitingIIIPhase III

Phase 3 Open‑Label Study of Intrathecal BIIB115 in Patients Aged 15–60 Years with Spinal Muscular Atrophy, Treatment‑Naïve or Previously Treated with Risdiplam

Dublin, Ireland

Countries

Interventions

BIIB115

Sponsors

Biogen Idec Research Limited

assignment

scheduleNot Yet RecruitingIPhase I

Phase II Study of 161Tb‑Labeled Gastrin Analogue for Precision Therapy in Patients with Advanced Medullary Thyroid Cancer

Gliwice, Poland

Countries

Sponsors

Uniwersytet Jagiellonski Collegium Medicum

assignment

scheduleNot Yet RecruitingIIPhase II

De‑escalation of Neoadjuvant Carboplatin‑Paclitaxel Plus Pembrolizumab in Stage II Triple‑Negative Breast Cancer with High Tumor‑Infiltrating Lymphocytes

Avignon, France

Countries

Interventions

Carboplatin

Sponsors

Institut Paoli Calmettes

assignment

scheduleNot Yet RecruitingIIPhase II

Randomized active-controlled trial of safety and pharmacodynamics of two blinded doses of RBD4059 (vortosiran) versus apixaban in non-valvular atrial fibrillation

Danderyd, Sweden

Countries

Interventions

Apixaban

Sponsors

Ribocure Pharmaceuticals AB

assignment

scheduleNot Yet RecruitingIIPhase II

Botulinum toxin type A for refractory upper‑limb resting tremor in Parkinson’s disease: a double‑blind, placebo‑controlled crossover trial

Nîmes, France

Countries

Interventions

Botulinum Toxin Type A - Haemagglutinin Complex

Sponsors

Centre Hospitalier Universitaire De Toulouse

assignment

scheduleNot Yet RecruitingIIIPhase III

VATS versus Intrapleural Alteplase/Dornase Alfa Enzymatic Therapy for Parapneumonic Pleural Infection (Empyema) in Patients Unresponsive to Antibiotics and Chest Tube Drainage

Alkmaar, The Netherlands

Countries

Interventions

Alteplase

Sponsors

Amsterdam UMC Stichting

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Clinical trials (12 193)

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Clinical trials (12 193)