UZ Leuven

Address
Herestraat 49

Sponsor Overview

assignment
75
sponsored trials
science
118
molecules
location_city
142
research centres
public
6
countries
person_search
294
investigators

Specializations

Gastroenterology and Inflammatory Bowel Disease

Research activity includes Crohn’s disease, acute severe ulcerative colitis, pouchitis, short bowel syndrome, irritable bowel syndrome, functional dyspepsia, gastro-oesophageal reflux disease, and opioid-induced constipation.

  • Inflammatory bowel disease surgery and recurrence
  • Intestinal motility and upper gastrointestinal symptoms
  • Supportive care in gastrointestinal disorders

Additional work spans infliximab treatment strategies, proton pump inhibitor deprescribing, and symptom-focused care in chronic digestive disease.

Oncology and Hematologic Malignancy

The oncology portfolio covers gastro-esophageal adenocarcinoma, pancreatic ductal adenocarcinoma, colorectal cancer, rectal cancer, breast cancer, prostate cancer, ovarian cancer, and malignant melanoma.

  • Targeted treatment in receptor-defined cancers
  • Metastasis-directed approaches in advanced solid tumors
  • Perioperative and neoadjuvant cancer care

Studies also address febrile neutropenia, tumor imaging with PET/CT, and treatment selection in clinically challenging oncologic settings.

Neurology, Neurodegeneration, and Developmental Disorders

Clinical research includes Alzheimer disease, frontotemporal dementia, Lewy body disease, Parkinson’s disease, multiple system atrophy, amyotrophic lateral sclerosis, spinal muscular atrophy, autism spectrum disorder, cerebral palsy, traumatic brain injury, and drug-resistant epilepsy.

  • Neurodegenerative disease characterization
  • Motor and cognitive outcome assessment
  • Pediatric neurodevelopmental care

Imaging and biomarker work extends to tau pathology, carotid atherosclerosis, and functional brain circuit studies.

Rheumatology, Dermatology, and Immune-Mediated Disease

Studies focus on rheumatoid arthritis, psoriatic arthritis, axial spondyloarthritis, giant cell arteritis, IgG4-related disease, hidradenitis suppurativa, chronic rhinosinusitis with nasal polyps, and nonsteroidal anti-inflammatory drug-exacerbated respiratory disease.

  • Biologic and targeted immune therapy
  • Vasculitis and inflammatory airway disease
  • Inflammatory skin and joint disorders

Research also addresses dupilumab, rituximab, tofacitinib, and anti-TNF strategies in immune-mediated conditions.

Perioperative Care, Critical Care, and Clinical Pharmacology

Trials span infective endocarditis, severe community-acquired pneumonia, prosthetic joint infections, fracture-related infections, cardiac surgery, obstetric and fetal surgery, and intensive care management in critically ill patients.

  • Antimicrobial treatment optimization
  • Perioperative analgesia and anesthesia
  • Drug exposure and pharmacokinetics in complex care

Additional interests include ceftazidime-avibactam, clindamycin, apixaban, ketamine, oxytocin, and naloxegol.

Sponsored Trials

Trial Name Country Status
A multicenter uncontrolled, open label, prospective non-comparative single arm phase II study with bicalutamide (an antiandrogen) in combination with abemaciclib (an oral CDK 4/6 inhibitor) in 4 cohorts of locoregionally advanced inoperable or metastatic AR positive triple-negative breast cancer (AR+ TNBC).Belgium BelgiumRecruiting
A Randomized, Double-Blind, Placebo-Controlled Crossover Study of Clebopride Hydrogen Maleate in Patients with Rumination SyndromeBelgium BelgiumRecruiting
Bisoprolol Effects on Quality of Life and Cardiac Rehabilitation Outcomes in Post-Myocardial Infarction Patients with Preserved Ejection FractionBelgium BelgiumRecruiting
Comparative Diagnostic Efficacy of [18F]AlF-FAPI-74 Versus [18F]FDG PET/CT in Fever of Unknown Origin, IgG4-Related Disease, and Axial SpondyloarthritisBelgium BelgiumRecruiting
Comparative Evaluation of Cardiac [18F]-MFBG PET and [123I]-MIBG SPECT in Differentiating Parkinson's Disease, Multiple System Atrophy, Dementia with Lewy Bodies, and Alzheimer's DiseaseBelgium BelgiumRecruiting
Comparative Study of Preservative-Free vs. Preserved Dexamethasone and Diclofenac Eye Drops Post-Cataract SurgeryBelgium BelgiumNot Recruiting
Congenital CMV treated with valaciclovir during pregnancy: a prospective cohort studyBelgium BelgiumNot Recruiting
Determining the optimal strategy for stopping chronic proton pump inhibitor therapy in primary care patients: impact of on-demand use, adjustment of therapy or discontinuation.Belgium BelgiumNot Recruiting
Diagnostic Accuracy of [18F]AlF‑FAPI‑74 PET/CT for Detecting Deep Infiltrating and Superficial Peritoneal Endometriosis in Suspected PatientsBelgium BelgiumNot Yet Recruiting
Efficacy of Bilateral Superficial Parasternal Intercostal Plane Block with Ropivacaine Hydrochloride in Postoperative Recovery of Cardiac Surgery PatientsBelgium BelgiumRecruiting
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Data & Insights

science
Molecule Portfolio
Compounds under investigation
12
Exclusive Molecules
out of 118 total (10% not shared with other sponsors)

This sponsor works with 118 molecules, of which 12 are not being studied by other sponsors.

hub
Site Partnerships
Collaboration with research centres
20%
Return partnership rate
29 of 142 sites collaborated multiple times

This sponsor has worked with 142 sites across their trial portfolio.

Therapeutic Focus

  • 1.
    Digestive System Diseases14 trials
    280 other sponsors
  • 2.
    Neoplasms8 trials
    853 other sponsors
  • 3.
    Bacterial Infections and Mycoses6 trials
    180 other sponsors
  • 4.
    Cardiovascular Diseases6 trials
    359 other sponsors
  • 5.
    Musculoskeletal Diseases6 trials
    238 other sponsors
  • 6.
    Nervous System Diseases6 trials
    449 other sponsors
  • 7.
    Nutritional and Metabolic Diseases5 trials
    211 other sponsors
  • 8.
    Physiological processes5 trials
    28 other sponsors
  • 9.
    Psychological Phenomena5 trials
    20 other sponsors
  • 10.
    Anesthesia and Analgesia4 trials
    100 other sponsors
  • 11.
    Behavior and Behavior Mechanisms4 trials
    38 other sponsors
  • 12.
    Immune System Diseases4 trials
    322 other sponsors
  • 13.
    Therapeutics4 trials
    87 other sponsors
  • 14.
    Diagnosis3 trials
    83 other sponsors
  • 15.
    Female Urogenital Diseases and Pregnancy Complications3 trials
    142 other sponsors
  • 16.
    Behavioral Disciplines and Activities2 trials
    20 other sponsors
  • 17.
    Digestive System and Oral Physiological Phenomena2 trials
    16 other sponsors
  • 18.
    Investigative Techniques2 trials
    35 other sponsors
  • 19.
    Male Urogenital Diseases2 trials
    111 other sponsors
  • 20.
    Otorhinolaryngologic Diseases2 trials
    49 other sponsors
  • 21.
    Pathological Conditions, Signs and Symptoms2 trials
    91 other sponsors
  • 22.
    Skin and Connective Tissue Diseases2 trials
    247 other sponsors
  • 23.
    Congenital, Hereditary, and Neonatal Diseases and Abnormalities1 trial
    165 other sponsors
  • 24.
    Equipment and Supplies1 trial
    2 other sponsors
  • 25.
    Eye Diseases1 trial
    138 other sponsors
  • 26.
    Microbiological Phenomena1 trial
    9 other sponsors
  • 27.
    Not possible to specify1 trial
    220 other sponsors
  • 28.
    Virus Diseases1 trial
    182 other sponsors

Partnered Research Centres

142 centres
location_city
assignment26
Algemeen Stedelijk Ziekenhuis Campus Aalst
Address
Merestraat 80, 9300 Aalst
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location_city
assignment25
Algemeen Ziekenhuis Damiaan Oostende
Address
Gouwelozestraat 100, 8400 Ostend
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location_city
assignment283
Algemeen Ziekenhuis Delta
Address
Deltalaan 1, 8800 Roeselare
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location_city
assignment163
Algemeen Ziekenhuis Groeninge
Address
President Kennedylaan 4, 8500 Kortrijk
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location_city
assignment1
Algemeen Ziekenhuis Jan Portaels
Address
Gendarmeriestraat 65, 1800 Vilvoorde
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location_city
assignment61
Algemeen Ziekenhuis Klina
Address
Augustijnslei 100, 2930 Brasschaat
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