Miriam L.
- Country
- Spain
- Department
- Oncology
Research Overview
- Phase 3 Randomized Study of INCB161734 Plus Combination Chemotherapy Versus Placebo Plus Chemotherapy in KRAS G12D‑Mutated Metastatic Pancreatic Ductal Adenocarcinoma
- Evaluation of Atezolizumab and Digital Health Solutions on Health Outcomes in Metastatic and Early-Stage Lung and Hepatocellular Carcinomas
- Phase IIb Open-label Randomized Study of Nab-Paclitaxel, Gemcitabine, and VCN-01 in Metastatic Pancreatic Cancer Patients
Data & Insights
Has run more than one trial at 21 of 123 partner sites.
Specializations
Thoracic and Gastrointestinal Oncology
Clinical activity includes non-small cell lung cancer, small cell lung cancer, colorectal cancer, gastroesophageal junction adenocarcinoma, and hepatocellular carcinoma, with interest in advanced, resectable, and metastatic disease settings.
- Non-small cell lung cancer
- Colorectal cancer
- Hepatocellular carcinoma
- Gastric cancer
Therapeutic focus extends to KRAS G12C-mutant disease, MSI-H/dMMR tumors, and combination strategies in solid tumors.
Breast, Melanoma, and Head & Neck Cancer
Research involvement spans breast cancer subtypes, melanoma, and head and neck squamous cell carcinoma, including recurrent, metastatic, and high-risk localized disease.
- Breast cancer
- Melanoma
- Head and neck squamous cell carcinoma
- Uveal melanoma
The portfolio also includes HER2-positive, HR-positive/HER2-negative, and triple-negative breast cancer, with attention to immunotherapy and targeted treatment options.
Dermatology and Immune-Mediated Disease
Active interest is seen in atopic dermatitis, psoriasis, hidradenitis suppurativa, alopecia areata, and cutaneous lupus erythematosus, reflecting a broad dermatologic and inflammatory disease profile.
- Atopic dermatitis
- Plaque psoriasis
- Hidradenitis suppurativa
- Alopecia areata
Additional interest covers psoriatic arthritis, systemic lupus erythematosus, and vitiligo, linking dermatology with immune-mediated care.
Hepatic, Viral, and Metabolic Disorders
Clinical research includes non-alcoholic steatohepatitis, alcohol-related liver disease, chronic hepatitis B, hepatitis C virus infection, and hepatitis D virus infection.
- Non-alcoholic steatohepatitis
- Chronic hepatitis B
- Hepatitis C virus infection
- Alcohol-related liver disease
Metabolic interests also include obesity, overweight, type 2 diabetes mellitus, and hypoparathyroidism.
Cardiovascular, Ophthalmic, and Infectious Disease
Further activity covers atherosclerotic cardiovascular disease, atrial fibrillation, heart failure, and transcatheter aortic valve implantation-related care, alongside diabetic retinopathy, age-related macular degeneration, and retinal vein occlusion.
- Atherosclerotic cardiovascular disease
- Heart failure
- Diabetic retinopathy
- HIV infection
Infectious disease work also includes tuberculosis, severe influenza, and community-acquired pneumonia, with additional attention to stroke prevention and venous thromboembolism.
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