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Hospital General Universitario De Valencia

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Cardiovascular Diseases

Hospital General Universitario De Valencia is investigating novel anticoagulation strategies for atrial fibrillation, aiming to lower the risk of stroke and systemic embolism through a direct comparison of new agents with established therapy.

  • Atrial fibrillation management
  • Prevention of cardioembolic events
  • Evaluation of alternative anticoagulants
  • Stroke risk reduction outcomes

Across its portfolio of 13 trials, the site engages 72 investigators, integrating cardiovascular research within its broader clinical program.

Hormonal diseases

The department conducts endocrine studies focused on chronic hypoparathyroidism, testing a recombinant peptide to enhance calcium homeostasis and improve patient well‑being.

  • Chronic hypoparathyroidism treatment
  • Calcium and vitamin D regulation
  • Hormone replacement strategies
  • Bone health and metabolic balance

These investigations complement the hospital’s efforts in metabolic health and support a multidisciplinary approach to hormonal disorders.

Immune System Diseases

Researchers are evaluating targeted biologics such as rocatinlimab in combination with topical therapies for moderate‑to‑severe atopic dermatitis, seeking faster skin clearance and sustained disease control.

  • Atopic dermatitis biologic therapy
  • Combination with corticosteroids or calcineurin inhibitors
  • Eczema Area and Severity Index improvement
  • Immune pathway modulation

This work leverages the site’s expertise in immune modulation, aligning with its oncology immunotherapy programs.

Neoplasms

A core research focus is on advanced solid tumors, where innovative immunotherapies including nivolumab, relatlimab, and botensilimab are studied to extend progression‑free survival and improve response rates in melanoma, colorectal, and ovarian cancers.

  • Advanced melanoma (treated and refractory)
  • Metastatic colorectal cancer with dMMR
  • Advanced epithelial ovarian cancer
  • Unresectable melanoma treatment
  • Adjuvant therapy for resected melanoma

The oncology unit leads 13 active trials, reflecting a strong commitment to advancing cancer care.

Nutritional and Metabolic Diseases

Clinical studies target obesity and related metabolic conditions, evaluating a multi‑agonist peptide retatrutide for weight reduction and exploring its potential benefits for knee osteoarthritis.

  • Obesity and overweight management
  • Knee osteoarthritis symptom relief
  • Metabolic syndrome intervention
  • Weight‑loss efficacy assessment

By integrating metabolic research with oncology, the site offers patients access to cutting‑edge therapeutic options.

Site Overview

assignment
225
connected trials
corporate_fare
117
sponsors
science
360
IMPs

Activity Indicator

Last 6 months

24
Trials started
-14% vs previous period.
28
Trials started 6–12 months ago
225
Total trials linked
Highly Active
trending_downDeclining-14%
4
3
6
7
3
1
Mar
Apr
May
Jun
Jul
Aug

Trial Flow

How this site's trials are distributed across therapeutic areas and active substances (IMPs), and how they're positioned within their overall lifecycle status. Flow thickness represents the number of unique trials.

Therapeutic areaarrow_forwardIMParrow_forwardLifecycle status

Top 3 of 24 therapeutic areas and 15 of 360 IMPs, ranked by number of trials.

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Compounds & Molecules Timeline

The time span of clinical-trial activity for the main active substances (IMPs) studied at this site over the last 8 years. Each bar runs from the earliest trial start to the most recent end; a substance with a trial still open has no recorded end and is shown as ongoing.

Trial span Ongoing Showing last 8 years

Top 40 of 338 compounds, ranked by number of trials.

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Sponsor & Partnership

Top sponsors by active trials, and the ones that have come back for more than one study.

Active trials
102
Sponsors (total)
117
Active sponsors
71

Sponsor Network

Top 71 by active trials.

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Partnership History

Sponsors with repeated collaboration (≥ 2 trials).

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Sponsor Network Graph

How sponsors and therapeutic areas connect across this site's active trials: each link is at least one active trial shared between them, and bigger nodes mean more activity. Click a node to see its exact connections.

Country Benchmark

Compared to 567 other sites in Spain

description
Trial volume
225
Outperforms 95% of sites
public
Therapeutic diversity
24areas
Outperforms 95% of sites
groups
Sponsor diversity
117sponsors
Outperforms 95% of sites

Therapeutic Area Benchmark — Spain

Select a therapeutic area to compare against other sites in Spain.

Competitor Comparison

Similar sites in the same country running a comparable number of trials (within ±30%), scored on how closely their trial portfolios match this one. Higher percentages mean a more similar profile.

Country: Spain

Market Share

Country: Spain

Therapeutic Area Market Share

Select a therapeutic area to view its disease coverage breakdown.

Heat Maps & Advanced Analytics

How often specific conditions appear in trials across this site and comparable sites from the same country. Each row is a site, each column a condition, and each cell the number of trials on it — darker means more activity.

Other Trials in Hospital General Universitario De Valencia

lock Showing 1 of 225 trials — the rest is available on a paid plan.

Trial Sponsor Phase Status Start Date End Date
(22153) Randomized, Double-Masked, Active-Controlled, Phase 3 Study of the Efficacy and Safety of Aflibercept 8 mg in Macular Edema Secondary to Retinal Vein OcclusionBayer AGPhase IIINot RecruitingSep 2023May 2025

IMP list

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IMP Trials Status First start Last start
Pembrolizumab31Unknown2018-08-242026-06-16

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