Jorge R. K.
- Country
- Germany
- Department
- Klinik für Innere Medizin
Research Overview
- Phase III Randomized Trial of AZD0901 with Capecitabine ± Rilvegostomig in First‑Line Claudin‑18.2‑Positive HER2‑Negative Advanced Gastric, GEJ or Esophageal Adenocarcinoma
- Phase III Randomized Open-Label Study of Regorafenib and Nivolumab Versus Standard Chemotherapy in Refractory Advanced Gastro-Oesophageal Cancer
- Evaluation of Adjuvant Therapy with Capecitabine in Stage II Colon and Rectal Cancer Patients with ctDNA Positivity Post-Resection
Data & Insights
Has run more than one trial at 154 of 363 partner sites.
Specializations
Gastrointestinal Oncology
The investigator specializes in treating advanced gastric cancer and gastroesophageal junction adenocarcinoma, exploring innovative therapeutic approaches in both early-stage and metastatic settings.
- Perioperative treatment strategies
- Neoadjuvant therapy approaches
- Advanced therapeutic combinations
Particular focus on integrating immunotherapy with conventional treatment modalities for gastroesophageal cancers.
Colorectal Cancer Research
Expertise in treating metastatic colorectal cancer with special attention to microsatellite instability high (MSI-H) and mismatch repair deficient disease variants.
- Post-resection therapeutic strategies
- Biomarker-driven treatment approaches
- Circulating tumor DNA analysis
Advanced work in adjuvant therapy optimization and personalized treatment approaches for stage II and III disease.
Immunotherapy Applications
Leading research in immune checkpoint inhibition across gastrointestinal cancers, investigating novel combinations with targeted therapies and conventional chemotherapy.
- Checkpoint inhibitor combinations
- Novel immunotherapy agents
- Biomarker-guided immunotherapy
Focus on identifying optimal patient populations for immunotherapy-based treatment approaches.
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