Maria F. E.
- Country
- Portugal
- Department
- Gastroenterology
Research Overview
- Phase 3 Randomized Study of Telisotuzumab Vedotin vs. Docetaxel in c-Met Overexpressing EGFR Wildtype Non-Squamous NSCLC
- Efficacy and Safety of Atezolizumab Versus Best Supportive Care Post-Adjuvant Cisplatin-Based Chemotherapy in Resected Stage IB-IIIA Non-Small Cell Lung Cancer
- Evaluation of Durvalumab Plus Oleclumab and Durvalumab Plus Monalizumab in Stage III Unresectable Non-Small Cell Lung Cancer Post-Platinum-Based Chemoradiation
Data & Insights
Has run more than one trial at 56 of 299 partner sites.
Specializations
Medical Oncology and Solid Tumor Care
Clinical research activity includes a strong focus on breast cancer, non-small cell lung cancer, head and neck squamous cell carcinoma, gastric cancer, urothelial carcinoma, and multiple myeloma, with interest in both advanced disease and earlier treatment settings.
- HER2-positive breast cancer
- ER-positive, HER2-negative breast cancer
- Metastatic non-small cell lung cancer
- Head and neck squamous cell carcinoma
- Urothelial carcinoma
The therapeutic landscape also includes biomarker-driven oncology, immunotherapy, and strategies aimed at improving disease control in recurrent, metastatic, and treatment-resistant cancers.
Inflammatory and Autoimmune Diseases
Research involvement extends across ulcerative colitis, Crohn's disease, atopic dermatitis, rheumatoid arthritis, systemic lupus erythematosus, systemic sclerosis, and Sjögren’s disease, reflecting a broad commitment to immune-mediated disorders.
- Ulcerative colitis
- Crohn's disease
- Atopic dermatitis
- Systemic lupus erythematosus
- Systemic sclerosis
Additional interest includes hidradenitis suppurativa, psoriatic arthritis, immune thrombocytopenia, and other chronic inflammatory conditions requiring targeted long-term management.
Cardiovascular and Thromboembolic Disorders
The investigator is active in studies of heart failure, atrial fibrillation, atherosclerotic cardiovascular disease, stroke prevention, aortic stenosis, and transcatheter aortic valve implantation, with emphasis on cardiovascular risk reduction and event prevention.
- Heart failure
- Atrial fibrillation
- Stroke prevention
- Atherosclerotic cardiovascular disease
- Severe aortic stenosis
Her clinical trial portfolio also includes hyperlipidemia, hypertension, and antithrombotic strategies relevant to high-risk vascular disease.
Nephrology, Metabolic, and Endocrine Conditions
Research interests cover IgA nephropathy, focal segmental glomerulosclerosis, chronic kidney disease, Wilson disease, type 2 diabetes, obesity, and severe hypertriglyceridemia, supporting care across renal and metabolic disease pathways.
- IgA nephropathy
- Focal segmental glomerulosclerosis
- Chronic kidney disease
- Type 2 diabetes
- Obesity
There is also involvement in classic congenital adrenal hyperplasia, hypoparathyroidism, and lipid disorders linked to cardiometabolic risk.
Neurology, Pulmonology, and Other Specialty Areas
Clinical research activity further includes epilepsy, Parkinson’s disease, multiple sclerosis, migraine, idiopathic pulmonary fibrosis, pulmonary arterial hypertension, and cystic fibrosis, showing engagement with complex chronic disorders across multiple specialties.
- Epilepsy
- Parkinson’s disease
- Multiple sclerosis
- Idiopathic pulmonary fibrosis
- Pulmonary arterial hypertension
Additional areas include diabetic retinopathy, geographic atrophy, infectious diseases, and hematologic disorders such as hemophilia and myelofibrosis.
Related Investigators
Researchers in similar fields or departments
Want to know more about this investigator?
We can share extended profile information and contact details.
Is something out of date?
Tell us what needs correcting and we'll update this profile.