Delphine H. G.
- Country
- France
- Department
- Anesthésie-Réanimation - Hôpital Salengro
Research Overview
- Evaluation of Inhaled Dornase Alfa Versus Placebo in Reducing Moderate to Severe ARDS Incidence in Ventilated Severe Trauma Patients in ICU
- Intermediate versus standard dose enoxaparin to prevent venous thromboembolism in severe trauma patients: a multicenter double blind randomised controlled trial (HEPTRAUMA)
Data & Insights
Has run more than one trial at 7 of 15 partner sites.
Specializations
Critical Care and Perioperative Medicine
Clinical research in anesthesiology and intensive care medicine covers severe respiratory failure, septic shock, acute kidney injury, and postoperative support after major surgery.
- Septic shock and hemodynamic instability
- Mechanical ventilation and respiratory support
- Postoperative complications and pain management
- Acute organ dysfunction in the ICU
Therapeutic interest also extends to emergency stabilization, sedation strategies, and organ-protective care in critically ill adults and children.
Hematology and Blood Disorders
The investigator is involved in studies of hematologic malignancies and immune-mediated blood diseases, including acute leukemia, lymphoma, multiple myeloma, and thrombocytopenia.
- Acute lymphoblastic leukemia and acute myeloid leukemia
- Diffuse large B-cell lymphoma and mantle cell lymphoma
- Multiple myeloma and myelodysplastic syndromes
- Immune thrombocytopenia and hemolytic anemia
Research activity also includes allogeneic stem cell transplantation, graft-versus-host disease, and post-transplant infectious complications.
Neurology and Neuroinflammatory Disease
Clinical interest includes multiple sclerosis, epilepsy, stroke, Parkinson's disease, and immune-mediated neuropathies such as chronic inflammatory demyelinating polyneuropathy and anti-MAG neuropathy.
- Demyelinating disorders and inflammatory neuropathies
- Acute ischemic stroke and intracerebral hemorrhage
- Epileptic syndromes and refractory seizures
- Neurodegenerative conditions
Therapeutic work also spans cognitive disorders, headache syndromes, and neuromuscular diseases requiring targeted neurological care.
Autoimmune, Rheumatologic, and Inflammatory Diseases
The research profile includes systemic lupus erythematosus, rheumatoid arthritis, Sjögren's disease, systemic sclerosis, and other systemic autoimmune diseases.
- Lupus nephritis and cutaneous lupus
- Systemic sclerosis with interstitial lung disease
- Vasculitis and inflammatory myopathies
- Immune-mediated arthritis and connective tissue disease
Additional therapeutic focus is seen in inflammatory bowel disease, Crohn's disease, and ulcerative colitis, reflecting broad involvement in chronic immune-mediated disorders.
Oncology and Targeted Cancer Therapy
Investigational activity also covers solid tumors and advanced cancers, with emphasis on lung cancer, gastrointestinal malignancies, melanoma, and pancreatic cancer.
- Non-small cell lung cancer and small cell lung cancer
- Gastric, colorectal, and esophageal cancers
- Melanoma and cutaneous squamous cell carcinoma
- Hepatocellular carcinoma and biliary tract cancer
Research interests include immunotherapy, targeted therapy, and treatment approaches for refractory or metastatic disease across multiple tumor types.
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