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Centre Hospitalier Universitaire De Lille

Address
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Cardiovascular and Vascular Research

At Centre Hospitalier Universitaire De Lille, clinical trials in cardiovascular diseases focus on major conditions such as acute coronary syndrome, acute myocardial infarction, heart failure, and transcatheter aortic valve implantation-related care. These studies are designed to test new treatment strategies and improve patient outcomes after serious heart and vessel events.

  • Reducing recurrent cardiovascular events after heart attack
  • Improving recovery after ST-segment elevation myocardial infarction
  • Evaluating safer approaches for aortic stenosis procedures
  • Tracking treatment effects in heart failure due to left ventricular systolic dysfunction

Overall, this area combines prevention, recovery, and treatment optimization for people with high-risk cardiac disease.

Pulmonary and Thoracic Oncology

The site has a strong focus on respiratory tract diseases and neoplasms, especially non-small cell lung cancer, small cell lung cancer, pulmonary hypertension, and pulmonary arterial hypertension. Research here is aimed at testing new cancer therapies, improving survival, and finding better ways to control chronic lung conditions.

  • Testing new treatments for metastatic non-small cell lung cancer
  • Evaluating options for small cell lung cancer and pleural mesothelioma
  • Studying therapies for pulmonary arterial hypertension
  • Assessing care for chronic obstructive pulmonary disease

These trials reflect a broad effort to advance both thoracic oncology and lung disease management through more effective and targeted approaches.

Hematology and Bleeding Disorders

Clinical research in hemic and lymphatic diseases includes studies in hemophilia A and B and lymphatic malformations. The main goal is to improve disease control, monitor joint health, and evaluate new options for people living with inherited bleeding or lymphatic conditions.

  • Assessing joint outcomes in hemophilia patients on preventive treatment
  • Exploring therapy for PIK3CA mutation-associated lymphatic malformations
  • Supporting better long-term management of bleeding disorders

This research area is centered on practical improvements in symptom control, complication prevention, and quality of life.

Cell Signaling and Rare Disease Research

Work in cell physiological phenomena at the site includes studies of disease mechanisms linked to PIK3CA and c-Met or EGFR alterations. These trials aim to better understand how abnormal cell signaling drives disease and to evaluate more precise treatment options.

  • Testing targeted therapy for PIK3CA mutation-related disease
  • Evaluating treatment approaches for EGFR exon 20 insertion lung cancer
  • Studying c-Met overexpressing non-small cell lung cancer

By focusing on molecular features of disease, this research supports more personalized care for selected cancer and rare disease populations.

Site Overview

assignment
1015
connected trials
corporate_fare
287
sponsors
science
956
IMPs

Activity Indicator

Last 6 months

89
Trials started
+7% vs previous period.
83
Trials started 6–12 months ago
1015
Total trials linked
Highly Active
trending_upGrowing+7%
13
20
19
17
15
5
Mar
Apr
May
Jun
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Aug

Trial Flow

How this site's trials are distributed across therapeutic areas and active substances (IMPs), and how they're positioned within their overall lifecycle status. Flow thickness represents the number of unique trials.

Therapeutic areaarrow_forwardIMParrow_forwardLifecycle status

Top 5 of 37 therapeutic areas and 15 of 956 IMPs, ranked by number of trials.

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Compounds & Molecules Timeline

The time span of clinical-trial activity for the main active substances (IMPs) studied at this site over the last 8 years. Each bar runs from the earliest trial start to the most recent end; a substance with a trial still open has no recorded end and is shown as ongoing.

Trial span Ongoing Showing last 8 years

Top 40 of 897 compounds, ranked by number of trials.

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Sponsor & Partnership

Top sponsors by active trials, and the ones that have come back for more than one study.

Active trials
554
Sponsors (total)
287
Active sponsors
195

Sponsor Network

Top 195 by active trials.

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Partnership History

Sponsors with repeated collaboration (≥ 2 trials).

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Sponsor Network Graph

How sponsors and therapeutic areas connect across this site's active trials: each link is at least one active trial shared between them, and bigger nodes mean more activity. Click a node to see its exact connections.

Country Benchmark

Compared to 978 other sites in France

description
Trial volume
1 015
Outperforms 99% of sites
public
Therapeutic diversity
38areas
Outperforms 99% of sites
groups
Sponsor diversity
287sponsors
Outperforms 99% of sites

Therapeutic Area Benchmark — France

Select a therapeutic area to compare against other sites in France.

Competitor Comparison

Similar sites in the same country running a comparable number of trials (within ±30%), scored on how closely their trial portfolios match this one. Higher percentages mean a more similar profile.

Country: France

Market Share

Country: France

Therapeutic Area Market Share

Select a therapeutic area to view its disease coverage breakdown.

Heat Maps & Advanced Analytics

How often specific conditions appear in trials across this site and comparable sites from the same country. Each row is a site, each column a condition, and each cell the number of trials on it — darker means more activity.

Other Trials in Centre Hospitalier Universitaire De Lille

lock Showing 1 of 1 015 trials — the rest is available on a paid plan.

Trial Sponsor Phase Status Start Date End Date
(21492 ARASTEP) A randomized, double-blind, placebo-controlled Phase 3 study of darolutamide plus androgen deprivation therapy (ADT) compared with placebo plus ADT in patients with high-risk biochemical recurrence (BCR) of prostate cancerBayer AG, Bayer Consumer Care AGPhase IIINot RecruitingOct 2023

IMP list

lock Showing 1 of 956 compounds — the rest is available on a paid plan.

IMP Trials Status First start Last start
Pembrolizumab54Unknown2015-07-162026-02-06

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