Angelo Baldassare C.
- Country
- Italy
- Department
- #3655:U.O.C. Astanteria - Medicina e Chirurgia d'Accettazione e d'Urgenza
Research Overview
- Effect of Olpasiran on Major Cardiovascular Events in Patients with Atherosclerotic Cardiovascular Disease and Elevated Lipoprotein(a): A Randomized, Placebo-Controlled Study
- Effect of Muvalaplin on Major Adverse Cardiovascular Events in Adults With Elevated Lipoprotein(a) and Atherosclerotic Cardiovascular Disease: A Phase 3 Randomized Trial
- Evaluation of Obicetrapib on Major Adverse Cardiovascular Events in Atherosclerotic Cardiovascular Disease Patients on Maximal Lipid-Modifying Therapy
Data & Insights
Has run more than one trial at 424 of 904 partner sites.
Specializations
Cardiovascular and Metabolic Disease
Clinical research activity includes atherosclerotic cardiovascular disease, atrial fibrillation, hypertension, dyslipidemia, hypertriglyceridemia, familial hypercholesterolemia, and obesity, with interest in risk reduction and cardiometabolic complications.
- Atherosclerotic cardiovascular disease
- Hypertriglyceridemia
- Atrial fibrillation
- Obesity
Additional work extends to type 2 diabetes, post-bariatric hypoglycaemia, heart failure, and major adverse cardiovascular events.
Hepatology and Gastrointestinal Disorders
Research involvement covers primary biliary cholangitis, primary sclerosing cholangitis, metabolic dysfunction-associated steatotic liver disease, non-alcoholic steatohepatitis, portal hypertension, and hepatic encephalopathy.
- Primary biliary cholangitis
- Non-alcoholic steatohepatitis
- Portal hypertension
- Hepatic encephalopathy
Therapeutic interest also includes cholestatic pruritus, cirrhosis, alpha-1 antitrypsin deficiency-associated liver disease, and inflammatory bowel disease such as ulcerative colitis and Crohn's disease.
Oncology and Hematologic Malignancies
Clinical trial activity spans non-small cell lung cancer, hepatocellular carcinoma, head and neck squamous cell carcinoma, melanoma, breast cancer, and several sarcoma subtypes.
- Acute myeloid leukemia
- Multiple myeloma
- Hepatocellular carcinoma
- Gastrointestinal stromal tumor
Additional areas include follicular lymphoma, diffuse large B-cell lymphoma, myelodysplastic syndromes, and advanced or metastatic solid tumors.
Neurology, Autoimmune Disease, and Respiratory Medicine
Research interests include migraine, Alzheimer's disease, multiple sclerosis, amyotrophic lateral sclerosis, myasthenia gravis, and autoimmune encephalitis.
- Alzheimer's disease
- Myasthenia gravis
- Multiple sclerosis
- Migraine
Further involvement extends to asthma, chronic obstructive pulmonary disease, bronchiectasis, acute respiratory distress syndrome, and viral respiratory infections.
Autoimmune, Renal, and Rare Disease Therapeutics
Clinical activity also includes systemic sclerosis, Sjögren's disease, psoriatic arthritis, gout, chronic kidney disease, and focal segmental glomerulosclerosis.
- Sjögren's syndrome
- Systemic sclerosis
- Chronic kidney disease
- Gout
Additional therapeutic areas include thyroid eye disease, haemophilia A, monkeypox virus disease, and Clostridioides difficile infection.
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