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Azienda Ospedaliera Universitaria Policlinico Paolo Giaccone

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Ophthalmology and Eye Diseases

At Azienda Ospedaliera Universitaria Policlinico Paolo Giaccone, clinical research in Eye Diseases focuses on common and vision-threatening conditions, with studies aimed at improving treatment outcomes and post-surgical recovery.

  • Neovascular Age-Related Macular Degeneration
  • Thyroid Eye Disease
  • Postoperative inflammation after cataract surgery

This area includes trials testing new therapies and evaluating how to better control inflammation and preserve visual function.

Oncology and Hematologic Malignancies

A major part of the site’s research portfolio covers Neoplasms and blood cancers, with studies designed to assess new cancer treatments, compare them with standard care, and improve disease control.

  • Breast Cancer
  • Multiple Myeloma
  • Acute Myeloid Leukemia
  • Head and Neck Squamous Cell Carcinoma

These trials explore both targeted and immunotherapy-based approaches, aiming to extend survival and refine treatment strategies for difficult-to-treat cancers.

Cardiovascular and Metabolic Research

The site conducts extensive studies in Cardiovascular Diseases and Metabolic Disorders, reflecting a strong interest in prevention, risk reduction, and long-term disease management.

  • Atherosclerotic Cardiovascular Disease
  • Atrial Fibrillation
  • Hypertension
  • Type 2 Diabetes Mellitus
  • Obesity

Research here often evaluates new therapies for lowering cardiovascular risk, improving blood sugar control, and supporting healthier weight and lipid profiles.

Liver and Digestive System Disorders

A substantial share of trials at this hospital address Digestive System Diseases, especially chronic liver conditions and inflammatory bowel disease, with an emphasis on symptom relief and slowing progression.

  • Primary Biliary Cholangitis
  • Non-Alcoholic Steatohepatitis
  • Chronic Hepatitis B
  • Ulcerative Colitis
  • Crohn's disease

The research includes studies of new treatments for liver inflammation, fibrosis, cholestatic symptoms, and bowel inflammation.

Neurology, Immunology, and Autoimmune Disease

Clinical trials in Nervous System Diseases and Immune System Diseases investigate conditions that affect movement, memory, and immune regulation, with a focus on symptom control and disease slowing.

  • Alzheimer's Disease
  • Amyotrophic Lateral Sclerosis
  • Multiple Sclerosis
  • Generalized Myasthenia Gravis
  • Sjögren’s Syndrome

The studies aim to test new therapies, improve patient-reported outcomes, and better understand autoimmune and neurodegenerative disease activity.

Respiratory, Infectious, and Inflammatory Conditions

Research at the site also spans Respiratory Tract Diseases, Virus Diseases, and inflammatory disorders, supporting efforts to improve infection control and long-term symptom management.

  • Asthma
  • Bronchiectasis
  • Pneumonia
  • Respiratory Syncytial Virus Infections
  • HIV Infections

These trials are designed to evaluate treatment effectiveness, reduce exacerbations, and strengthen care for patients with chronic or recurrent respiratory and infectious diseases.

Rare Diseases, Genetic Disorders, and Other Specialized Studies

The portfolio at Policlinico Paolo Giaccone also includes specialized research in rare and complex conditions, combining Analytical, Diagnostic and Therapeutic Techniques with targeted disease-specific studies.

  • Primary Myelofibrosis
  • Familial Hypercholesterolemia
  • Congenital Adrenal Hyperplasia
  • Alpha-1 Antitrypsin Deficiency-Associated Liver Disease
  • Neuroendocrine tumors

This work supports earlier diagnosis, better risk assessment, and the development of more precise therapies for uncommon and hard-to-treat diseases.

Site Overview

assignment
185
connected trials
corporate_fare
94
sponsors
science
269
IMPs

Activity Indicator

Last 6 months

18
Trials started
-22% vs previous period.
23
Trials started 6–12 months ago
185
Total trials linked
Highly Active
trending_downDeclining-22%
3
3
8
1
3
Mar
Apr
May
Jun
Jul
Aug

Trial Flow

How this site's trials are distributed across therapeutic areas and active substances (IMPs), and how they're positioned within their overall lifecycle status. Flow thickness represents the number of unique trials.

Therapeutic areaarrow_forwardIMParrow_forwardLifecycle status

Top 4 of 24 therapeutic areas and 15 of 269 IMPs, ranked by number of trials.

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Compounds & Molecules Timeline

The time span of clinical-trial activity for the main active substances (IMPs) studied at this site over the last 8 years. Each bar runs from the earliest trial start to the most recent end; a substance with a trial still open has no recorded end and is shown as ongoing.

Trial span Ongoing Showing last 8 years

Top 40 of 252 compounds, ranked by number of trials.

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Sponsor & Partnership

Top sponsors by active trials, and the ones that have come back for more than one study.

Active trials
88
Sponsors (total)
94
Active sponsors
55

Sponsor Network

Top 55 by active trials.

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Partnership History

Sponsors with repeated collaboration (≥ 2 trials).

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Sponsor Network Graph

How sponsors and therapeutic areas connect across this site's active trials: each link is at least one active trial shared between them, and bigger nodes mean more activity. Click a node to see its exact connections.

Country Benchmark

Compared to 566 other sites in Italy

description
Trial volume
185
Outperforms 92% of sites
public
Therapeutic diversity
24areas
Outperforms 95% of sites
groups
Sponsor diversity
94sponsors
Outperforms 92% of sites

Therapeutic Area Benchmark — Italy

Select a therapeutic area to compare against other sites in Italy.

Competitor Comparison

Similar sites in the same country running a comparable number of trials (within ±30%), scored on how closely their trial portfolios match this one. Higher percentages mean a more similar profile.

Country: Italy

Market Share

Country: Italy

Therapeutic Area Market Share

Select a therapeutic area to view its disease coverage breakdown.

Heat Maps & Advanced Analytics

How often specific conditions appear in trials across this site and comparable sites from the same country. Each row is a site, each column a condition, and each cell the number of trials on it — darker means more activity.

Other Trials in Azienda Ospedaliera Universitaria Policlinico Paolo Giaccone

lock Showing 1 of 185 trials — the rest is available on a paid plan.

Trial Sponsor Phase Status Start Date End Date
(Peak) A Phase 3 Randomized, Open-label, Multicenter Clinical Study of CGT9486+Sunitinib vs Sunitinib in Subjects with Locally Advanced, Unresectable, or Metastatic Gastrointestinal Stromal TumorsCogent Biosciences Inc.Phase IIINot RecruitingMar 2023

IMP list

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IMP Trials Status First start Last start
Dexamethasone8Unknown2022-04-192025-04-30

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