A Phase 1 Study to Evaluate the Safety and Pharmacokinetics of MK-4605 in Healthy Participants
- Trial ID
- 2026-525627-24-00
- Protocol
- MK-4605-001
- Sponsor
- Merck Sharp & Dohme LLC
Trial statistics
Diseases & Conditions
Objectives
The primary objective of this study is to evaluate the safety and tolerability of MK-4605 in healthy participants. Determining the safety profile is a critical step in assessing the potential for clinical application in the management of dementia.
Participants
The sponsor did not provide information regarding the total number of participants. The study population consists of healthy volunteers within the age group represented by code 3. The cohort is composed of males. No specific data regarding lifestyle considerations, inclusion criteria, or exclusion criteria were provided.
Plans and Procedures
This is a Phase 1 clinical trial evaluating the effects of MK-4605 in healthy participants. The study follows a research methodology designed to assess the safety and pharmacological properties of the investigational product. The trial sequence begins with a screening visit to determine eligibility. Subsequent follow-up visits are scheduled to monitor clinical parameters and safety data. The protocol concludes with an end-of-study visit. The total duration of participant involvement is determined by the specific study schedule. Conditions leading to early termination from the study may include the occurrence of adverse events or failure to meet predefined safety criteria.
Treatment
Efficacy
The assessment of efficacy in this clinical trial regarding Dementia is not specified in the provided documentation. Therefore, no information concerning endpoints, measurement methodologies, or assessment schedules can be detailed.
Trial Status by Country
| Country | Status | Start of Recruitment | Planned Patients |
|---|---|---|---|
Belgium | Not Recruiting | 20 May 2026 | 16 |

