Clinical Research

Vseobecna Fakultni Nemocnice V Praze

Address
U Nemocnice 499/2, Nove Mesto

Sponsor Overview

assignment
2
sponsored trials
science
12
molecules
location_city
3
research centres
public
1
country
person_search
4
investigators

Specializations

Obstetrics and Maternal-Fetal Medicine

Clinical research in preterm premature rupture of membranes focuses on pregnancy management, infection-related complications, and strategies to support pregnancy prolongation while protecting maternal and neonatal health.

  • Premature rupture of membranes
  • Antibiotic and steroid-based treatment
  • Maternal and neonatal outcomes

Interest in individualized care for complicated pregnancy conditions is reflected in work addressing inflammatory markers and treatment selection in amniotic fluid.

Ophthalmology and Autoimmune Eye Disease

Research activity includes non-infectious uveitis, with attention to immune-mediated ocular inflammation and symptom control in chronic inflammatory eye disorders.

  • Autoimmune uveitis
  • Ocular inflammation
  • Inflammatory eye disease

The sponsor’s clinical interest extends to therapies aimed at modulating immune activity in uveitis and related vision-threatening conditions.

Microbiome-Based Therapy and Immunomodulation

One area of interest is the use of probiotic approaches in inflammatory disease, particularly where gut-derived microbial interventions may influence immune balance and disease activity.

  • Escherichia coli Nissle 1917
  • Probiotic treatment
  • Immune regulation

This research direction connects microbiome science with therapeutic exploration in autoimmune conditions.

Sponsored Trials

Trial Name Country Status
Evaluation of Escherichia coli Strain Nissle 1917 in the Management of Autoimmune Non-Infectious Uveitis: A 12-Month Follow-Up StudyCzechia CzechiaRecruiting
Evaluation of Tailored Antibiotic and Steroid Therapy Based on IL-6 in Amniotic Fluid for Prolonging Pregnancy in Preterm Premature Rupture of MembranesCzechia CzechiaRecruiting

Data & Insights

science
Molecule Portfolio
Compounds under investigation
0
Exclusive Molecules
out of 12 total (0% not shared with other sponsors)

This sponsor works with 12 molecules, of which 0 are not being studied by other sponsors.

hub
Site Partnerships
Collaboration with research centres
33%
Return partnership rate
1 of 3 sites collaborated multiple times

This sponsor has worked with 3 sites across their trial portfolio.

Therapeutic Focus

  • 1.
    Eye Diseases1 trial
    138 other sponsors
  • 2.
    Female Urogenital Diseases and Pregnancy Complications1 trial
    142 other sponsors
  • 3.
    Immune System Diseases1 trial
    322 other sponsors

Partnered Research Centres

3 centres
location_city
assignment363
Fakultni Nemocnice Brno
Address
Jihlavska 340/20, Bohunice, 625 00 Brno
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location_city
assignment7
The Institute For The Care Of Mother And Child
Address
157, Podolske Nabrezi 1110, Podoli, 147 00 Prague
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location_city
assignment379
Vseobecna Fakultni Nemocnice V Praze
Address
Ke Karlovu 455/2, Nove Mesto, 120 00 Prague
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