Ventus Therapeutics U.S. Inc.
- Address
- 100 Beaver Street Suite 201
Sponsor Overview
Specializations
Cutaneous lupus erythematosus and systemic lupus erythematosus
Ventus Therapeutics U.S. Inc. is active in clinical research for cutaneous lupus erythematosus, including cases with or without systemic lupus erythematosus, with a clear focus on immune-mediated skin disease and related autoimmune involvement.
- Autoimmune skin inflammation
- Interferon gene signature modulation
- Lupus-associated cutaneous disease
The sponsor’s lupus-focused studies place emphasis on disease activity in the skin and the underlying immune dysregulation associated with lupus-spectrum disorders.
Immunology and inflammatory disease
Its clinical portfolio includes research centered on immune pathway biology, particularly mechanisms linked to type I interferon activity and inflammatory signaling in autoimmune conditions.
- Immune-mediated disease
- Inflammatory signaling
- Skin immune biomarkers
These studies reflect a therapeutic interest in diseases where immune activation contributes to persistent tissue inflammation and clinical symptoms.
Neuroinflammatory and neurodegenerative diseases
Ventus Therapeutics U.S. Inc. also funds research in neuroinflammatory and neurodegenerative diseases, extending its therapeutic scope beyond autoimmune dermatology into nervous system disorders with inflammatory and degenerative components.
- Central nervous system inflammation
- Neurodegeneration
- Immune-neural interactions
This area of interest aligns with broader investigation of disease mechanisms that connect inflammation and progressive neurological injury.
Early clinical pharmacology and healthy volunteer studies
The sponsor maintains a program in healthy volunteers to explore pharmacokinetics, pharmacodynamics, tolerability, and food and interaction effects for orally administered candidates.
- Safety and tolerability
- Drug exposure and disposition
- Oral therapeutics
These studies support development across multiple therapeutic areas, including autoimmune and neurological indications.
Sponsored Trials
| Trial Name | Country | Status |
|---|---|---|
| Phase 1 Study of VENT-03: Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics in Healthy Volunteers for Lupus Erythematosus |  The Netherlands | Not Recruiting |
| Phase 2a Multicenter, Randomized, Double-Blind, Placebo-Controlled Study of VENT-03 in Adults with Active Cutaneous Lupus Erythematosus |  Bulgaria Czechia France Hungary Poland Spain | Recruiting |
| Phase I Study of VENT-02 in Neuroinflammatory and Neurodegenerative Diseases in Healthy Volunteers | The Netherlands | Not Recruiting |
Data & Insights
This sponsor works with 1 molecule, of which 1 is not being studied by other sponsors.
This sponsor has worked with 20 sites across their trial portfolio.
Therapeutic Focus
- 1.Immune System Diseases2 trials323 other sponsors
- 2.Nervous System Diseases1 trial449 other sponsors
Partnered Research Centres
20 centres- Address
- Ulitsa Persenk 19, Enter B Floor 1 App 13, 1407 Sofia
- Address
- Zernikedreef 8, 2333 CL Leiden
- Address
- Ul. Tarnopolska 77, 41-807 Zabrze
- Address
- Ul. Sokolowska 9/u2, 01-142 Warsaw
- Address
- Ulitsa Perushtitsa 1a, 4002 Plovdiv
- Address
- Ulitsa Stefan Stambolov 2, 6304 Haskovo
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