Clinical Research

UZ Brussel

Address
Laarbeeklaan 101

Sponsor Overview

assignment
23
sponsored trials
science
32
molecules
location_city
17
research centres
public
1
country
person_search
35
investigators

Specializations

Reproductive Medicine and Fertility Care

IVF, ICSI, and oocyte cryopreservation are central areas of interest, alongside studies in oocyte donation, ovarian stimulation, and fertility support for endometriosis and adenomyosis.

  • Oocyte retrieval pain management
  • Elective oocyte cryopreservation
  • Subfertility and female infertility prevention
  • Endometriosis-related reproductive outcomes

Research also includes treatment approaches for early pregnancy loss and interventions aimed at improving reproductive success in women undergoing assisted reproduction.

Oncology and Cancer Immunotherapy

The sponsor is active in melanoma, non-small cell lung cancer, solid tumors, and brain metastasis, with additional work in glioblastoma and astrocytoma.

  • Advanced melanoma
  • Lung and breast cancer
  • Brain metastases
  • High-grade glioma

Its cancer portfolio also covers radiation-induced lung injury and molecular imaging approaches linked to tumour and immune-cell characterization.

Perioperative Care and Pain Control

Clinical research includes perioperative analgesia, anxiety management, and anesthesia in both adult and pediatric settings, with attention to surgical comfort and procedural tolerance.

  • Postoperative pain after hernia surgery
  • Perioperative anxiety in children
  • Intubation in morbid obesity
  • Shoulder pain and disability in frozen shoulder

Work in this area also addresses adhesive capsulitis and frozen shoulder, including diagnostic assessment and symptom relief strategies.

Infectious Diseases and Antimicrobial Treatment

UZ Brussel supports studies in Staphylococcus aureus bacteremia and urinary tract infection with systemic involvement, reflecting interest in serious bacterial infections and treatment optimization.

  • Bloodstream infection due to Staphylococcus aureus
  • Systemic urinary tract infection
  • Antibiotic treatment strategies
  • Clinical cure in male UTI

These studies focus on infection management in hospitalized patients and the evaluation of antibacterial approaches in complicated disease.

Metabolic, Endocrine, and Other Chronic Conditions

The sponsor’s research also spans type 2 diabetes mellitus, obesity, heart failure, and cannabis dependence, with interest in symptom control and metabolic health.

  • Vitamin D and testosterone in type 2 diabetes
  • Obesity-related anesthesia considerations
  • Heart failure
  • Cannabis dependence

Additional activity includes care for inguinal hernia and other surgical or medical conditions requiring targeted clinical evaluation.

Sponsored Trials

Trial Name Country Status
Assessment of 68Ga-NOTA-Anti-HER2 VHH1 Uptake in Brain Metastases of HER2-Positive and HER2-Negative Cancer PatientsBelgium BelgiumNot Recruiting
Comparison of Random Start Ovarian Stimulation Versus Conventional Early Follicular Phase Stimulation in Elective Oocyte Cryopreservation Using Dydrogesterone, Follitropin Alfa, and Triptorelin AcetateBelgium BelgiumRecruiting
Comparison of Rocuronium Bromide Dosing Based on Ideal Versus Actual Body Weight for Intubation in Morbidly Obese Patients with Propofol and Sodium ChlorideBelgium BelgiumNot Yet Recruiting
Dose-Finding Study of Recombinant FSH Following Corifollitropin Alfa in Subfertility Patients Undergoing IVF/ICSI with GnRH Antagonist ProtocolBelgium BelgiumNot Recruiting
Evaluation of a New Pain Management Regime for Oocyte Pick-Up During Fertility TreatmentBelgium BelgiumNot Yet Recruiting
Evaluation of Analgesic Efficacy of Transversus Abdominis Plane Block Versus Local Infiltration with Ropivacaine Hydrochloride in Laparoscopic Inguinal Hernia RepairBelgium BelgiumRecruiting
Evaluation of Colecalciferol Supplementation on Free Testosterone Levels in Men with Type 2 Diabetes Mellitus: A Placebo-Controlled Randomized TrialBelgium BelgiumRecruiting
Evaluation of Handheld-Multimedia Versus Midazolam Premedication on Perioperative Anxiety in Pediatric Day-Care Patients: A Randomized Controlled TrialBelgium BelgiumRecruiting
Evaluation of Intra-Articular Corticosteroid Injection and Suprascapular Nerve Block in Patients with Adhesive Capsulitis Using Methylprednisolone Acetate and Ropivacaine HydrochlorideBelgium BelgiumRecruiting
Evaluation of Luteal Phase Ovarian Stimulation with Follitropin Delta and Dydrogesterone in Oocyte Donors: A Randomized Crossover Pilot StudyBelgium BelgiumRecruiting
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Data & Insights

science
Molecule Portfolio
Compounds under investigation
3
Exclusive Molecules
out of 32 total (9% not shared with other sponsors)

This sponsor works with 32 molecules, of which 3 are not being studied by other sponsors.

hub
Site Partnerships
Collaboration with research centres
29%
Return partnership rate
5 of 17 sites collaborated multiple times

This sponsor has worked with 17 sites across their trial portfolio.

Therapeutic Focus

  • 1.
    Anesthesia and Analgesia3 trials
    100 other sponsors
  • 2.
    Female Urogenital Diseases and Pregnancy Complications3 trials
    142 other sponsors
  • 3.
    Bacterial Infections and Mycoses2 trials
    180 other sponsors
  • 4.
    Neoplasms2 trials
    853 other sponsors
  • 5.
    Not possible to specify2 trials
    220 other sponsors
  • 6.
    Pathological Conditions, Signs and Symptoms2 trials
    91 other sponsors
  • 7.
    Reproductive and Urinary Physiological Phenomena2 trials
    33 other sponsors
  • 8.
    Cardiovascular Diseases1 trial
    359 other sponsors
  • 9.
    Diagnosis1 trial
    83 other sponsors
  • 10.
    Digestive System Diseases1 trial
    280 other sponsors
  • 11.
    Male Urogenital Diseases1 trial
    111 other sponsors
  • 12.
    Mental Disorders1 trial
    150 other sponsors
  • 13.
    Musculoskeletal Diseases1 trial
    238 other sponsors
  • 14.
    Musculoskeletal and Neural Physiological Phenomena1 trial
    28 other sponsors
  • 15.
    Nutritional and Metabolic Diseases1 trial
    211 other sponsors
  • 16.
    Skin and Connective Tissue Diseases1 trial
    247 other sponsors
  • 17.
    Surgical Procedures, Operative1 trial
    58 other sponsors

Partnered Research Centres

17 centres
location_city
assignment26
Algemeen Stedelijk Ziekenhuis Campus Aalst
Address
Merestraat 80, 9300 Aalst
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location_city
assignment1
Algemeen Ziekenhuis Diest
Address
Statiestraat 65, 3290 Diest
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location_city
assignment2
Algemeen Ziekenhuis Jan Palfijn Gent
Address
Watersportlaan 5, 9000 Ghent
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location_city
assignment6
AZ Rivierenland
Address
's Herenbaan 172, 2840 Rumst
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location_city
assignment191
Az St-Jan Brugge-Oostende A.V.
Address
Ruddershove 10, 8000 Bruges
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location_city
assignment134
Centre Hospitalier Regional De La Citadelle
Address
Boulevard Du Douzieme De Ligne 1, 4000 Liège
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