Clinical Research

Universitair Ziekenhuis Antwerpen

Address
Drie Eikenstraat 655

Sponsor Overview

assignment
20
sponsored trials
science
50
molecules
location_city
81
research centres
public
5
countries
person_search
142
investigators

Specializations

Hematologic Malignancies and Cellular Immunotherapy

Research activity in acute myeloid leukemia centers on relapse prevention, post-remission disease control, and immune-based approaches using dendritic cell vaccination and WT1-targeted therapies. The sponsor also supports work in advanced and refractory solid tumors with similar antigen-directed immunotherapy strategies.

  • Relapsed/refractory acute myeloid leukemia
  • WT1 mRNA-electroporated dendritic cell vaccination
  • Advanced or refractory solid tumors

These studies reflect a strong interest in therapeutic cancer immunology and cell-based treatment concepts in difficult-to-treat malignancies.

Thoracic and Gastrointestinal Oncology

The sponsor funds studies in malignant pleural mesothelioma, colon carcinoma, and selected advanced tumors of the pancreas, esophagus, liver, and ovaries. Research spans immunotherapy combinations, perioperative cancer care, and survival-focused treatment strategies in progressive disease.

  • Malignant pleural mesothelioma
  • Colon carcinoma
  • Advanced gastrointestinal and ovarian tumors

Additional work includes somatostatin analogue management in neuroendocrine tumours, broadening the oncology portfolio across thoracic and digestive cancers.

Neuro-Oncology and Pediatric Neurologic Disease

Clinical research includes glioblastoma, high-grade glioma, and diffuse intrinsic pontine glioma, with attention to adjuvant immune-based strategies in both adult and pediatric settings. The sponsor also supports studies in multiple sclerosis and progressive multiple sclerosis, including tolerogenic cell therapies aimed at immune modulation.

  • Glioblastoma and high-grade glioma
  • Diffuse intrinsic pontine glioma
  • Multiple sclerosis and progressive multiple sclerosis

This area combines neuro-oncology with neuroimmunology, including investigational approaches based on myelin-directed and tumor-directed cellular therapies.

Inflammatory, Infectious, and Critical Care Conditions

Research extends to acute myocarditis, chronic hepatitis B infection, and care optimization for critically ill patients. These studies address immune-mediated cardiac disease, viral persistence, and fluid management in intensive care.

  • Acute myocarditis
  • Chronic hepatitis B infection
  • Critical care fluid management

The sponsor also includes work on pediatric sedation and related procedural care, adding a service-oriented clinical research component.

Reproductive, Ophthalmic, and Endocrine-Related Care

Additional studies cover infertility in women with tubal patency assessment, pediatric cataract surgery support, and growth-related treatment in children with short predicted height. These areas reflect interest in reproductive medicine, pediatric ophthalmology, and endocrine growth disorders.

  • Infertility and tubal evaluation
  • Pediatric cataract
  • Short predicted height

These projects broaden the sponsor’s clinical research activity beyond oncology and neurology into specialized women’s health, pediatric eye care, and growth medicine.

Sponsored Trials

Trial Name Country Status
Continuing Somatostatin Analogues Upon progression in Neuroendocrine tumour pAtients (SAUNA trial)Belgium BelgiumThe Netherlands The NetherlandsRecruiting
Evaluation of Adjuvant WT1 LAMP mRNA DC Immunotherapy and Temozolomide in Post-Surgical Chemoradiation for Newly Diagnosed Glioblastoma Grade IVBelgium BelgiumNot Recruiting
Evaluation of Atezolizumab and WT1 LAMP mRNA DC Vaccine in Combination with Platinum/Pemetrexed for Epithelioid Malignant Pleural MesotheliomaBelgium BelgiumRecruiting
Evaluation of Ethnicity's Impact on Viral Outcomes Post-Cessation of Tenofovir Alafenamide and Entecavir in HBeAg-Negative Chronic Hepatitis B PatientsBelgium BelgiumNot Recruiting
Evaluation of Ethyl Esters of Iodised Fatty Acids from Poppyseed Oil in Tubal Flushing for Infertility in Women with Patent Tubes at HyFoSyBelgium BelgiumNot Recruiting
Evaluation of Metformin Hydrochloride as an Adjunctive Therapy in Non-Active Progressive Multiple Sclerosis: A Phase IIb Randomized, Triple-Blind, Placebo-Controlled TrialBelgium BelgiumNot Recruiting
Evaluation of Sodium Chloride and Glucose Monohydrate Infusion Strategies in Critically Ill Patients: Impact on Mortality and Organ SupportBelgium BelgiumRecruiting
Evaluation of Somatropin and Letrozole in Enhancing Adult Height in Boys with Short Predicted Stature: A 4-Year Randomized Controlled TrialBelgium BelgiumNot Yet Recruiting
Evaluation of the Efficacy and Safety of Intracameral Phenylephrine Hydrochloride, Tropicamide, and Lidocaine Hydrochloride in Pediatric Cataract SurgeryBelgium BelgiumNot Recruiting
Evaluation of Venetoclax and Mercaptopurine Combination Therapy in Patients with Relapsed/Refractory Acute Myeloid LeukemiaBelgium BelgiumNot Yet Recruiting
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Data & Insights

science
Molecule Portfolio
Compounds under investigation
4
Exclusive Molecules
out of 50 total (8% not shared with other sponsors)

This sponsor works with 50 molecules, of which 4 are not being studied by other sponsors.

hub
Site Partnerships
Collaboration with research centres
33%
Return partnership rate
27 of 81 sites collaborated multiple times

This sponsor has worked with 81 sites across their trial portfolio.

Therapeutic Focus

  • 1.
    Neoplasms10 trials
    853 other sponsors
  • 2.
    Immune system processes6 trials
    65 other sponsors
  • 3.
    Therapeutics6 trials
    87 other sponsors
  • 4.
    Nervous System Diseases3 trials
    449 other sponsors
  • 5.
    Digestive System Diseases2 trials
    280 other sponsors
  • 6.
    Immune System Diseases2 trials
    322 other sponsors
  • 7.
    Respiratory Tract Diseases2 trials
    277 other sponsors
  • 8.
    Anesthesia and Analgesia1 trial
    100 other sponsors
  • 9.
    Cardiovascular Diseases1 trial
    359 other sponsors
  • 10.
    Eye Diseases1 trial
    138 other sponsors
  • 11.
    Female Urogenital Diseases and Pregnancy Complications1 trial
    142 other sponsors
  • 12.
    Hemic and Lymphatic Diseases1 trial
    249 other sponsors
  • 13.
    Hormonal diseases1 trial
    89 other sponsors
  • 14.
    Not possible to specify1 trial
    220 other sponsors
  • 15.
    Reproductive and Urinary Physiological Phenomena1 trial
    33 other sponsors
  • 16.
    Virus Diseases1 trial
    182 other sponsors

Partnered Research Centres

81 centres
location_city
assignment3
A Z Monica
Address
Florent Pauwelslei 1, 2100 Antwerp
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location_city
assignment52
Alessandro Manzoni Hospital
Address
Via Dell' Eremo 9, 23900 Lecco
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location_city
assignment26
Algemeen Stedelijk Ziekenhuis Campus Aalst
Address
Merestraat 80, 9300 Aalst
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location_city
assignment3
Algemeen Ziekenhuis Alma
Address
Ringlaan 15, 9900 Eeklo
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location_city
assignment25
Algemeen Ziekenhuis Damiaan Oostende
Address
Gouwelozestraat 100, 8400 Ostend
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location_city
assignment283
Algemeen Ziekenhuis Delta
Address
Deltalaan 1, 8800 Roeselare
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