Universitaetsspital Basel

Address: Petersgraben 4

Sponsor Overview

assignment

Specializations

Aortic valve disease and transcatheter aortic valve replacement

Clinical research includes aortic stenosis and peri-procedural management in patients undergoing TAVR, with interest in cardiovascular optimisation around valve intervention.

Aortic stenosis
Transcatheter aortic valve replacement
Beta blocker therapy

The sponsor is also involved in studies examining medication use in the setting of structural heart disease and valve replacement care.

Electrolyte disorders and water balance

Research activity covers hyponatremia and central diabetes insipidus, reflecting a focus on disorders of sodium regulation and fluid homeostasis.

Hyponatremia
Central diabetes insipidus
Plasma sodium concentration

Trials in this area address endocrine and metabolic conditions where maintaining stable electrolyte levels is clinically important.

Musculoskeletal medicine and knee osteoarthritis

The sponsor supports studies in patellofemoral osteoarthritis, with emphasis on cartilage-related treatment approaches for degenerative knee disease.

Patellofemoral osteoarthritis
Knee pain
Cartilage repair

This includes clinical interest in interventions targeting pain, function, and joint preservation in anterior knee osteoarthritis.

Neuroendocrinology and social-emotional processing

Research also extends to oxytocin-related effects on anxiety and recognition of facial and body expressions, indicating interest in neurobehavioral and endocrine mechanisms.

Oxytocin
Anxiety
Facial expression recognition

These studies connect hormonal signalling with emotional processing and behavioural outcomes in human participants.

Sponsored Trials

Trial Name	Country	Status
Effect of Oral Colchicine on Atrial Fibrillation Recurrence After Electrical Cardioversion: A Randomized, Placebo‑Controlled COLECTRO‑AF Trial	Germany	Not Yet Recruiting
Evaluation of Beta-Adrenergic Blockers on Outcomes in Patients Undergoing Transcatheter Aortic Valve Replacement for Aortic Stenosis	Austria Germany	Recruiting
Evaluation of Dabigatran Etexilate, Apixaban, Edoxaban, and Drug Combination for Secondary Prevention in Acute Ischemic Stroke Patients Without Atrial Fibrillation	Greece Spain	Not Yet Recruiting
Evaluation of Empagliflozin on Plasma Sodium Levels in Euvolemic and Hypervolemic Hyponatremia: A Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial	Germany The Netherlands	Recruiting
Evaluation of Intranasal Oxytocin in Central Diabetes Insipidus: A Double-Blind, Randomized, Placebo-Controlled Trial	Germany The Netherlands	Recruiting
Evaluation of N-TEC Implantation for Patellofemoral Osteoarthritis: A Randomized, Controlled, Multicenter Phase II Clinical Trial	Croatia Germany	Recruiting
Phase II Randomized Controlled Trial of Nasal Chondrocyte-Based Tissue Engineered Cartilage Implantation for Patellofemoral Osteoarthritis Treatment	Austria Croatia Germany Italy Poland Sweden The Netherlands	Recruiting