Umecrine Cognition AB
- Address
- Nanna Svartz Vag 6a
Sponsor Overview
Specializations
Primary Biliary Cholangitis
Umecrine Cognition AB focuses on primary biliary cholangitis, with clinical research centered on the symptoms that affect daily functioning in people living with this autoimmune liver disease.
- Hepatology
- Autoimmune cholestatic disease
- Liver-related symptom burden
The sponsor’s clinical activity is directed toward patients with non-cirrhotic disease and those with Child-Pugh class A cirrhosis, reflecting an interest in liver disease populations with preserved hepatic function.
Fatigue and Cognitive Symptoms
Its research places strong emphasis on fatigue and cognitive dysfunction associated with PBC, addressing two of the most burdensome non-structural manifestations of the disease.
- Chronic fatigue
- Cognitive impairment
- Neurocognitive symptom management
These areas point to a therapeutic interest in the neurological and quality-of-life consequences of cholestatic liver disorders.
Sleep and Neurosteroid-Related CNS Effects
The sponsor’s work also aligns with central nervous system-focused symptom research, particularly conditions linked to cognitive performance, alertness, and daytime functioning in liver disease.
- Neurosteroid modulation
- Central nervous system symptoms
- Functional cognitive outcomes
This therapeutic domain connects liver disease care with symptom-focused neurological research.
Clinical Pharmacology and Symptom-Targeted Treatment
Umecrine Cognition AB’s funded trial activity includes interest in clinical pharmacology, safety, and tolerability in relation to treatment of fatigue and cognitive symptoms in PBC.
- Symptom-targeted therapy
- Safety and tolerability assessment
- Pharmacokinetics
Its research activity spans multiple collaborating sites across Europe and other active countries, supporting clinical development in a rare liver disease setting.
Sponsored Trials
| Trial Name | Country | Status |
|---|---|---|
| Evaluation of Pharmacokinetics, Safety, and Efficacy of Golexanolone in Primary Biliary Cholangitis Patients with Fatigue and Cognitive Dysfunction |  Germany Greece Hungary Italy Spain | Not Recruiting |
Data & Insights
This sponsor works with 1 molecule, of which 1 is not being studied by other sponsors.
This sponsor has worked with 24 sites across their trial portfolio.
Therapeutic Focus
- 1.Digestive System and Oral Physiological Phenomena1 trial16 other sponsors
Partnered Research Centres
24 centres- Address
- Piazza Dell'ospedale Maggiore 3, 20162 Milan
- Address
- Via Nicolo' Giustiniani 2, 35128 Padua
- Address
- Via Del Vespro 129, 90127 Palermo
- Address
- Via Pozzuolo 330, 33100 Udine
- Address
- Semmelweis Utca 1, 5700 Gyula
- Address
- Kaszasdulo Utca 5, 1033 Budapest
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