Trevi Therapeutics Inc.

Address
195 Church Street

Sponsor Overview

assignment
1
sponsored trial
science
1
molecule
location_city
23
research centres
public
5
countries
person_search
26
investigators

Specializations

Idiopathic Pulmonary Fibrosis and Chronic Cough

Trevi Therapeutics Inc. focuses its clinical research activity on idiopathic pulmonary fibrosis with a particular interest in the burden of chronic cough associated with the disease. The sponsor’s trial activity is centered on respiratory symptoms that affect daily functioning and disease experience in pulmonary fibrosis.

  • Respiratory symptom management
  • Cough frequency assessment
  • Fibrotic lung disease

Its research in this area reflects a therapeutic emphasis on symptom relief in interstitial lung disease, especially where persistent cough is a major clinical concern.

Objective Cough Measurement and Digital Monitoring

The sponsor’s clinical work includes the use of objective digital cough monitoring to evaluate respiratory outcomes in IPF. This places emphasis on quantifying cough burden through direct measurement of 24-hour cough frequency.

  • Digital respiratory endpoints
  • Continuous cough monitoring
  • Symptom quantification

This area highlights interest in precise assessment tools for cough-related outcomes in pulmonary research.

Nalbuphine Extended-Release in Respiratory Symptom Care

Trevi Therapeutics is investigating nalbuphine extended-release for the treatment of cough in idiopathic pulmonary fibrosis, indicating a therapeutic focus on agents aimed at reducing respiratory symptom burden. The research is directed toward antitussive therapy in a chronic fibrotic lung condition.

  • Antitussive treatment
  • Extended-release oral therapy
  • Respiratory pharmacotherapy

This work sits within the broader field of symptom-directed pulmonary treatment, with attention to persistent cough in fibrotic lung disease.

Multinational Respiratory Clinical Research

The sponsor’s trial activity spans multiple countries and collaborating research sites, supporting clinical investigation in respiratory medicine across an international setting. The active research footprint is concentrated on a single pulmonary indication with cross-site participation.

  • International site network
  • Multicountry clinical research
  • Pulmonary trial operations

Its clinical interests remain centered on cough in idiopathic pulmonary fibrosis within a coordinated respiratory research program.

Sponsored Trials

Trial Name Country Status
Evaluation of Nalbuphine Hydrochloride Extended-Release Tablets for Cough Management in Idiopathic Pulmonary Fibrosis: A Randomized, Double-Blind, Placebo-Controlled StudyGermany GermanyItaly ItalyPoland PolandSpain SpainThe Netherlands The NetherlandsNot Recruiting

Data & Insights

science
Molecule Portfolio
Compounds under investigation
0
Exclusive Molecules
out of 1 total (0% not shared with other sponsors)

This sponsor works with 1 molecule, of which 0 are not being studied by other sponsors.

hub
Site Partnerships
Collaboration with research centres
0%
Return partnership rate
0 of 23 sites collaborated multiple times

This sponsor has worked with 23 sites across their trial portfolio.

Therapeutic Focus

  • 1.
    Respiratory Tract Diseases1 trial
    277 other sponsors

Partnered Research Centres

23 centres
location_city
assignment392
Azienda Ospedaliera di Padova
Address
Via Nicolo' Giustiniani 2, 35128 Padua
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location_city
assignment112
Azienda Ospedaliero Universitaria Ospedali Riuniti
Address
Viale Luigi Pinto 1, 71122 Foggia
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location_city
assignment300
Azienda Ospedaliero-Universitaria Policlinico G. Rodolico-San Marco Di Catania
Address
Via Santa Sofia 78, 95123 Catania
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location_city
assignment364
Bellvitge University Hospital
Address
Carrer De La Feixa Llarga S/N, 08907 L'hospitalet De Llobregat
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location_city
assignment518
Center For Pediatric And Adolescent Medicine Of The Johannes Gutenberg University Mainz
Address
Langenbeckstrasse 1, Oberstadt, 55131 Mainz
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location_city
assignment711
Erasmus Universitair Medisch Centrum Rotterdam (Erasmus MC)
Address
Dr. Molewaterplein 40, 3015 GD Rotterdam
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