Takeda Development Center Americas Inc.
- Address
- 500 Kendall Street
Sponsor Overview
Specializations
Inflammatory Bowel Disease and Gastrointestinal Inflammation
Takeda Development Center Americas Inc. funds research in ulcerative colitis, Crohn’s disease, chronic pouchitis, and complex perianal fistulas, with additional interest in pediatric and adult disease activity, mucosal healing, and remission outcomes. Its portfolio also includes studies in gastroesophageal reflux disease and erosive esophagitis, extending into pediatric gastrointestinal care.
- Ulcerative colitis
- Crohn’s disease
- Chronic pouchitis
- Perianal fistulizing disease
- GERD and erosive esophagitis
The sponsor’s gastrointestinal research spans both adult and pediatric populations, including refractory and moderate-to-severe inflammatory disease.
Immunology, Autoimmune Disease, and Dermatology
Takeda supports trials in plaque psoriasis, psoriatic arthritis, non-segmental vitiligo, and hidradenitis suppurativa, reflecting a strong focus on immune-mediated skin and joint disorders. Its immunology portfolio also includes primary immune thrombocytopenia, immune-mediated thrombotic thrombocytopenic purpura, and primary immunodeficiency diseases.
- Plaque psoriasis
- Psoriatic arthritis
- Vitiligo
- Hidradenitis suppurativa
- Immune thrombocytopenia and thrombotic thrombocytopenic purpura
Research in this area also covers secondary immunodeficiency and infection prophylaxis in immunocompromised patients.
Hematologic Malignancies and Myeloid Disorders
The sponsor funds studies in acute myeloid leukemia, Philadelphia chromosome-positive acute lymphoblastic leukemia, chronic myeloid leukemia, Hodgkin lymphoma, myelodysplastic syndromes, and myelofibrosis. Its hematology portfolio includes both malignant and bone marrow failure conditions, with attention to anemia and disease control in difficult-to-treat blood cancers.
- Acute myeloid leukemia
- Philadelphia chromosome-positive ALL
- Hodgkin lymphoma
- Myelodysplastic syndromes
- Myelofibrosis
Takeda’s oncology and hematology research also includes advanced solid tumours and metastatic cancer settings.
Neurology and Sleep Disorders
Takeda’s neuroscience research includes developmental and epileptic encephalopathies such as Dravet syndrome and Lennox-Gastaut syndrome, along with narcolepsy with cataplexy, narcolepsy without cataplexy, and multiple system atrophy. Additional work addresses attention-deficit/hyperactivity disorder and neurocognitive impairment in rare neurologic conditions.
- Dravet syndrome and Lennox-Gastaut syndrome
- Narcolepsy
- Multiple system atrophy
- ADHD
- Epileptic encephalopathies
The portfolio also includes pediatric neurologic research and long-term safety studies in rare central nervous system disorders.
Rare Diseases, Liver Disease, and Transplant-Related Infections
Takeda funds research in alpha-1 antitrypsin deficiency-associated liver disease, primary immunodeficiency diseases, Hunter syndrome, and cytomegalovirus infection in hematopoietic stem cell transplant and solid organ transplant recipients. Its rare disease work also includes severe von Willebrand disease, congenital or acquired bleeding disorders, and hepatic impairment.
- Alpha-1 antitrypsin deficiency-associated liver disease
- Primary immunodeficiency diseases
- Hunter syndrome
- Cytomegalovirus infection in transplant recipients
- Von Willebrand disease
These studies include both metabolic and inherited conditions, as well as infectious complications in highly vulnerable patient groups.
Sponsored Trials
Data & Insights
This sponsor works with 61 molecules, of which 13 are not being studied by other sponsors.
This sponsor has worked with 691 sites across their trial portfolio.
Therapeutic Focus
- 1.Digestive System Diseases15 trials280 other sponsors
- 2.Nervous System Diseases12 trials449 other sponsors
- 3.Hemic and Lymphatic Diseases11 trials249 other sponsors
- 4.Neoplasms7 trials853 other sponsors
- 5.Skin and Connective Tissue Diseases7 trials247 other sponsors
- 6.Immune System Diseases6 trials322 other sponsors
- 7.Musculoskeletal Diseases3 trials238 other sponsors
- 8.Nutritional and Metabolic Diseases3 trials211 other sponsors
- 9.Not possible to specify2 trials220 other sponsors
- 10.Behavioral Disciplines and Activities1 trial20 other sponsors
- 11.Congenital, Hereditary, and Neonatal Diseases and Abnormalities1 trial165 other sponsors
- 12.Virus Diseases1 trial182 other sponsors
Partnered Research Centres
691 centres- Address
- Ul. Rudolfa Weigla 5, 53-114 Wroclaw
- Address
- Ringstraße 60, 5280 Braunau am Inn
- Address
- Via Consolare Valeria N 1, 98124 Messina
- Address
- Moelleparkvej 4, 9000 Aalborg
- Address
- Palle Juul-Jensens Boulevard 99, 8200 Aarhus
- Address
- Calle Del Marques De La Valdavia 103 Bajo Local, 28100 Alcobendas
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