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Spero Therapeutics Inc.

Address
675 Massachusetts Avenue

Sponsor Overview

assignment
1
sponsored trial
science
4
molecules
location_city
66
research centres
public
9
countries
person_search
63
investigators

Specializations

Urinary Tract Infection and Pyelonephritis

Spero Therapeutics Inc. focuses on complicated urinary tract infection (cUTI) and acute pyelonephritis (AP) in hospitalized adults, with interest in serious bacterial infections affecting the urinary tract and kidneys.

  • Complicated urinary tract infection
  • Acute pyelonephritis
  • Hospitalized adult patients

The sponsor's clinical activity in this area centers on treatment options for infections that require inpatient care and careful assessment of clinical cure and microbiological eradication.

Antibacterial Therapy

The trial portfolio reflects an interest in oral antibacterial therapy for infections traditionally managed with intravenous antibiotics, highlighting a focus on gram-negative bacterial disease in the hospital setting.

  • Oral antibiotic treatment
  • Intravenous comparator therapy
  • Serious bacterial infections

This therapeutic area aligns with efforts to expand treatment choices for patients with infections that have limited oral options.

Inpatient Infectious Disease Care

Research activity is directed toward adult inpatient management of infection, with emphasis on conditions requiring structured clinical follow-up and outcome evaluation after treatment.

  • Adult inpatient care
  • Clinical outcome assessment
  • Microbiological response

The sponsor's current clinical focus remains concentrated on infection-related care pathways within acute hospital medicine.

Multinational Clinical Development

The sponsor supports research across multiple countries and collaborating sites, indicating an active interest in broad clinical evaluation of infectious disease therapies across diverse patient populations.

  • International trial participation
  • Collaborating research sites
  • Cross-border patient enrollment

This geographic reach is associated with the study of infection treatments in varied hospital environments.

Sponsored Trials

Trial Name Country Status
Phase 3 Randomized Study of Tebipenem Pivoxil Hydrobromide vs. Imipenem-Cilastatin in Complicated Urinary Tract Infection and Acute PyelonephritisBulgaria BulgariaCroatia CroatiaEstonia EstoniaGreece GreeceHungary HungaryLatvia LatviaPoland PolandRomania RomaniaSlovakia SlovakiaNot Recruiting

Data & Insights

science
Molecule Portfolio
Compounds under investigation
1
Exclusive Molecules
out of 4 total (25% not shared with other sponsors)

This sponsor works with 4 molecules, of which 1 is not being studied by other sponsors.

hub
Site Partnerships
Collaboration with research centres
0%
Return partnership rate
0 of 66 sites collaborated multiple times

This sponsor has worked with 66 sites across their trial portfolio.

Therapeutic Focus

  • 1.
    Bacterial Infections and Mycoses1 trial
    180 other sponsors

Partnered Research Centres

66 centres
location_city
assignment41
Clinical Hospital Dubrava
Address
Avenija Gojka Suska 6, Zagreb, 10000 Zagreb
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location_city
assignment24
Complex Oncological Center - Shumen EOOD
Address
Ulitsa Vasil Aprilov 63, 9705 Shumen
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location_city
assignment43
CRU Hungary Kft.
Address
Petofi Ut 26a, 3860 Encs
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location_city
assignment46
Daugavpils regionala slimnica SIA
Address
Viestura Iela 5, 5401 Daugavpils
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location_city
assignment204
Diagnostic-consultative center “Aleksandrovska” EOOD
Address
Triaditsa, Ulitsa Sveti Georgi Sofiyski 1, 1431 Sofia
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location_city
assignment139
Evangelismos S.A.
Address
Ipsiladou 45-47, 106 76 Athens
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