Clinical Research

Rheinische Friedrich-Wilhelms-Universitaet Bonn

Address
Venusberg-Campus 1, Venusberg

Sponsor Overview

assignment
12
sponsored trials
science
20
molecules
location_city
75
research centres
public
3
countries
person_search
126
investigators

Specializations

Neuroinflammation and acute cerebrovascular injury

Clinical research includes aneurysmal subarachnoid hemorrhage with a focus on inflammatory mechanisms and neurological recovery, alongside studies in glioblastoma that address tumour progression in the central nervous system.

  • Subarachnoid hemorrhage
  • Inflammation in acute brain injury
  • Glioblastoma

These areas reflect sustained interest in neurological disease states where immune modulation and tumour-directed therapy are central clinical concerns.

Oncology and surgical cancer care

The sponsor funds trials in non-small cell lung cancer, ovarian cancer, and malignant extracranial germ cell tumours, with additional attention to perioperative tumour detection and treatment-related outcomes.

  • Non-small cell lung cancer
  • Ovarian cancer
  • Malignant germ cell tumours
  • Intraoperative imaging

Research activity also spans glucocorticoid-sparing strategies and multimodal cancer treatment pathways in advanced solid tumours.

Autoimmune and inflammatory disorders

Several studies address chronic immune-mediated disease, including giant cell arteritis, lichen planus, and radiation-induced oral mucositis, with a strong emphasis on symptom control and disease activity.

  • Giant cell arteritis
  • Lichen planus
  • Oral mucositis
  • Immune system modulation

Related work also includes investigations into innate immune priming and inflammatory responses in healthy subjects.

Metabolic and reproductive health

Research activity covers overweight and obesity-related polycystic ovary syndrome, with attention to menstrual dysfunction and broader endocrine-metabolic disturbance.

  • Polycystic ovary syndrome
  • Ovarian dysfunction
  • Obesity-related endocrine disorders

These trials connect metabolic regulation with reproductive outcomes in women’s health.

Perioperative and pediatric care

The sponsor also supports studies in delayed gastric emptying after pancreatoduodenectomy and pediatric emergence delirium following ENT surgery, reflecting interest in postoperative recovery and anaesthesia-related complications.

  • Pancreatoduodenectomy outcomes
  • Delayed gastric emptying
  • Pediatric emergence delirium
  • Perioperative symptom management

Additional work addresses procedure-related complications and recovery patterns in both adult and paediatric settings.

Sponsored Trials

Trial Name Country Status
A Randomized, Double-Blind, Placebo-Controlled, Parallel Group Study to Evaluate the Efficacy of Methotrexate as Remission Maintenance Therapy after Remission-Induction Therapy with Tocilizumab and Glucocorticoids in Subjects with Giant Cell ArteritisGermany GermanyNot Recruiting
Efficacy of Deucravacitinib in Patients with Lichen Planus: A Multicenter, Phase II, Proof-of-Concept StudyGermany GermanyNot Recruiting
Evaluation of 5-Aminolevulinic Acid Hydrochloride for Intraoperative Imaging in Ovarian Cancer Detection: A Single-Center Feasibility StudyGermany GermanyRecruiting
Evaluation of Dexamethasone Sodium Phosphate in Acute Aneurysmal Subarachnoid Hemorrhage: A Randomized, Placebo-Controlled StudyGermany GermanyNot Recruiting
Evaluation of Dexpanthenol Mouth Rinse for the Prevention of Radiation-Induced Oral Mucositis in Patients Undergoing RadiotherapyGermany GermanyRecruiting
Evaluation of Tirzepatide for Ovarian Dysfunction in Overweight or Obese Patients with Polycystic Ovary Syndrome: A Randomized Controlled TrialGermany GermanyRecruiting
Evaluation of Transdermal Nicotine on Delayed Gastric Emptying Post-Pancreatoduodenectomy: A Randomized, Double-Blind, Placebo-Controlled Multicenter TrialGermany GermanyRecruiting
Investigation of Nucleoside Reverse Transcriptase Inhibitors on Innate Immune System Modulation in Healthy SubjectsGermany GermanyNot Recruiting
Phase I/II Evaluation of Meclofenamate Sodium and Temozolomide in Progressive MGMT-Methylated GlioblastomaGermany GermanyRecruiting
Phase II Randomized Trial of Induction Immunochemotherapy with Durvalumab, Cisplatin, Paclitaxel, and Vinorelbine in Resectable Stage IIIA/B NSCLCGermany GermanyRecruiting
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Data & Insights

science
Molecule Portfolio
Compounds under investigation
1
Exclusive Molecules
out of 20 total (5% not shared with other sponsors)

This sponsor works with 20 molecules, of which 1 is not being studied by other sponsors.

hub
Site Partnerships
Collaboration with research centres
29%
Return partnership rate
22 of 75 sites collaborated multiple times

This sponsor has worked with 75 sites across their trial portfolio.

Therapeutic Focus

  • 1.
    Neoplasms4 trials
    853 other sponsors
  • 2.
    Female Urogenital Diseases and Pregnancy Complications2 trials
    142 other sponsors
  • 3.
    Pathological Conditions, Signs and Symptoms2 trials
    91 other sponsors
  • 4.
    Digestive System Diseases1 trial
    280 other sponsors
  • 5.
    Hormonal diseases1 trial
    89 other sponsors
  • 6.
    Immune System Diseases1 trial
    322 other sponsors
  • 7.
    Immune System Phenomena1 trial
    15 other sponsors
  • 8.
    Immune system processes1 trial
    65 other sponsors
  • 9.
    Microbiological Phenomena1 trial
    9 other sponsors
  • 10.
    Nervous System Diseases1 trial
    449 other sponsors
  • 11.
    Not possible to specify1 trial
    220 other sponsors
  • 12.
    Nutritional and Metabolic Diseases1 trial
    211 other sponsors
  • 13.
    Skin and Connective Tissue Diseases1 trial
    247 other sponsors
  • 14.
    Surgical Procedures, Operative1 trial
    58 other sponsors
  • 15.
    Virus Diseases1 trial
    182 other sponsors

Partnered Research Centres

75 centres
location_city
assignment31
Asklepios Klinik Sankt Augustin GmbH
Address
Arnold-Janssen-Strasse 29, 53757 Sankt Augustin
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location_city
assignment14
Berufsgenossenschaftliches Universitaetsklinikum Bergmannsheil gGmbH
Address
Buerkle De La Camp-Platz 1, Wiemelhausen, 44789 Bochum
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location_city
assignment1
Bezirkskrankenhaus Giuenzburg
Address
Lindenallee 2, 89312 Guenzburg
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location_city
assignment518
Center For Pediatric And Adolescent Medicine Of The Johannes Gutenberg University Mainz
Address
Langenbeckstrasse 1, Oberstadt, 55131 Mainz
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location_city
assignment1047
Charite Universitaetsmedizin Berlin KöR
Address
Hindenburgdamm 30, Lichterfelde, 12203 Berlin
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location_city
assignment3
Childrens Hospital Of Koblenz
Address
Koblenzer Strasse 115-155, 56073 Koblenz
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