Resolution Therapeutics Limited
- Address
- 245 Hammersmith Road
Sponsor Overview
Specializations
Hepatic Fibrosis and Liver Cirrhosis
Resolution Therapeutics Limited focuses on clinical research in advanced liver disease, with particular attention to cirrhosis and the complications associated with decompensated liver cirrhosis. Its active trial portfolio reflects interest in disease states marked by progressive liver injury and impaired hepatic function.
- Liver Cirrhosis
- Decompensated Liver Disease
- Hepatic Repair
The sponsor’s research activity is centred on therapeutic approaches for patients with advanced hepatic disease, including cell-based strategies aimed at addressing serious liver impairment.
Cell Therapy and Macrophage Therapy
The company is engaged in research involving autologous macrophage therapy, with an emphasis on immune-cell-based treatment concepts for liver cirrhosis. This places cell therapy at the core of its clinical development work.
- Autologous Macrophage Therapy
- Immune Cell Therapy
- Regenerative Medicine
Its therapeutic interest includes the use of patient-derived cellular approaches to support treatment options for complex hepatic disorders.
Safety and Tolerability in Advanced Disease
Resolution Therapeutics Limited’s clinical research also places importance on the safety and tolerability of investigational therapies in people with severe liver conditions. The sponsor’s trial activity is directed toward understanding how novel treatments are received in a population with significant unmet medical need.
- Therapy Safety
- Tolerability Assessment
- Advanced Liver Disease
This area of interest is closely tied to treatment development for patients with limited options in decompensated cirrhosis.
Hepatology and Translational Medicine
The sponsor’s research landscape is rooted in hepatology, with clinical interest in translating novel biological therapies into care for cirrhosis. Its trial activity connects specialist liver medicine with emerging therapeutic platforms.
- Hepatology
- Translational Medicine
- Biological Therapy Development
Current clinical work is concentrated in the United Kingdom and involves collaboration across multiple research sites supporting liver-focused clinical investigation.
Sponsored Trials
| Trial Name | Country | Status |
|---|---|---|
| Evaluation of Safety, Tolerability, and Efficacy of RTX001 Autologous Macrophages and Filgrastim in Patients with Decompensated Liver Cirrhosis |  Spain | Not Recruiting |
Data & Insights
This sponsor works with 2 molecules, of which 1 is not being studied by other sponsors.
This sponsor has worked with 5 sites across their trial portfolio.
Therapeutic Focus
- 1.Digestive System Diseases1 trial280 other sponsors
Partnered Research Centres
5 centres- Address
- Paseo De La Castellana 261, 28046 Madrid
- Address
- Calle Del Doctor Esquerdo 46, 28007 Madrid
- Address
- Avenida Fernando Abril Martorell 106, 46026 Valencia
- Address
- Passeig De La Vall D'Hebron 119-129, 08035 Barcelona
- Address
- Avenida De Manuel Siurot S/n, 41013 Seville
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