PHRI Population Health Research Institute International
- Address
- 237 Barton Street East
Sponsor Overview
Specializations
Cardiovascular and Arrhythmia Research
Clinical activity is centered on atrial fibrillation in patients at elevated thromboembolic risk, with attention to treatment decisions in those with prior intracranial hemorrhage.
- Atrial fibrillation
- Stroke prevention
- Systemic embolism
The research focus includes balancing anticoagulant therapy against non-antithrombotic approaches in a high-risk cardiac population.
Neurology and Bleeding Risk
Another key area is the management of patients with a history of intracranial hemorrhage, where recurrent bleeding risk is clinically relevant to long-term treatment planning.
- Intracranial hemorrhage
- Hemorrhagic stroke
- Recurrent bleeding risk
This includes interest in outcomes that reflect both ischemic and hemorrhagic cerebrovascular events.
Antithrombotic and Anticoagulation Strategies
The sponsor’s trial portfolio examines edoxaban in relation to nonanticoagulant medical therapy, including antiplatelet monotherapy and no antithrombotic treatment.
- Edoxaban
- Antiplatelet therapy
- Nonanticoagulant medical therapy
These studies address therapeutic choices for patients in whom prevention of embolic events must be considered alongside prior bleeding history.
Multinational Clinical Research
Research operations extend across 10 countries and 65 collaborating sites, supporting enrollment in a geographically broad cardiovascular study network based in Hamilton, Canada.
- International site collaboration
- Recruitment in progress
- Population health research
The active program is organized through the ENRICH-AF Research Project Office.
Sponsored Trials
| Trial Name | Country | Status |
|---|---|---|
| Colchicine for Reducing Dependency and MACE in Acute Intracerebral Hemorrhage Survivors with Atherosclerotic Risk: Randomized Placebo-Controlled Trial |  Belgium Spain | Not Yet Recruiting |
| Evaluation of Edoxaban Versus Nonanticoagulant Therapy in High-Risk Atrial Fibrillation Patients with Prior Intracranial Hemorrhage |  Austria Belgium Czechia Germany Greece Portugal Spain | Not Recruiting |
Data & Insights
This sponsor works with 2 molecules, of which 0 are not being studied by other sponsors.
This sponsor has worked with 41 sites across their trial portfolio.
Therapeutic Focus
- 1.Cardiovascular Diseases2 trials359 other sponsors
Partnered Research Centres
41 centres- Address
- Gouwelozestraat 100, route 10, 8400 Ostend
- Address
- Carrer De La Feixa Llarga S/N, 08907 L'hospitalet De Llobregat
- Address
- BVD Patience Et Beaujonc, 2, Liège
- Address
- Rua da Junqueira 126, Lisbon
- Address
- Rua Jose Ant Nio Serrana, Lisbon
- Address
- Largo Professor Abel Salazar, 4050-011 Porto
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