Pharvaris Netherlands B.V.
- Address
- J.H. Oortweg 21
Sponsor Overview
Specializations
Hereditary Angioedema Prophylaxis
Pharvaris Netherlands B.V. focuses on preventive treatment strategies for hereditary angioedema, with research centred on reducing the frequency of swelling attacks in adults and adolescents living with C1 inhibitor deficiency.
- Long-term prophylactic therapy
- Attack prevention in HAE
- Oral treatment for recurrent angioedema
Its clinical portfolio includes work in both HAE due to C1-inhibitor deficiency and broader hereditary angioedema populations.
On-Demand Angioedema Treatment
The sponsor also investigates therapies intended for immediate use during acute angioedema attacks, including treatment of symptomatic episodes in hereditary angioedema and laryngeal attacks.
- Rapid symptom relief during attacks
- Acute attack management
- Self-administered oral therapy
Research in this area spans both adults and adolescents, with attention to episodic disease control.
Acquired Angioedema Research
Pharvaris Clinical extends its work to acquired angioedema due to C1 inhibitor deficiency, examining treatment options for both prevention and on-demand control of swelling episodes.
- AAE-C1INH prophylaxis
- On-demand relief for acquired angioedema
- Safety and tolerability in recurrent attacks
This area reflects interest in complement-mediated angioedema beyond inherited disease forms.
Oral Deucrictibant Development
The sponsor’s clinical programme is built around deucrictibant and PHA-022121, with research covering both extended-release formulations and soft capsule presentations for angioedema management.
- Extended-release oral formulations
- Prophylactic and on-demand use
- Pharmacokinetics and formulation performance
Related studies include evaluation in healthy volunteers to support oral delivery and treatment consistency.
Sponsored Trials
Data & Insights
This sponsor works with 3 molecules, of which 2 are not being studied by other sponsors.
This sponsor has worked with 53 sites across their trial portfolio.
Therapeutic Focus
- 1.Immune System Diseases6 trials322 other sponsors
- 2.Congenital, Hereditary, and Neonatal Diseases and Abnormalities5 trials165 other sponsors
- 3.Immune system processes3 trials65 other sponsors
- 4.Skin and Connective Tissue Diseases2 trials247 other sponsors
Partnered Research Centres
53 centres- Address
- De Boelelaan 1117, 1081 HV Amsterdam
- Address
- 26 Avenue Du Docteur Arnold Netter, 75012 Paris
- Address
- Via Giovanni Battista Grassi 74, 20157 Milan
- Address
- Via Nicolo' Giustiniani 2, 35128 Padua
- Address
- Via Ferdinando Magellano 1, 10128 Turin
- Address
- Via Trabucco 180, 90146 Palermo
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