Paion Pharma GmbH
- Address
- Heussstrasse 25, Brand
Sponsor Overview
Specializations
Paediatric Critical Care
Research activity is centred on children and adolescents with life-threatening hypotension requiring specialised intensive care support, with attention to haemodynamic instability in acute clinical settings.
- Paediatric intensive care
- 0–17 years
- Critical blood pressure support
The sponsor’s clinical interest in this area reflects a focus on severe circulatory compromise in young patients managed across multiple international research sites.
Distributive Shock
The trial portfolio includes distributive shock with refractory hypotension, covering acute vascular failure and persistent blood pressure instability despite standard treatment measures.
- Refractory hypotension
- Shock-related haemodynamics
- Vasopressor-dependent care
Clinical interest is directed toward severe circulatory collapse where conventional support remains insufficient to restore adequate arterial pressure.
Vasopressor Therapy
Research activity focuses on vasopressor support in the intensive care environment, including the management of patients receiving standard-of-care agents for persistent hypotension.
- Standard-of-care vasopressors
- Blood pressure stabilisation
- Circulatory support
This therapeutic area aligns with the sponsor’s interest in treatments that address acute haemodynamic rescue in critically ill paediatric patients.
Angiotensin II
The funded trial landscape includes investigation of angiotensin II as a treatment option for severe hypotension, with emphasis on its role in restoring vascular tone and supporting arterial pressure.
- Renin-angiotensin system
- Vascular tone regulation
- Haemodynamic rescue
Interest in this agent is tied to acute care settings where rapid correction of profound hypotension is clinically relevant.
Sponsored Trials
| Trial Name | Country | Status |
|---|---|---|
| Angiotensin II for Refractory Hypotension in Paediatric Patients With Distributive Shock: A Phase III Randomised Placebo-Controlled Trial |  France Germany Italy Spain | Not Yet Recruiting |
Data & Insights
This sponsor works with 2 molecules, of which 0 are not being studied by other sponsors.
This sponsor has worked with 22 sites across their trial portfolio.
Therapeutic Focus
- 1.Cardiovascular Diseases1 trial359 other sponsors
Partnered Research Centres
22 centres- Address
- 26 Avenue Du Docteur Arnold Netter, 75012 Paris
- Address
- Via Nicolo' Giustiniani 2, 35128 Padua
- Address
- Viale Gaetano Pieraccini 24, 50139 Florence
- Address
- 78 Rue Du General Leclerc, 94275 Le Kremlin-Bicetre
- Address
- 165 Chemin Du Grand Revoyet, 69310 Pierre Benite
- Address
- 2 Boulevard Tonnelle, 37044 Tours
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