Ospedale San Raffaele S.r.l.

The sponsor supports studies in multiple sclerosis, including relapsing-remitting and progressive forms, as well as research in migraine and neurodegenerative mechanisms. Additional work addresses Wolfram syndrome type 1, reflecting interest in complex neurological and neurogenetic conditions.

• Relapsing-remitting multiple sclerosis
• Progressive multiple sclerosis
• Migraine
• Wolfram syndrome type 1
• Neurodegenerative phenomena

Its neurological portfolio also touches on immune-mediated pathways and nervous system injury linked to chronic disease.

Clinical research in cardiology and critical care includes conditions such as cardiogenic shock, cardiac arrest, acute respiratory distress syndrome, low-cardiac output syndrome, dilated cardiomyopathy, and myocarditis. The sponsor also studies advanced support settings and postoperative cardiac complications.

• Cardiogenic shock and cardiac arrest
• Acute respiratory distress syndrome
• Low-cardiac output syndrome
• Dilated cardiomyopathy and myocarditis
• Perioperative cardiac support

Work in this area extends to thrombotic and bleeding risk, hemodynamic instability, and cardiopulmonary rescue care.

The sponsor’s research covers immune-mediated and systemic diseases including IgG4-related disease, new-onset autoimmune type 1 diabetes, and virus-negative myocarditis. It also includes studies in HIV infection and early treated HIV-1, alongside metabolic and endocrine conditions such as Wolfram syndrome type 1.

• IgG4-related disease
• Autoimmune type 1 diabetes
• Virus-negative myocarditis
• HIV infection and HIV-1
• Metabolic and endocrine syndromes

These studies reflect interest in immune regulation, chronic infection, and autoimmune tissue injury.

Ospedale San Raffaele S.r.l. also conducts research in rare genetic diseases and musculoskeletal disorders, including Duchenne muscular dystrophy, Von-Hippel Lindau disease, and arthroscopic anterior cruciate ligament reconstruction. Additional activity includes chronic pelvic pain syndrome and other complex pain-related conditions.

• Duchenne muscular dystrophy
• Von-Hippel Lindau disease
• Anterior cruciate ligament reconstruction
• Chronic pelvic pain syndrome
• Genetic and rare disease research

Its portfolio includes neuromuscular biology, inherited disease mechanisms, and surgical pain management.