Clinical Research

Ospedale Pediatrico Bambino Gesu'

Address
Piazza Sant'onofrio 4

Sponsor Overview

assignment
3
sponsored trials
science
5
molecules
location_city
2
research centres
public
1
country
person_search
3
investigators

Specializations

Paediatric nephrology

Research activity includes idiopathic steroid-sensitive nephrotic syndrome, with attention to complicated and relapsing disease in children.

  • Nephrotic syndrome
  • Relapse prevention
  • B-cell guided treatment

The clinical focus is on immune-mediated kidney disease and treatment strategies for paediatric patients with persistent or recurrent proteinuria.

Paediatric haematology

The sponsor is involved in studies of relapsed/refractory B-cell acute lymphoblastic leukemia in children and young adults.

  • Acute lymphoblastic leukemia
  • B-cell precursor disease
  • Refractory blood cancers

Its research interest extends to aggressive haematologic malignancies requiring advanced cellular therapies.

Paediatric immunotherapy

Trials include CD19-directed CAR T-cell approaches for B-cell acute lymphoblastic leukemia and related refractory disease settings.

  • CAR T-cell therapy
  • CD19 targeting
  • Cell-based oncology treatment

This area reflects a therapeutic interest in immune-engineered treatments for children and young adults with difficult-to-treat leukemia.

T-cell malignancies

Additional work addresses relapsed/refractory CD7+ T-cell acute lymphoblastic leukemia and lymphoblastic lymphoma.

  • T-cell acute lymphoblastic leukemia
  • Lymphoblastic lymphoma
  • CD7-targeted therapy

The sponsor’s clinical interest includes targeted cellular treatment options for aggressive T-lineage haematologic cancers.

Sponsored Trials

Trial Name Country Status
Phase I Trial of CD19-CAR_LENTI_ALLO, Fludarabine Phosphate, and Cyclophosphamide in Pediatric and Young Adult Relapsed/Refractory B-cell Acute Lymphoblastic LeukemiaItaly ItalyRecruiting
Phase I/II Evaluation of CD7-CART01, Cyclophosphamide, and Fludarabine Phosphate in Pediatric and Young Adult Relapsed/Refractory CD7+ T-ALL/Lymphoblastic LymphomaItaly ItalyRecruiting
Rituximab-Based Memory B Cell Level-Guided Therapy in Pediatric Complicated Steroid-Sensitive Nephrotic Syndrome: A Randomized Controlled TrialItaly ItalyNot Yet Recruiting

Data & Insights

science
Molecule Portfolio
Compounds under investigation
2
Exclusive Molecules
out of 5 total (40% not shared with other sponsors)

This sponsor works with 5 molecules, of which 2 are not being studied by other sponsors.

hub
Site Partnerships
Collaboration with research centres
50%
Return partnership rate
1 of 2 sites collaborated multiple times

This sponsor has worked with 2 sites across their trial portfolio.

Therapeutic Focus

  • 1.
    Hemic and Lymphatic Diseases2 trials
    249 other sponsors
  • 2.
    Female Urogenital Diseases and Pregnancy Complications1 trial
    142 other sponsors
  • 3.
    Male Urogenital Diseases1 trial
    111 other sponsors

Partnered Research Centres

2 centres
location_city
assignment176
IRCCS Istituto Giannina Gaslini
Address
Via Gerolamo Gaslini 5, 16147 Genoa
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location_city
assignment298
Ospedale Pediatrico Bambino Gesu'
Address
Piazza Sant'onofrio 4, 00165 Rome
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