Narodowy Instytut Kardiologii Stefana Kardynala Wyszynskiego Panstwowy Instytut Badawczy

Address
Alpejska 42

Sponsor Overview

assignment
9
sponsored trials
science
23
molecules
location_city
31
research centres
public
1
country
person_search
50
investigators

Specializations

Structural Heart Interventions and Periprocedural Anticoagulation

Research activity includes anticoagulation management around transseptal structural procedures, with attention to Transcatheter Edge-to-Edge Repair and Left Atrial Appendage Closure. The focus is on balancing thromboembolic protection and bleeding risk in patients undergoing invasive cardiac intervention.

  • Transseptal cardiac procedures
  • Anticoagulant therapy
  • Stroke prevention
  • Bleeding risk management

Additional interest extends to antiplatelet strategies after left atrial appendage closure in patients with complex cardiovascular comorbidity.

Coronary Artery Disease, Atherosclerosis, and Prediabetes

Clinical research covers coronary disease linked with metabolic risk, including coronary atherosclerosis and prediabetes. The therapeutic landscape centers on cardiovascular risk reduction and plaque-related disease progression.

  • Coronary artery disease
  • Coronary atherosclerosis
  • Metabolic cardiology
  • Anti-atherosclerotic treatment

Interest also includes oral glucose-lowering therapies with cardiovascular relevance, especially in relation to coronary plaque burden assessed over time.

Hypertrophic Cardiomyopathy and Atrial Fibrillation

A major area of focus is hypertrophic cardiomyopathy, particularly when complicated by atrial fibrillation and reduced functional capacity. The research portfolio addresses rhythm control, arrhythmia prevention, and exercise limitation in this inherited cardiac condition.

  • Atrial fibrillation prevention
  • Rhythm control strategies
  • Exercise capacity
  • Inherited cardiomyopathy

There is also interest in therapies aimed at maintaining sinus rhythm and limiting arrhythmic complications in patients with structural heart disease.

Fontan Circulation and Congenital Heart Disease

Research includes adults with functionally single ventricle physiology after Fontan operation, where the emphasis is on circulatory support and physical performance. This area reflects ongoing work in complex congenital heart disease.

  • Fontan circulation
  • Single ventricle physiology
  • Exercise intolerance
  • Pulmonary vascular resistance

Therapeutic interest also includes hemodynamic optimization in patients living with long-term consequences of congenital cardiac surgery.

Hypertension, Antiplatelet Therapy, and Arrhythmogenic Cardiomyopathy

The sponsor also studies difficult-to-treat hypertension, antiplatelet management in high-risk cardiovascular patients, and disease-modifying approaches in arrhythmogenic cardiomyopathy. These topics reflect a broad interest in vascular control, thrombosis prevention, and myocardial remodeling.

  • Resistant hypertension
  • Dual and single antiplatelet therapy
  • Arrhythmogenic cardiomyopathy
  • Cardiac remodeling

Related work includes treatment pathways for patients with renal impairment who require long-term cardiovascular antithrombotic care.

Sponsored Trials

Trial Name Country Status
Comparative Efficacy and Safety of Acetylsalicylic Acid and Clopidogrel in Atrial Fibrillation Patients Post-Left Atrial Appendage ClosurePoland PolandNot Yet Recruiting
Comparative Efficacy and Safety of Dual vs. Single Antiplatelet Therapy Post-Left Atrial Appendage Closure in End-Stage Renal Disease PatientsPoland PolandNot Yet Recruiting
Comparative Study of Antiatherosclerotic Efficacy of Semaglutide, Dapagliflozin, and Metformin in Coronary Artery Disease with PrediabetesPoland PolandRecruiting
Comparative Study of Early Ablation Versus Amiodarone, Bisoprolol, and Sotalol in Preventing Atrial Fibrillation Recurrence in Hypertrophic Cardiomyopathy PatientsPoland PolandNot Recruiting
Evaluation of Empagliflozin on Exercise Capacity in Patients with Hypertrophic Cardiomyopathy: A Randomized, Placebo-Controlled TrialPoland PolandNot Recruiting
Evaluation of Eplerenone, Spironolactone, and Torasemide in the Management of Resistant Hypertension in Patients with Uncontrolled Blood PressurePoland PolandRecruiting
Evaluation of Heparin Sodium Versus Placebo for Optimizing Periprocedural Anticoagulation in Patients Undergoing Transseptal InterventionsPoland PolandNot Yet Recruiting
Evaluation of Sacubitril/Valsartan in Preventing Disease Progression in Patients with Arrhythmogenic Right Ventricular Cardiomyopathy: A Multicenter Randomized TrialPoland PolandRecruiting
Evaluation of Sildenafil on Exercise Capacity in Adults with Functionally Single Ventricle Post-Fontan Procedure: A Randomized Controlled TrialPoland PolandRecruiting

Data & Insights

science
Molecule Portfolio
Compounds under investigation
0
Exclusive Molecules
out of 23 total (0% not shared with other sponsors)

This sponsor works with 23 molecules, of which 0 are not being studied by other sponsors.

hub
Site Partnerships
Collaboration with research centres
29%
Return partnership rate
9 of 31 sites collaborated multiple times

This sponsor has worked with 31 sites across their trial portfolio.

Therapeutic Focus

  • 1.
    Cardiovascular Diseases9 trials
    359 other sponsors
  • 2.
    Circulatory and Respiratory Physiological Phenomena1 trial
    16 other sponsors
  • 3.
    Congenital, Hereditary, and Neonatal Diseases and Abnormalities1 trial
    165 other sponsors
  • 4.
    Physiological processes1 trial
    28 other sponsors

Partnered Research Centres

31 centres
location_city
assignment32
1 Wojskowy Szpital Kliniczny Z Poliklinika samodzielny publiczny zakład opieki zdrowotnej W Lublinie
Address
Ul. Aleje Raclawickie 23, 20-049 Lublin
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location_city
assignment1
Centrum Diagnostyki i Leczenia Nadciśnienia Tętniczego i Cukrzycy dr n. med. Piotr Kubalski
Address
ul. Poniatowskiego 15, 86-300 Grudziądz
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location_city
assignment1
Centrum Medyczno- Diagnostyczne Sp. z o.o.
Address
ul. Terespolska 12, 08-110 Siedlce
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location_city
assignment47
Gornoslaskie Centrum Mwdyczne
Address
Ul. Ziolowa 45/47, 40-635 Katowice
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location_city
assignment84
Krakowski Szpital Specjalistyczny im Jana Pawła II
Address
Ul. Pradnicka 80, 31-202 Krakow
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location_city
assignment1
Leszek Kamiński Specjalistyczny Gabinet Lekarski
Address
ul Kościuszki 2A, 37-200 Przeworsk
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