Merz Pharmaceuticals GmbH
- Address
- Eckenheimer Landstrasse 100, Nordend-West
Sponsor Overview
Specializations
Neuromuscular Disorders
Clinical research in lower limb spasticity associated with stroke and traumatic brain injury, with attention to motor impairment affecting gait and ankle function.
- Adult spasticity
- Ankle plantar flexor dysfunction
- Post-stroke motor impairment
- Traumatic brain injury-related spasticity
Interest is centered on therapeutic options for reducing muscle overactivity in the lower limbs.
Pediatric Neurology
Trials also focus on pediatric lower limb spasticity linked to cerebral palsy, addressing movement limitation in children and adolescents.
- Cerebral palsy
- Childhood spasticity
- Adolescent motor disorders
- Lower extremity tone abnormalities
The therapeutic emphasis includes functional improvement in developing patients with chronic neuromotor conditions.
Botulinum Toxin Therapy
Research activity includes the clinical evaluation of botulinum toxin formulations for managing focal spasticity in both adult and pediatric populations.
- NT 201
- Focal muscle hypertonia
- Injection-based spasticity treatment
- Neuromuscular modulation
This work reflects a strong focus on targeted interventions for localized movement disorders.
Functional Mobility and Rehabilitation
The sponsor’s clinical interests extend to outcomes relevant to mobility, walking ability, and lower limb function in patients affected by spasticity.
- Gait impairment
- Lower extremity function
- Muscle tone control
- Movement limitation
These areas are central to the therapeutic management of neuromotor disability.
Sponsored Trials
| Trial Name | Country | Status |
|---|---|---|
| Efficacy and Safety of Clostridium Botulinum Neurotoxin Type A in Pediatric Lower Limb Spasticity Due to Cerebral Palsy: A Randomized, Double-Blind, Placebo-Controlled Study |  Latvia Poland | Not Recruiting |
| Efficacy and Safety of NT 201 in Treating Lower Limb Spasticity Post-Stroke or Traumatic Brain Injury in Adults: A Randomized, Double-Blind, Placebo-Controlled Study |  Belgium Czechia France Germany Hungary Italy Poland Slovakia Spain | Not Recruiting |
Data & Insights
This sponsor works with 1 molecule, of which 0 are not being studied by other sponsors.
This sponsor has worked with 35 sites across their trial portfolio.
Therapeutic Focus
- 1.Nervous System Diseases2 trials449 other sponsors
Partnered Research Centres
35 centres- Address
- Viale Luigi Pinto 1, 71122 Foggia
- Address
- Corso Giuseppe Mazzini 18, 28100 Novara
- Address
- Zemgales Priekspilseta, Vienibas Gatve 45, 1004 Riga
- Address
- Rue Michel Polonovski, 59037 Lille
- Address
- Place Louise Godin 15, 5000 Namur
- Address
- Wawrzyńca Surowieckiego 8, 02-783 Warsaw
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