Kiniksa Pharmaceuticals GmbH
- Address
- Grafenaustrasse 5
Sponsor Overview
Specializations
Sjögren’s Disease
Clinical research in Sjögren’s disease focuses on immune-mediated glandular and systemic involvement, with attention to disease activity, symptom burden, and inflammatory control.
- Systemic autoimmune disease activity
- Exocrine gland dysfunction
- Immune modulation
These studies reflect interest in therapeutic approaches for both local dryness symptoms and broader autoimmune manifestations.
Recurrent Pericarditis
Research in well-controlled recurrent pericarditis centers on maintaining remission, reducing inflammatory flares, and supporting stable long-term disease control.
- Pericardial inflammation
- Relapse prevention
- Long-term symptom control
The therapeutic focus includes strategies for patients transitioning from prior pericarditis treatments to monotherapy maintenance.
Immunology and Inflammation
The sponsor’s trial portfolio is rooted in immune-mediated disease research, with emphasis on pathways involved in chronic inflammation and tissue-specific immune dysfunction.
- Autoimmune pathophysiology
- Inflammatory disease control
- Targeted immunotherapy
This area links the company’s work across rheumatologic and cardiovascular inflammatory conditions.
Long-term Disease Management
Clinical activity also includes research into sustained treatment effects, with attention to maintaining efficacy over time in chronic conditions requiring ongoing management.
- Maintenance therapy
- Durable efficacy
- Chronic care optimization
These studies address both continuity of care and persistent control of inflammatory disease activity.
Sponsored Trials
| Trial Name | Country | Status |
|---|---|---|
| A Phase 2 Study to Evaluate the Efficacy and Safety of Transitioning to KPL-387 Monotherapy in Participants with Well-Controlled Recurrent Pericarditis |  France Germany Greece Italy Poland Spain | Recruiting |
| Efficacy and Safety Evaluation of KPL-404 in a Phase 2 Randomized, Double-blind, Placebo-controlled Study for Sjögren’s Disease |  Czechia France Germany Hungary Poland Spain | Not Recruiting |
Data & Insights
This sponsor works with 1 molecule, of which 1 is not being studied by other sponsors.
This sponsor has worked with 51 sites across their trial portfolio.
Therapeutic Focus
- 1.Cardiovascular Diseases1 trial359 other sponsors
- 2.Eye Diseases1 trial138 other sponsors
- 3.Immune System Diseases1 trial322 other sponsors
- 4.Musculoskeletal Diseases1 trial238 other sponsors
- 5.Skin and Connective Tissue Diseases1 trial247 other sponsors
- 6.Stomatognathic Diseases1 trial16 other sponsors
- 7.Therapeutics1 trial87 other sponsors
Partnered Research Centres
51 centres- Address
- Ul. Topolowa 28, 82-300 Elblag
- Address
- Vassileos Pavlou Avenue 1, 166 73 Voula
- Address
- Via Giovanni Battista Grassi 74, 20157 Milan
- Address
- Piazza Dell'ospedale Maggiore 3, 20162 Milan
- Address
- Via Cherasco 15, 10126 Turin
- Address
- Largo Giovanni Alessandro Brambilla 3, 50134 Florence
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