Karolinska Institutet

Address
Nobels Vag 6

Sponsor Overview

assignment
29
sponsored trials
science
63
molecules
location_city
89
research centres
public
8
countries
person_search
183
investigators

Specializations

Cardiovascular and Renal Medicine

Clinical research includes heart failure with reduced ejection fraction, severe chronic kidney disease, acute myocardial infarction, and left ventricular thrombosis, with additional interest in treatment strategies for acute ischaemic stroke.

  • Heart failure
  • Chronic kidney disease
  • Myocardial infarction
  • Stroke
  • Thromboembolic disease

Work in this area also extends to anticoagulation, biomarker-informed treatment selection, and cardiovascular complications after major cardiac events.

Oncology and Haematology

The sponsor supports studies in breast cancer, colorectal cancer, prostate cancer, multiple myeloma, acute myeloid leukaemia, and glioblastoma, together with hereditary cancer risk in Lynch syndrome.

  • Breast malignancies
  • Colorectal neoplasia
  • Prostate cancer
  • Blood cancers
  • Brain tumours

Research interests include treatment optimisation, maintenance approaches, recurrence prevention, and precision-medicine strategies linked to tumour biology.

Immunology, Allergy, and Infectious Disease

Trials address allergic rhinitis, dog allergy, grass pollen allergy, rheumatoid arthritis, RSV infection, and Crimean-Congo haemorrhagic fever, reflecting a broad focus on immune-mediated and infectious conditions.

  • Allergic disease
  • Autoimmune inflammation
  • Respiratory viral infection
  • Viral haemorrhagic fever
  • Allergen-specific immunotherapy

Additional areas include immune modulation, vaccine-related responses, and symptom control in chronic inflammatory disease.

Neurology, Psychiatry, and Cognitive Health

Research activity covers Alzheimer’s disease, major depressive disorder, alcohol use disorder, and neurorehabilitation after stroke, alongside studies in pain-related neuromuscular conditions.

  • Neurodegenerative disease
  • Depression
  • Addiction medicine
  • Brain injury recovery
  • Temporomandibular disorders

There is also interest in cognitive function, behavioural outcomes, and treatment-related neurological effects.

Women’s Health, Reproductive Medicine, and Musculoskeletal Disorders

Clinical studies include polycystic ovary syndrome, ectopic pregnancy, post-abortion contraception, sexual function after cancer treatment, and skeletal conditions such as osteogenesis imperfecta.

  • Reproductive health
  • Contraception
  • Sexual medicine
  • Bone fragility disorders
  • Dental bone regeneration

Related research also includes fertility-adjacent care, hormonal treatment effects, and supportive procedures in oral surgery.

Sponsored Trials

Trial Name Country Status
A Phase I/II Study to Evaluate the Safety and Efficacy of CAT-01 in Patients with Advanced Cervical CarcinomaSweden SwedenNot Yet Recruiting
Comparative Efficacy of Apixaban Versus Warfarin in Thrombus Resolution for Patients with Left Ventricular Thrombosis Post-Acute Myocardial InfarctionDenmark DenmarkSweden SwedenRecruiting
Efficacy of Imatinib in Acute Ischemic Stroke: A Phase 3 Randomized, Double-Blind, Placebo-Controlled TrialSweden SwedenNot Yet Recruiting
Evaluation of Acupuncture and Metformin Hydrochloride on Insulin Sensitivity in Women with Polycystic Ovary Syndrome: A Randomized Controlled TrialSweden SwedenRecruiting
Evaluation of Alutard SQ Dog in Dog-Allergic Patients with Allergic Rhinitis: A Study on Efficacy and Symptom Improvement in Swedish Clinical PracticeSweden SwedenNot Yet Recruiting
Evaluation of Botulinum Toxin A on Gene Expression and Cellular Plasticity in Myogenous Temporomandibular DisordersSweden SwedenRecruiting
Evaluation of Eplerenone, Altizide, and Micronised Spironolactone in Heart Failure with Reduced Ejection Fraction and Severe Chronic Kidney DiseaseSweden SwedenNot Yet Recruiting
Evaluation of Immediate Versus Delayed Intrauterine Levonorgestrel Insertion Post-Medical Abortion: A Randomized Multicenter StudySweden SwedenNot Yet Recruiting
Evaluation of Intralymphatic Immunotherapy Enhanced by Vitamin D in Patients with Moderate to Severe Allergic Rhinitis: A Randomized, Placebo-Controlled StudySweden SwedenNot Recruiting
Evaluation of Mesalazine for Colorectal Neoplasia Prevention in Lynch Syndrome: A Randomized, Placebo-Controlled TrialDenmark DenmarkSweden SwedenNot Recruiting
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Data & Insights

science
Molecule Portfolio
Compounds under investigation
2
Exclusive Molecules
out of 63 total (3% not shared with other sponsors)

This sponsor works with 63 molecules, of which 2 are not being studied by other sponsors.

hub
Site Partnerships
Collaboration with research centres
36%
Return partnership rate
32 of 89 sites collaborated multiple times

This sponsor has worked with 89 sites across their trial portfolio.

Therapeutic Focus

  • 1.
    Neoplasms8 trials
    853 other sponsors
  • 2.
    Cardiovascular Diseases3 trials
    359 other sponsors
  • 3.
    Female Urogenital Diseases and Pregnancy Complications3 trials
    142 other sponsors
  • 4.
    Not possible to specify3 trials
    220 other sponsors
  • 5.
    Virus Diseases3 trials
    182 other sponsors
  • 6.
    Congenital, Hereditary, and Neonatal Diseases and Abnormalities2 trials
    165 other sponsors
  • 7.
    Hemic and Lymphatic Diseases2 trials
    249 other sponsors
  • 8.
    Immune System Diseases2 trials
    322 other sponsors
  • 9.
    Musculoskeletal Diseases2 trials
    238 other sponsors
  • 10.
    Bacterial Infections and Mycoses1 trial
    180 other sponsors
  • 11.
    Behavior and Behavior Mechanisms1 trial
    38 other sponsors
  • 12.
    Digestive System Diseases1 trial
    280 other sponsors
  • 13.
    Hormonal diseases1 trial
    89 other sponsors
  • 14.
    Mental Disorders1 trial
    150 other sponsors
  • 15.
    Nervous System Diseases1 trial
    449 other sponsors
  • 16.
    Respiratory Tract Diseases1 trial
    277 other sponsors
  • 17.
    Therapeutics1 trial
    87 other sponsors

Partnered Research Centres

89 centres
location_city
assignment335
Aalborg University Hospital
Address
Moelleparkvej 4, 9000 Aalborg
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location_city
assignment352
Aarhus University Hospital
Address
Palle Juul-Jensens Boulevard 99, 8200 Aarhus
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location_city
assignment2
Akademiska sjukhuset
Address
Akademiska sjukhuset, 751 85 Uppsala
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location_city
assignment185
Akershus University Hospital
Address
Sykehusveien 25, 1474 Lorenskog
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location_city
assignment25
Algemeen Ziekenhuis Damiaan Oostende
Address
Gouwelozestraat 100, 8400 Ostend
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location_city
assignment163
Algemeen Ziekenhuis Groeninge
Address
President Kennedylaan 4, 8500 Kortrijk
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