Johns Hopkins University
- Address
- 3400 North Charles Street
Sponsor Overview
Specializations
Inherited Retinal Disease
Research activity centers on retinitis pigmentosa, a progressive retinal dystrophy associated with gradual loss of visual function and increasing visual disability.
- Retinitis pigmentosa
- Retinal degeneration
- Visual function preservation
The sponsor’s clinical focus in this area is directed toward maintaining vision and addressing the long-term burden of inherited retinal impairment.
Ophthalmic Therapeutics
Clinical interest includes oral antioxidant therapy for eye disease, with attention to treatment options that may support retinal health and visual stability.
- N-acetylcysteine
- Antioxidant treatment
- Visual disability reduction
This area reflects a therapeutic emphasis on interventions for chronic ophthalmologic conditions with unmet needs in vision preservation.
Long-Term Safety and Tolerability
Research also addresses the extended use of therapies in patients with chronic eye disease, with attention to tolerability and sustained treatment exposure over time.
- Long-term safety
- Tolerability assessment
- Chronic treatment management
The clinical scope includes monitoring how ongoing therapy is received in patients living with progressive retinal disease.
Multicenter Clinical Collaboration
The funded research spans multiple collaborating sites across several countries, supporting coordinated investigation in ophthalmology and inherited eye disorders.
- Multicenter research
- International site collaboration
- Recruiting clinical study
This networked structure supports access to patients with rare retinal conditions and broadens the clinical reach of the sponsor’s eye-disease portfolio.
Sponsored Trials
| Trial Name | Country | Status |
|---|---|---|
| NAC Attack, A Phase III, Multicenter, Randomized, Parallel, Double Masked, Placebo-Controlled Study Evaluating the Efficacy and Safety of Oral N-Acetylcysteine in Patients with Retinitis Pigmentosa |  Austria Germany The Netherlands | Not Recruiting |
Data & Insights
This sponsor works with 1 molecule, of which 0 are not being studied by other sponsors.
This sponsor has worked with 4 sites across their trial portfolio.
Therapeutic Focus
- 1.Eye Diseases1 trial138 other sponsors
Partnered Research Centres
4 centres- Address
- Meibergdreef 9, 1105 AZ Amsterdam
- Address
- Neue Stiftingtalstrasse 6, 8010 Graz
- Address
- Geert Grooteplein Zuid 10, 6525 GA Nijmegen
- Address
- Otfried-Mueller-Strasse 10, Nordstadt, 72076 Tübingen
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