Istituto Biochimico Italiano Giovanni Lorenzini S.p.A.
- Address
- Via Fossignano 2
Sponsor Overview
Specializations
Endocrinology and Adrenal Disorders
The sponsor’s clinical research is centered on Cushing’s disease, with attention to disorders of cortisol excess and the management of hypercortisolism.
- Endocrine disease
- Adrenal gland dysfunction
- Cortisol dysregulation
Its research activity in this field reflects a focused interest in conditions driven by abnormal hormonal regulation and related metabolic consequences.
Rare Disease Therapeutics
The sponsor is involved in the study of a rare endocrine disorder affecting patients with active Cushing’s disease, supporting therapeutic development in an area of limited treatment options.
- Orphan disease care
- Specialized endocrine treatment
- Unmet medical need
This area of interest highlights work directed toward clinical problems that require targeted management within specialist endocrine practice.
Metabolic and Hormonal Regulation
Research activity also aligns with the broader consequences of excess glucocorticoid exposure, including disturbances in metabolism and systemic hormonal balance.
- Glucocorticoid excess
- Hormone homeostasis
- Endocrine metabolism
The clinical focus remains on disease processes where abnormal adrenal hormone activity is central to patient burden.
Clinical Pharmacology in Endocrine Care
The sponsor’s research includes evaluation of an investigational therapy for controlling excess cortisol secretion in active Cushing’s disease, placing emphasis on therapeutic intervention in endocrine medicine.
- Therapeutic endocrine intervention
- Cortisol-lowering treatment
- Medication development
This area reflects interest in treatments aimed at restoring more normal cortisol physiology in patients with persistent disease activity.
Sponsored Trials
| Trial Name | Country | Status |
|---|---|---|
| Evaluation of Silibinin Efficacy and Safety in Active Cushing's Disease: A Multicenter, Open-Label, Dose-Titration Study |  Italy | Not Recruiting |
Data & Insights
This sponsor works with 1 molecule, of which 1 is not being studied by other sponsors.
This sponsor has worked with 5 sites across their trial portfolio.
Therapeutic Focus
- 1.Hormonal diseases1 trial89 other sponsors
Partnered Research Centres
5 centres- Address
- Via Consolare Valeria N 1, 98124 Messina
- Address
- Via Nicolo' Giustiniani 2, 35128 Padua
- Address
- Via Cherasco 15, 10126 Turin
- Address
- Via Di Grottarossa 1035-1039, 00189 Rome
- Address
- Largo Francesco Vito 1, 00168 Rome
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