Instituto Grifols S.A.
- Address
- Calle De Can Guasch 2, Poligono Industrial Llevant
Sponsor Overview
Specializations
Hepatology and Acute-on-Chronic Liver Failure
Research activity is centered on cirrhosis complicated by acute-on-chronic liver failure, including patients identified with ACLF-1b, ACLF-2, and ACLF-3a during admission or hospitalization.
- Liver failure
- Cirrhosis
- Hospital mortality
The sponsor’s clinical interest is focused on severe hepatic decompensation and outcomes in patients at high risk of death during acute liver deterioration.
Critical Care and Inpatient Survival
The funded trial addresses survival in hospitalized patients with advanced liver disease, reflecting interest in conditions managed within acute care and intensive monitoring settings.
- Hospitalized patients
- Severe systemic illness
- Short-term survival
Clinical attention is directed toward outcomes measured over the 90-day period following acute deterioration in the setting of chronic liver disease.
Blood-Based Therapeutics and Plasma-Derived Treatment
The research portfolio includes evaluation of plasma-derived supportive treatment alongside standard medical care in severe liver disease.
- Plasma therapy
- Supportive treatment
- Adjunctive care
This area links the sponsor’s clinical work to therapies used in liver support and management of complex inpatient complications.
Multinational Clinical Research
The sponsor is involved in a geographically distributed trial network spanning multiple countries and collaborating sites, with activity across Europe and other regions.
- International recruitment
- Collaborative sites
- Cross-border study conduct
Its clinical research activity is concentrated in a single ongoing study with broad site participation for patients with advanced liver disease.
Sponsored Trials
| Trial Name | Country | Status |
|---|---|---|
| Effects of Plasma Exchange with Human Serum Albumin 5% (PE-A 5%) on Short-term Survival in Subjects with Acute-On-Chronic Liver Failure" (ACLF) at High Risk of Hospital Mortality |  Austria Belgium Bulgaria Croatia France Germany Hungary Italy Poland Romania Spain | Not Recruiting |
Data & Insights
This sponsor works with 1 molecule, of which 0 are not being studied by other sponsors.
This sponsor has worked with 33 sites across their trial portfolio.
Therapeutic Focus
- 1.Digestive System Diseases1 trial280 other sponsors
Partnered Research Centres
33 centres- Address
- Konstantin Pomyanov Str 1, 1415 Sofia
- Address
- Piazza Dell'ospedale Maggiore 3, 20162 Milan
- Address
- Via Nicolo' Giustiniani 2, 35128 Padua
- Address
- Avenija Gojka Suska 6, Zagreb, 10000 Zagreb
- Address
- Europska Avenija 14, 31000 Osijek
- Address
- Strada Marinescu Gheorghe 50, 540136 Târgu Mureş
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