Institute Of Tropical Medicine

The sponsor investigates how antibiotic exposure influences Escherichia coli susceptibility in the gastrointestinal tract, with attention to shifts in minimum inhibitory concentration patterns and the emergence of reduced susceptibility after prophylactic use.

• Escherichia coli resistance patterns
• ciprofloxacin exposure and bacterial susceptibility
• rectal E. coli and doxycycline resistance

Work in this area links antibiotic prevention strategies with changes in commensal and colonising bacteria.

Clinical research includes rabies prevention, comparing intradermal and intramuscular vaccination routes, pre-exposure prophylaxis schedules, and booster responses measured through rabies antibodies and skin-resident memory T cells.

• rabies pre-exposure prophylaxis
• intradermal and intramuscular vaccination routes
• booster immunogenicity and skin imprinting

Additional work includes vaccination experiences in children, with attention to pain and usability of injection techniques.

The sponsor also studies yellow fever immunisation, comparing intradermal, subcutaneous, and intramuscular routes, with emphasis on immune imprinting and the generation of yellow fever virus-specific memory responses.

• yellow fever vaccination routes
• skin-resident memory T cells
• vaccination immunogenicity

These studies support understanding of route-dependent immune responses in traveller and preventive medicine contexts.

Research activity extends to the reduction of craving and use of chemsex-related drugs, combining pharmacological and counselling-based approaches in adults affected by problematic stimulant and related substance use.

• chemsex-associated drug craving
• semaglutide in behavioural support
• counselling for substance-use reduction

This area connects sexual health with interventions targeting substance-related risk behaviour.