Iecure Inc.
- Address
- 1777 Sentry Parkway West Suite 200 Building 14
Sponsor Overview
Specializations
Urea Cycle Disorders
Clinical research is centered on ornithine transcarbamylase deficiency (OTC deficiency), with attention to the metabolic consequences of impaired ammonia detoxification in early-onset disease.
- Neonatal-onset OTC deficiency
- Inherited metabolic disease
- Ammonia metabolism
Interest is focused on pediatric patients with severe urea cycle dysfunction, particularly in the setting of early-life presentation.
Pediatric Genetic Medicine
The sponsor’s clinical activity involves treatment areas relevant to infants with rare genetic disorders, especially conditions presenting in the first months of life.
- Male infants
- Early-onset inherited disease
- Monogenic metabolic disorders
This area reflects a focus on severe pediatric disease burden where disease expression begins shortly after birth.
Gene-Based Therapeutics
Research activity includes ECUR-506 within a therapeutic context aligned to genetic intervention for metabolic disease, with emphasis on restoring function in the affected pathway.
- Genetic correction
- Targeted molecular therapy
- Hepatic metabolic function
The therapeutic interest is directed toward disease-modifying approaches for inherited enzyme deficiency.
Hepatic Metabolism and Ammonia Control
Clinical interest extends to the liver-based metabolic pathway responsible for converting nitrogen waste, a central issue in hyperammonemia management.
- Nitrogen disposal
- Metabolic detoxification
- Ammonia-related toxicity
These areas are closely linked to preventing the neurological and systemic effects associated with disrupted urea cycle activity.
Sponsored Trials
| Trial Name | Country | Status |
|---|---|---|
| Evaluation of Safety and Efficacy of ECUR-506A and ECUR-506D in Male Infants with Neonatal Onset Ornithine Transcarbamylase Deficiency |  Spain | Not Recruiting |
| Long-Term Safety Follow-Up of AAV‑RH79‑OTC Gene Therapy (ECUR‑506D) in Patients with Ornithine Transcarbamylase Deficiency |  France Spain | Recruiting |
Data & Insights
This sponsor works with 1 molecule, of which 1 is not being studied by other sponsors.
This sponsor has worked with 3 sites across their trial portfolio.
Therapeutic Focus
- 1.Congenital, Hereditary, and Neonatal Diseases and Abnormalities2 trials165 other sponsors
Partnered Research Centres
3 centres- Address
- 165 Chemin Du Grand Revoyet, 69310 Pierre Benite
- Address
- Passeig De Sant Joan De Deu 2, 08950 Esplugues de Llobregat
- Address
- Avenida De Cordoba Sn, 28041 Madrid
Want to get in touch with this sponsor?
Send a question and we'll pass it on to Iecure Inc..
Need a custom report on this sponsor?
Competitive positioning, market entry, partnership opportunities — tell us the question.
Is something out of date?
Tell us what needs correcting and we'll update this profile.