Fondazione Italiana Sclerosi Multipla Ente Del Terzo Settore/et S
- Address
- Via Operai 40
Sponsor Overview
Specializations
Multiple Sclerosis and Neuroinflammatory Disease
Clinical research is concentrated on relapsing-remitting multiple sclerosis, with attention to disease activity, lesion burden, and long-term control of inflammatory progression.
- Multiple sclerosis disease activity
- Relapsing-remitting multiple sclerosis
- Magnetic resonance imaging lesion monitoring
Interest extends to outcomes linked with sustained absence of clinical and radiological activity, including NEDA-3 as a key therapeutic endpoint.
Radiologically Isolated Syndrome
Research activity also includes radiologically isolated syndrome, focusing on early identification of individuals at risk of developing symptomatic demyelinating disease.
- Radiologically isolated syndrome
- Early demyelinating disease
- MRI-based risk assessment
Therapeutic interest in this area centers on imaging markers of new inflammatory activity and the transition from incidental findings to clinically manifest disease.
Autologous Haematopoietic Stem Cell Transplantation
The sponsor supports research in aggressive multiple sclerosis involving autologous haematopoietic stem cell transplantation as a treatment strategy for difficult-to-control disease.
- Autologous haematopoietic stem cell transplantation
- Aggressive multiple sclerosis
- Disease remission
Relevant outcomes include sustained suppression of disease activity and achievement of no evidence of disease activity over extended follow-up.
Immunomodulation and Vaccine-Based Approaches
Another area of interest is immunomodulatory therapy, including vaccine-based strategies explored in relation to early multiple sclerosis risk and immune response modulation.
- Immunomodulation
- Vaccine-based therapy
- Immune response modulation
This reflects a focus on interventions that may influence inflammatory pathways and alter the course of central nervous system autoimmunity.
Sponsored Trials
Data & Insights
This sponsor works with 15 molecules, of which 1 is not being studied by other sponsors.
This sponsor has worked with 24 sites across their trial portfolio.
Therapeutic Focus
- 1.Nervous System Diseases2 trials449 other sponsors
Partnered Research Centres
24 centres- Address
- Piazza Nicola Leotta 4, 90127 Palermo
- Address
- Via Sergio Pansini 5, 80131 Naples
- Address
- Strada Delle Scotte 14, 53100 Siena
- Address
- Piazza Luigi Miraglia 2, 80138 Naples
- Address
- Largo Giovanni Alessandro Brambilla 3, 50134 Florence
- Address
- Piazzale Giulio Cesare 11, 70124 Bari
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