Fondation A De Rothschild

Address
29 Rue Manin

Sponsor Overview

assignment
12
sponsored trials
science
22
molecules
location_city
41
research centres
public
1
country
person_search
83
investigators

Specializations

Stroke and Neurovascular Disorders

Clinical research in acute ischemic stroke, ischemic stroke with large core, and subarachnoid hemorrhage includes work on reperfusion, arterial recanalization, and functional recovery. The portfolio also covers cerebral arteriovenous malformations and treatment strategies for patients not eligible for interventional procedures.

  • Endovascular therapy
  • Mechanical thrombectomy
  • Recanalization
  • Functional outcome

These studies reflect a strong interest in acute cerebrovascular care and vascular brain injury.

Ophthalmology and Retinal Disease

The sponsor supports research in Coats' disease, central retinal vein occlusions, and severe ocular surface injury, with attention to vision preservation and retinal vascular pathology. Trials also address inflammatory and angiogenic mechanisms affecting ocular outcomes.

  • Anti-VEGF therapy
  • Intravitreal treatment
  • Ocular surface burns
  • Visual acuity

Research activity in this area spans both urgent eye injury care and chronic retinal disorders.

Neuroimmunology and Autoimmune Neurological Disease

Studies in multiple sclerosis and myasthenia gravis focus on disease control, relapse prevention, and suppression of neurological activity. The research also includes strategies aimed at limiting progression from ocular symptoms to generalized disease.

  • Disease activity
  • Immunotherapy
  • Relapse prevention
  • Radiological monitoring

This area connects chronic autoimmune neurology with longer-term management of inflammatory nervous system disorders.

Epilepsy and Seizure Control

Research in focal epilepsy addresses seizure recurrence during medication adjustment and perioperative monitoring. The sponsor’s activity in this field is centered on improving seizure suppression in patients undergoing specialized neurological evaluation.

  • Cluster seizures
  • Anti-seizure medication
  • Video EEG monitoring
  • Seizure recurrence

These trials place emphasis on seizure stability in complex clinical settings.

Alzheimer's Disease and Neurodegeneration

The portfolio also includes studies in Alzheimer's disease involving interventions aimed at modifying neurological progression and supporting cognitive care. This area broadens the sponsor’s interest to chronic neurodegenerative conditions.

  • Cognitive decline
  • Neuroinflammation
  • Brain imaging
  • Neurological progression

Research in this field aligns with efforts to address long-term central nervous system disease burden.

Sponsored Trials

Trial Name Country Status
Efficacy of Annual vs. Semi-Annual Ocrelizumab Infusions on Radiological Disease Activity in Active Multiple Sclerosis: A Randomized Non-Inferiority TrialFrance FranceRecruiting
Efficacy of Intravenous Glenzocimab in Patients with Anterior Ischemic Stroke and Large Core Eligible for Endovascular TherapyFrance FranceNot Recruiting
Efficacy of Intravitreal Bevacizumab as Initial and Adjuvant Therapy in Coats' Disease: A Multicenter Randomized Controlled TrialFrance FranceNot Recruiting
Evaluation of Bevacizumab Efficacy and Safety in Patients with Symptomatic Cerebral Arteriovenous Malformations Ineligible for Interventional TherapyFrance FranceRecruiting
Evaluation of Cangrelor Tetrasodium with Mechanical Thrombectomy in Perfusion Imaging-Selected Acute Ischemic Stroke Patients: A Multicenter Randomized Controlled TrialFrance FranceRecruiting
Evaluation of Corticosteroids and Rituximab in Preventing Generalization in Ocular Myasthenia Gravis: A Multicenter Randomized Controlled TrialFrance FranceRecruiting
Evaluation of Intravenous Dornase Alfa for Functional Independence Post-Subarachnoid Hemorrhage: A Multicenter Randomized Controlled TrialFrance FranceRecruiting
Evaluation of Probenecid Efficacy on Cluster Seizures During Anti-Seizure Medication Tapering in Presurgical Focal Epilepsy Video-EEG MonitoringFrance FranceNot Yet Recruiting
Evaluation of Spontaneous Retinal Arterial Pulsations as Prognostic Indicators in Central Retinal Vein Occlusion with Aflibercept TreatmentFrance FranceNot Recruiting
Phase I Evaluation of Etanercept and Repeated Contrast Ultrasound Safety in Alzheimer’s Disease PatientsFrance FranceRecruiting
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Data & Insights

science
Molecule Portfolio
Compounds under investigation
0
Exclusive Molecules
out of 22 total (0% not shared with other sponsors)

This sponsor works with 22 molecules, of which 0 are not being studied by other sponsors.

hub
Site Partnerships
Collaboration with research centres
44%
Return partnership rate
18 of 41 sites collaborated multiple times

This sponsor has worked with 41 sites across their trial portfolio.

Therapeutic Focus

  • 1.
    Nervous System Diseases7 trials
    449 other sponsors
  • 2.
    Eye Diseases3 trials
    138 other sponsors
  • 3.
    Cardiovascular Diseases2 trials
    359 other sponsors
  • 4.
    Immune System Diseases2 trials
    322 other sponsors
  • 5.
    Surgical Procedures, Operative1 trial
    58 other sponsors

Partnered Research Centres

41 centres
location_city
assignment966
Assistance Publique Hopitaux De Marseille
Address
264 Rue Saint Pierre, 13005 Marseille
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location_city
assignment444
Besancon University Hospital Center
Address
3 Boulevard Alexandre Fleming, 25000 Besançon
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location_city
assignment447
Centre Hospitalier Et Universitaire De Limoges
Address
2 Avenue Martin Luther King, 87000 Limoges
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location_city
assignment16
Centre Hospitalier General
Address
2 Boulevard Du 19 Mars 1962, 95500 Gonesse
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location_city
assignment37
Centre Hospitalier Intercommunal De Poissy Saint Germain
Address
20 Rue Armagis, Bp 231, 78104 St Germain En Laye
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location_city
assignment1199
Centre Hospitalier Lyon Sud
Address
165 Chemin Du Grand Revoyet, 69310 Pierre Benite
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