F. Hoffmann-La Roche AG
- Address
- Grenzacherstrasse 124
Sponsor Overview
Specializations
Oncology
F. Hoffmann-La Roche AG funds a broad oncology portfolio spanning breast cancer, non-small cell lung cancer, small cell lung cancer, hepatocellular carcinoma, colorectal cancer, and urothelial carcinoma, with additional activity in lymphoma, multiple myeloma, and other solid tumours.
- Breast cancer
- Non-small cell lung cancer
- Lymphoma
- Hepatocellular carcinoma
- Urothelial carcinoma
Its oncology research also includes biomarker-defined disease groups such as HER2-positive, hormone receptor-positive, PIK3CA-mutated, KRAS G12C-mutated, and ALK-rearranged cancers.
Neurology
The sponsor maintains strong interest in neurological disease, particularly multiple sclerosis across relapsing, progressive, and primary progressive forms, as well as Alzheimer’s disease, Parkinson’s disease, Huntington’s disease, Angelman syndrome, and spinal muscular atrophy.
- Multiple sclerosis
- Alzheimer’s disease
- Parkinson’s disease
- Huntington’s disease
- Spinal muscular atrophy
Research also extends to neuromyelitis optica spectrum disorder, myelin oligodendrocyte glycoprotein antibody-associated disease, and autoimmune encephalitis.
Immunology and Inflammatory Disease
Roche supports studies in rheumatoid arthritis, systemic lupus erythematosus, lupus nephritis, Crohn’s disease, ulcerative colitis, atopic dermatitis, asthma, and chronic obstructive pulmonary disease.
- Rheumatoid arthritis
- Systemic lupus erythematosus
- Crohn’s disease
- Ulcerative colitis
- Atopic dermatitis
Additional work covers thyroid eye disease, IgA nephropathy, primary membranous nephropathy, and paroxysmal nocturnal hemoglobinuria.
Ophthalmology and Vision Disorders
The sponsor is active in ophthalmology, with trials in neovascular age-related macular degeneration, choroidal neovascularization secondary to pathologic myopia, uveitic macular edema, and thyroid eye disease.
- Neovascular age-related macular degeneration
- Uveitic macular edema
- Choroidal neovascularization
- Thyroid eye disease
- Visual function
These studies include conditions affecting retinal and orbital inflammation, with attention to preserving visual acuity and related ocular outcomes.
Hematology, Metabolic, and Rare Diseases
Roche also funds research in hemophilia A, sickle cell disease, paroxysmal nocturnal hemoglobinuria, atypical hemolytic uremic syndrome, and selected kidney diseases such as primary IgA nephropathy and lupus nephritis.
- Hemophilia A
- Sickle cell disease
- Paroxysmal nocturnal hemoglobinuria
- Atypical hemolytic uremic syndrome
- Primary IgA nephropathy
Its broader programme includes obesity, type 2 diabetes mellitus, hepatic impairment, and studies in healthy volunteers to support development across therapeutic areas.
Sponsored Trials
Data & Insights
This sponsor works with 150 molecules, of which 28 are not being studied by other sponsors.
This sponsor has worked with 1308 sites across their trial portfolio.
Therapeutic Focus
- 1.Neoplasms103 trials853 other sponsors
- 2.Nervous System Diseases46 trials449 other sponsors
- 3.Immune System Diseases18 trials322 other sponsors
- 4.Hemic and Lymphatic Diseases16 trials249 other sponsors
- 5.Not possible to specify10 trials220 other sponsors
- 6.Eye Diseases9 trials138 other sponsors
- 7.Nutritional and Metabolic Diseases9 trials211 other sponsors
- 8.Immune System Phenomena8 trials15 other sponsors
- 9.Digestive System Diseases6 trials280 other sponsors
- 10.Environment and Public Health6 trials7 other sponsors
- 11.Musculoskeletal Diseases6 trials238 other sponsors
- 12.Population Characteristics5 trials3 other sponsors
- 13.Congenital, Hereditary, and Neonatal Diseases and Abnormalities4 trials165 other sponsors
- 14.Behavioral Disciplines and Activities3 trials20 other sponsors
- 15.Respiratory Tract Diseases2 trials277 other sponsors
- 16.Cardiovascular Diseases1 trial359 other sponsors
- 17.Chemical Phenomena1 trial2 other sponsors
- 18.Female Urogenital Diseases and Pregnancy Complications1 trial142 other sponsors
- 19.Immune system processes1 trial65 other sponsors
- 20.Male Urogenital Diseases1 trial111 other sponsors
- 21.Metabolism1 trial38 other sponsors
- 22.Skin and Connective Tissue Diseases1 trial247 other sponsors
Partnered Research Centres
1308 centres- Address
- Blagoevgrad Region, Blagoevgrad Municipality,, City of Blagoevgrad, 17 Aleko Konstantinov St, 2700 Blagoevgrad
- Address
- Via Fiorignano 1, 84091 Battipaglia
- Address
- Ul. Rudolfa Weigla 5, 53-114 Wroclaw
- Address
- Panagioti Kanellopoulou Av 1, 115 25 Athens
- Address
- Via Consolare Valeria N 1, 98124 Messina
- Address
- Moelleparkvej 4, 9000 Aalborg
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