Esperion Therapeutics Inc.

Address
3891 Ranchero Drive Suite 150

Sponsor Overview

assignment
1
sponsored trial
science
1
molecule
location_city
11
research centres
public
4
countries
person_search
13
investigators

Specializations

Familial Hypercholesterolemia

Esperion Therapeutics Inc. focuses on clinical research in heterozygous familial hypercholesterolemia, with an emphasis on inherited lipid disorders that require targeted management of elevated LDL cholesterol.

  • Heterozygous familial hypercholesterolemia
  • Inherited dyslipidemia
  • Cholesterol-lowering therapy

The sponsor’s research activity includes evaluation in pediatric patients and reflects interest in age-specific treatment considerations for children and adolescents living with this condition.

Paediatric Lipid Disorders

Clinical work supported by Esperion Therapeutics extends to children and adolescents with hypercholesterolemia, addressing therapeutic needs in younger populations affected by persistent lipid elevation.

  • Paediatric patients
  • Lipid metabolism
  • Age-appropriate cardiovascular risk reduction

Research in this area centers on treatment use in patients aged 6 to 17 years, highlighting interest in therapeutic options suitable for early-life management of inherited cholesterol disorders.

Cardiometabolic Therapeutics

The sponsor’s trial portfolio is aligned with cardiometabolic medicine, particularly therapies designed to address abnormal cholesterol handling and the long-term risk burden associated with atherosclerotic cardiovascular disease.

  • Atherosclerotic cardiovascular disease risk
  • Non-statin lipid management
  • Cholesterol biosynthesis and clearance

This area of interest connects lipid-focused treatment development with clinical care for patients whose genetic condition places them at increased cardiovascular risk.

Pharmacokinetic Evaluation

Esperion Therapeutics also shows interest in pharmacokinetics within its clinical studies, supporting understanding of how lipid-lowering therapy is handled in the body in younger patients with HeFH.

  • Drug absorption
  • Drug exposure
  • Paediatric pharmacology

These research activities are relevant to the development of therapies intended for inherited cholesterol disorders across different age groups.

Sponsored Trials

Trial Name Country Status
Pharmacokinetics, Pharmacodynamics, and Safety Evaluation of Bempedoic Acid in Pediatric Patients with Heterozygous Familial HypercholesterolemiaDenmark DenmarkGermany GermanySpain SpainThe Netherlands The NetherlandsNot Recruiting

Data & Insights

science
Molecule Portfolio
Compounds under investigation
0
Exclusive Molecules
out of 1 total (0% not shared with other sponsors)

This sponsor works with 1 molecule, of which 0 are not being studied by other sponsors.

hub
Site Partnerships
Collaboration with research centres
0%
Return partnership rate
0 of 11 sites collaborated multiple times

This sponsor has worked with 11 sites across their trial portfolio.

Therapeutic Focus

  • 1.
    Cardiovascular Diseases1 trial
    359 other sponsors

Partnered Research Centres

11 centres
location_city
assignment680
Amsterdam UMC
Address
De Boelelaan 1117, 1081 HV Amsterdam
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location_city
assignment1
Auf der Bult Kinder- und Jugendkrankenhaus
Address
Janusz-Korczak-Allee 12, 30173 Hanover
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location_city
assignment711
Erasmus Universitair Medisch Centrum Rotterdam (Erasmus MC)
Address
Dr. Molewaterplein 40, 3015 GD Rotterdam
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location_city
assignment620
Goethe University Frankfurt
Address
Theodor-Stern-Kai 7, 60590 Frankfurt
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location_city
assignment124
Hospital Jerez de la Frontera
Address
Carretera De La Ronda Circunvalacion S/n, 11407 Jerez de la Frontera
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location_city
assignment327
Hospital Sant Joan De Deu Barcelona
Address
Passeig De Sant Joan De Deu 2, 08950 Esplugues de Llobregat
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