Erasmus Universitair Medisch Centrum Rotterdam (Erasmus MC)

Address
Dr. Molewaterplein 40

Sponsor Overview

assignment
96
sponsored trials
science
179
molecules
location_city
146
research centres
public
14
countries
person_search
439
investigators

Specializations

Oncology and Tumour-Directed Therapy

Oncology research spans solid and haematological malignancies, with strong activity in pancreatic cancer, colorectal cancer, gastro-oesophageal cancer, cholangiocarcinoma, urothelial cancer, prostate cancer, breast cancer, melanoma, glioblastoma, and paediatric leukaemia.

  • Peritoneal metastases
  • Targeted therapy and immunotherapy
  • Image-guided surgery and PET imaging
  • Radiotherapy combinations
  • Paediatric and adult cancer care

Work in this area also includes neuroendocrine tumours, sarcomas, head and neck cancer, and carcinoma of unknown primary.

Neurology, Pain, and Neuroimmunology

Clinical research covers migraine, anti-NMDAR encephalitis, neuromyelitis optica spectrum disorder, autism spectrum disorder, and complex regional pain syndrome, alongside studies in glioma and other central nervous system disorders.

  • Headache and trigeminovascular biology
  • Autoimmune encephalitis
  • Neuropathic pain
  • Neuro-oncology
  • Neurodevelopmental disorders

Additional interest extends to epilepsy-related and inflammatory neurological conditions.

Cardiovascular, Renal, and Metabolic Medicine

Research includes atherosclerosis, cardiogenic shock, aortic stenosis, coronary artery disease, cardiac sarcoidosis, and high cardiovascular risk populations, as well as kidney transplantation and autosomal dominant polycystic kidney disease.

  • Transcatheter valve care
  • Antithrombotic treatment selection
  • Tacrolimus optimisation
  • Lipid-lowering therapy
  • Renal physiology and hemodialysis

Metabolic interests also include obesity, statin intolerance, and muscle protein turnover.

Autoimmune, Inflammatory, and Infectious Diseases

Investigations address rheumatoid arthritis, psoriatic arthritis, Crohn's disease, pulmonary sarcoidosis, Graves' orbitopathy, chronic hepatitis B, and HIV-1, with broader activity in immune-mediated and inflammatory disorders.

  • Biologic and immunomodulatory treatment
  • Inflammatory bowel disease
  • Endocrine autoimmunity
  • Vaccine response
  • Viral latency research

Work also includes sepsis and other critical care infection-related conditions.

Paediatrics, Surgery, and Perioperative Care

Clinical studies involve paediatric oncology, congenital gastrointestinal disorders, orthopaedic developmental conditions, esophageal atresia, postoperative pancreatic fistulas, and perioperative coagulation management.

  • Paediatric transplant and drug monitoring
  • Fluorescence-guided surgery
  • Hepatic arterial infusion and intraperitoneal therapy
  • Orthopaedic and musculoskeletal disorders
  • Perioperative blood management

Research further covers quality of life, exercise capacity, and supportive care in surgical and chronic disease settings.

Sponsored Trials

Trial Name Country Status
A Randomized Controlled Trial Comparing Methotrexate and Prednisone as First-Line Therapy in Patients with Pulmonary SarcoidosisThe Netherlands The NetherlandsRecruiting
A Randomized, Double-Blind, Cross-Over Trial Assessing Rosuvastatin Calcium and Placebo in Statin-Intolerant Patients with High Cardiovascular RiskThe Netherlands The NetherlandsRecruiting
Accuracy of 68Ga-Pentixafor PET/CT for the Imaging of Cardiac Sarcoidosis: The ASPECT StudyThe Netherlands The NetherlandsNot Yet Recruiting
Bioequivalence Study of Rosuvastatin 10 mg in Healthy VolunteersThe Netherlands The NetherlandsNot Recruiting
Chronotherapy in Rheumatoid and Psoriatic Arthritis: A Randomized Controlled Trial of Tofacitinib Extended-Release Morning vs. Evening DosingThe Netherlands The NetherlandsRecruiting
Comparison of Coagulation Outcomes Using Fresh Frozen Plasma Versus Solvent-Detergent Plasma in Pediatric Congenital Heart SurgeryThe Netherlands The NetherlandsRecruiting
Comparison of Perioperative and Adjuvant mFOLFIRINOX Regimens in Patients with Resectable Non-Metastatic Pancreatic CancerSweden SwedenThe Netherlands The NetherlandsNot Yet Recruiting
Dose Optimization of Nivolumab in Patients with Melanoma or Renal Cell Carcinoma Exhibiting Complete, Partial, or Stable ResponseThe Netherlands The NetherlandsNot Yet Recruiting
Efficacy and Safety of Corticosteroid Injections for the Treatment of Achilles Tendinopathy: A Clinical StudyThe Netherlands The NetherlandsRecruiting
Efficacy of Adjuvant Hepatic Arterial Infusion of Floxuridine Post-Resection in Low-Risk Resectable Colorectal Liver Metastases: A Randomized Controlled TrialThe Netherlands The NetherlandsNot Yet Recruiting
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Data & Insights

science
Molecule Portfolio
Compounds under investigation
10
Exclusive Molecules
out of 179 total (6% not shared with other sponsors)

This sponsor works with 179 molecules, of which 10 are not being studied by other sponsors.

hub
Site Partnerships
Collaboration with research centres
46%
Return partnership rate
67 of 146 sites collaborated multiple times

This sponsor has worked with 146 sites across their trial portfolio.

Therapeutic Focus

  • 1.
    Neoplasms42 trials
    853 other sponsors
  • 2.
    Digestive System Diseases10 trials
    280 other sponsors
  • 3.
    Musculoskeletal Diseases8 trials
    238 other sponsors
  • 4.
    Nervous System Diseases8 trials
    449 other sponsors
  • 5.
    Therapeutics8 trials
    87 other sponsors
  • 6.
    Cardiovascular Diseases6 trials
    359 other sponsors
  • 7.
    Virus Diseases5 trials
    182 other sponsors
  • 8.
    Hormonal diseases4 trials
    89 other sponsors
  • 9.
    Immune System Diseases4 trials
    322 other sponsors
  • 10.
    Diagnosis3 trials
    83 other sponsors
  • 11.
    Female Urogenital Diseases and Pregnancy Complications3 trials
    142 other sponsors
  • 12.
    Male Urogenital Diseases3 trials
    111 other sponsors
  • 13.
    Not possible to specify3 trials
    220 other sponsors
  • 14.
    Nutritional and Metabolic Diseases3 trials
    211 other sponsors
  • 15.
    Skin and Connective Tissue Diseases3 trials
    247 other sponsors
  • 16.
    Congenital, Hereditary, and Neonatal Diseases and Abnormalities2 trials
    165 other sponsors
  • 17.
    Eye Diseases2 trials
    138 other sponsors
  • 18.
    Hemic and Lymphatic Diseases2 trials
    249 other sponsors
  • 19.
    Respiratory Tract Diseases2 trials
    277 other sponsors
  • 20.
    Surgical Procedures, Operative2 trials
    58 other sponsors
  • 21.
    Bacterial Infections and Mycoses1 trial
    180 other sponsors
  • 22.
    Cell Physiological Phenomena1 trial
    11 other sponsors
  • 23.
    Immune system processes1 trial
    65 other sponsors
  • 24.
    Mental Disorders1 trial
    150 other sponsors
  • 25.
    Pathological Conditions, Signs and Symptoms1 trial
    91 other sponsors
  • 26.
    Physiological processes1 trial
    28 other sponsors

Partnered Research Centres

146 centres
location_city
assignment2
's Heeren Loo
Address
Berkenweg 11, 3818 LA Berkenweg
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location_city
assignment38
Admiraal De Ruyter Ziekenhuis B.V.
Address
'S-Gravenpolderseweg 114, 4462 RA Goes
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location_city
assignment126
Albert Schweitzer Ziekenhuis
Address
Albert Schweitzerplaats 25, 3318 AT Dordrecht
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location_city
assignment283
Algemeen Ziekenhuis Delta
Address
Deltalaan 1, 8800 Roeselare
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location_city
assignment38
Alrijne Zorggroep Stichting
Address
Simon Smitweg 1, 2353 GA Leiderdorp
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location_city
assignment192
Amphia Hospital
Address
Molengracht 21, 4818 CK Breda
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