Centre Hospitalier Universitaire De Nantes

Address
5 Allee De L Ile Gloriette, Cs 69301

Sponsor Overview

assignment
52
sponsored trials
science
102
molecules
location_city
108
research centres
public
6
countries
person_search
399
investigators

Specializations

Hematologic Malignancies and Cellular Therapy

Acute myeloid leukemia, acute leukemia, multiple myeloma, and mantle cell lymphoma are central areas of interest, alongside transplant-linked care for high-risk blood cancers. The portfolio also includes studies in minimal residual disease assessment and allogeneic stem cell transplantation.

  • Acute myeloid leukemia
  • Multiple myeloma
  • Mantle cell lymphoma
  • Allogeneic stem cell transplantation
  • Minimal residual disease

Research activity extends to immune-based and transplant-adjacent approaches in patients with relapsed, refractory, or high-risk hematological disease.

Transplantation and Immunosuppression

The sponsor is active in kidney transplant, heart transplant, pancreatic transplant, and management of graft dysfunction and chronic renal failure. Work also covers immunosuppressive strategies and prevention of transplant-related complications.

  • Kidney transplant
  • Heart transplant
  • Pancreatic transplant
  • Graft dysfunction
  • Immunosuppression

Clinical research includes renal and cardiac graft preservation, rejection-related care, and post-transplant immune modulation.

Infectious Disease and Perioperative Care

Studies address hospital-acquired pneumonia, community-acquired pneumonia, MRSA, and staphylococcal endocarditis, with additional interest in perioperative infection control and antimicrobial selection. Surgical settings include cardiac, orthopedic, and transplant-related care.

  • Hospital-acquired pneumonia
  • Community-acquired pneumonia
  • MRSA
  • Staphylococcal endocarditis
  • Perioperative infection prevention

The research landscape also includes microbial decolonization, antifungal prophylaxis, and infection management in hospitalized adults.

Respiratory, Critical Care, and Emergency Medicine

Another major focus is severe asthma, traumatic brain injury, severe burns, and acute metabolic or respiratory instability requiring hospital-based intervention. The sponsor also supports work in hyperkalemia and urgent airway management.

  • Severe asthma
  • Traumatic brain injury
  • Severe burns
  • Hyperkalemia
  • Rapid sequence induction

These studies reflect interest in acute care pathways, critical illness, and treatment strategies for unstable patients in emergency and intensive care settings.

Autoimmune, Gastrointestinal, Pain, and Surgical Conditions

Research includes multiple sclerosis, atopic dermatitis, ulcerative colitis with recurrent pouchitis, severe primary dysmenorrhea, and postoperative pain syndromes. Surgical topics also include cardiac surgery, orthopedic trauma surgery, and shoulder arthroplasty.

  • Multiple sclerosis
  • Atopic dermatitis
  • Ulcerative colitis
  • Severe primary dysmenorrhea
  • Postoperative pain

Additional activity covers functional and behavioral conditions such as gambling disorder, as well as surgical infection prevention and pain control in complex procedures.

Sponsored Trials

Trial Name Country Status
A Randomized Controlled Trial on Fecal Microbiota Transplantation Versus Sodium Chloride for Recurrent Pouchitis in Ulcerative Colitis with IPAAFrance FranceNot Recruiting
BELASBRIDGE : Belatacept as a replacement for CNIs 3 to 12 months post-transplantation in patients with early graft dysfunctionFrance FranceNot Recruiting
Clindamycin as an alternative to vancomycin in patients undergoing aortic cardiac surgery with extracorporeal circulation (ECC): a prospective single-center pharmacokinetic study _ CLINDAPASSFrance FranceRecruiting
Comparative Efficacy of Insulin Aspart, Insulin Lispro, Glucose, and Salbutamol in Acute Hyperkalemia Management: A Randomized Clinical TrialFrance FranceNot Recruiting
Dupilumab step-down strategy to maintain remission in adult and adolescents patients with atopic dermatitis: a non-inferiority randomized trialFrance FranceNot Recruiting
Efficacy and safety of Remimazolam compared to Ketamine and Propofol in Rapid Sequence Induction. A monocentric pilot randomised-controlled studyFrance FranceNot Yet Recruiting
Efficacy of Dexamethasone Phosphate and Sodium Chloride in Severe Hospital-Acquired Pneumonia with Proinflammatory Phenotype: A Phase III Randomized TrialBelgium BelgiumFrance FranceGreece GreeceSpain SpainRecruiting
Efficacy of Ketamine, Propofol, and Ketamine-Propofol Combination for Rapid Sequence Induction in Patients at Risk of Aspiration: A Randomized Controlled TrialFrance FranceRecruiting
Evaluation of 18F-Fludarabine PET in Initial and Relapsed Assessment of Symptomatic Multiple Myeloma PatientsFrance FranceRecruiting
Evaluation of 89Zirconium-labelled Girentuximab PET-CT Imaging in Hepatocellular Carcinoma, Intrahepatic Cholangiocarcinoma, and Gastroenteropancreatic Neuroendocrine NeoplasmsFrance FranceNot Yet Recruiting
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Data & Insights

science
Molecule Portfolio
Compounds under investigation
7
Exclusive Molecules
out of 102 total (7% not shared with other sponsors)

This sponsor works with 102 molecules, of which 7 are not being studied by other sponsors.

hub
Site Partnerships
Collaboration with research centres
50%
Return partnership rate
54 of 108 sites collaborated multiple times

This sponsor has worked with 108 sites across their trial portfolio.

Therapeutic Focus

  • 1.
    Bacterial Infections and Mycoses7 trials
    180 other sponsors
  • 2.
    Hemic and Lymphatic Diseases7 trials
    249 other sponsors
  • 3.
    Not possible to specify6 trials
    220 other sponsors
  • 4.
    Anesthesia and Analgesia5 trials
    100 other sponsors
  • 5.
    Diagnosis4 trials
    83 other sponsors
  • 6.
    Pathological Conditions, Signs and Symptoms4 trials
    91 other sponsors
  • 7.
    Cardiovascular Diseases3 trials
    359 other sponsors
  • 8.
    Immune System Diseases3 trials
    322 other sponsors
  • 9.
    Behavior and Behavior Mechanisms2 trials
    38 other sponsors
  • 10.
    Digestive System Diseases2 trials
    280 other sponsors
  • 11.
    Neoplasms2 trials
    853 other sponsors
  • 12.
    Nervous System Diseases2 trials
    449 other sponsors
  • 13.
    Respiratory Tract Diseases2 trials
    277 other sponsors
  • 14.
    Skin and Connective Tissue Diseases2 trials
    247 other sponsors
  • 15.
    Surgical Procedures, Operative2 trials
    58 other sponsors
  • 16.
    Congenital, Hereditary, and Neonatal Diseases and Abnormalities1 trial
    165 other sponsors
  • 17.
    Female Urogenital Diseases and Pregnancy Complications1 trial
    142 other sponsors
  • 18.
    Hormonal diseases1 trial
    89 other sponsors
  • 19.
    Musculoskeletal Diseases1 trial
    238 other sponsors
  • 20.
    Nutritional and Metabolic Diseases1 trial
    211 other sponsors
  • 21.
    Stomatognathic Diseases1 trial
    16 other sponsors

Partnered Research Centres

108 centres
location_city
assignment57
Aix Marseille University
Address
264 Boulevard de Saint Pierre, 13005 Marseille
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location_city
assignment966
Assistance Publique Hopitaux De Marseille
Address
264 Rue Saint Pierre, 13005 Marseille
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location_city
assignment77
Assistance Publique Hopitaux De Paris
Address
27 Rue du Faubourg Saint-Jacques, 75014 Paris
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location_city
assignment478
Assistance Publique Hopitaux De Paris
Address
Num Voie 47 A 83, 47 Boulevard De L Hopital, 75013 Paris
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location_city
assignment18
Assistance Publique Hopitaux De Paris
Address
4 Rue De La Chine, 75020 Paris
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location_city
assignment444
Besancon University Hospital Center
Address
3 Boulevard Alexandre Fleming, 25000 Besançon
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