Centre Hospitalier Regional Universitaire

Address
2 Place Saint Jacques, Cs 51804

Sponsor Overview

assignment
14
sponsored trials
science
26
molecules
location_city
60
research centres
public
1
country
person_search
102
investigators

Specializations

Oncology and immunotherapy

The sponsor funds studies in hepatocellular carcinoma, biliary tract carcinoma, glioblastoma, colorectal cancer, and melanoma, with strong interest in immune checkpoint inhibition, therapeutic cancer vaccines, and combinations with anti-angiogenic therapy or chemotherapy.

  • Hepatocellular carcinoma
  • Glioblastoma
  • Colorectal cancer
  • Cutaneous melanoma
  • Biliary tract carcinoma

Research activity also includes metastatic disease, unresectable tumors, and neoadjuvant or maintenance immunotherapy strategies.

Digestive system and gastrointestinal cancer surgery

Clinical work in colorectal surgery and esophageal cancer focuses on surgical outcomes, perioperative support, and treatment intensification for advanced gastrointestinal malignancies, including anal canal cancer and esophageal carcinoma.

  • Colorectal surgery
  • Esophageal cancer
  • Anal canal cancer
  • Metastatic colorectal carcinoma

Topics include anastomotic integrity, chemoradiotherapy, and multimodal treatment for locally advanced digestive tumors.

Urologic oncology and renal transplantation

The sponsor supports research in penile squamous cell carcinoma and kidney transplantation, combining interest in cancer treatment with post-transplant care and immune-related complications.

  • Penile squamous cell carcinoma
  • Renal transplant
  • Post-transplant diabetes
  • Immunosuppression

Research also addresses lymphocyte depletion prevention and metabolic follow-up after transplantation.

Cardiology and heart failure

One area of interest is chronic decompensated heart failure in older adults, with attention to early treatment pathways in the emergency setting and cardiometabolic management.

  • Chronic decompensated heart failure
  • Emergency department care
  • Gliflozin therapy
  • Elderly patients

Work in this field connects cardiovascular disease with practical inpatient and outpatient care transitions.

Renal disease and metabolic complications

The sponsor is involved in studies of renal insufficiency and transplantation-related metabolic risk, including prevention of new-onset diabetes after kidney transplantation.

  • Renal insufficiency
  • Kidney transplantation
  • Post-transplant diabetes
  • Metabolic monitoring

These studies reflect interest in renal function, transplant follow-up, and endocrine complications in immunologically vulnerable patients.

Sponsored Trials

Trial Name Country Status
Evaluation of Avelumab Maintenance Immunotherapy Post-First-Line Platinum-Based Chemotherapy in Locally Advanced or Metastatic Squamous Cell Penile CarcinomaFrance FranceNot Recruiting
Evaluation of Intraoperative Indocyanine Green Fluorescence Angiography for Reducing Anastomotic Leakage in Colorectal Cancer SurgeryFrance FranceRecruiting
Evaluation of Optimal Dosing of Rabbit Anti-Human T-Lymphocyte Immunoglobulin and Mycophenolic Acid in Low Immunological Risk Renal Transplant RecipientsFrance FranceRecruiting
Evaluation of Regorafenib Combined with Metronomic Chemotherapy and Low-Dose Aspirin Versus Regorafenib Alone in Chemo-Resistant Metastatic Colorectal CancerFrance FranceRecruiting
Evaluation of Regorafenib with Metronomic Cyclophosphamide, Capecitabine, and Low-Dose Aspirin in Second-Line Metastatic Colorectal CarcinomaFrance FranceRecruiting
Evaluation of Spartalizumab, Docetaxel, Cisplatin, and Fluorouracil with Radiotherapy in Metastatic Squamous Cell Anal Carcinoma: A Phase IIA StudyFrance FranceNot Recruiting
Evaluation of UCPVax and Pembrolizumab with Standard Therapy in Adjuvant Treatment of Unmethylated MGMT GlioblastomaFrance FranceNot Yet Recruiting
Evaluation of Vildagliptin for the Prevention of New-Onset Diabetes Mellitus Post-Renal Transplantation in the Early Post-Transplant PeriodFrance FranceRecruiting
Feasibility of Early Dapagliflozin Initiation Versus Standard Care in Elderly Patients Hospitalized for Decompensated Chronic Heart Failure: A Randomized StudyFrance FranceNot Yet Recruiting
Neoadjuvant Pembrolizumab in High-Risk Stage IIB/IIC Cutaneous Melanoma: A Phase IIA Single-Arm Study Assessing Major Pathological ResponseFrance FranceNot Yet Recruiting
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Data & Insights

science
Molecule Portfolio
Compounds under investigation
0
Exclusive Molecules
out of 26 total (0% not shared with other sponsors)

This sponsor works with 26 molecules, of which 0 are not being studied by other sponsors.

hub
Site Partnerships
Collaboration with research centres
47%
Return partnership rate
28 of 60 sites collaborated multiple times

This sponsor has worked with 60 sites across their trial portfolio.

Therapeutic Focus

  • 1.
    Digestive System Diseases7 trials
    280 other sponsors
  • 2.
    Cardiovascular Diseases1 trial
    359 other sponsors
  • 3.
    Immune System Diseases1 trial
    322 other sponsors
  • 4.
    Male Urogenital Diseases1 trial
    111 other sponsors
  • 5.
    Metabolism1 trial
    38 other sponsors
  • 6.
    Neoplasms1 trial
    853 other sponsors
  • 7.
    Nervous System Diseases1 trial
    449 other sponsors
  • 8.
    Not possible to specify1 trial
    220 other sponsors
  • 9.
    Otorhinolaryngologic Diseases1 trial
    49 other sponsors
  • 10.
    Skin and Connective Tissue Diseases1 trial
    247 other sponsors

Partnered Research Centres

60 centres
location_city
assignment966
Assistance Publique Hopitaux De Marseille
Address
264 Rue Saint Pierre, 13005 Marseille
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location_city
assignment478
Assistance Publique Hopitaux De Paris
Address
Num Voie 47 A 83, 47 Boulevard De L Hopital, 75013 Paris
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location_city
assignment444
Besancon University Hospital Center
Address
3 Boulevard Alexandre Fleming, 25000 Besançon
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location_city
assignment366
Centr Georges Francois Leclerc
Address
1 Rue Professeur Marion, 21000 Dijon
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location_city
assignment290
Centre Antoine Lacassagne
Address
33 Avenue De Valombrose, 06189 Nice
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location_city
assignment261
Centre De Lutte Contre Le Cancer Eugene Marquis
Address
Avenue La Bataille Flandre Dunkerque, Cs 44229, 35042 Rennes
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