Cara Therapeutics Inc.
- Address
- 107 Elm Street Fl 9
Sponsor Overview
Specializations
Dermatology and Pruritus
Clinical research is focused on moderate-to-severe itch in adults with notalgia paresthetica, with attention to symptom control and patient discomfort linked to chronic skin-related sensory disturbance.
- Itch intensity
- Chronic pruritus
- Notalgia paresthetica
The sponsor’s current activity centers on therapeutic options for persistent pruritic symptoms in an adult dermatologic population.
Neuropathic Sensory Symptoms
Research interest extends to the sensory manifestations of notalgia paresthetica, particularly the overlap between localized itching and neuropathic discomfort.
- Sensory disturbance
- Localized neuropathic itch
- Adult symptom burden
This area reflects a therapeutic focus on conditions where itch is driven by altered nerve-related signaling rather than purely inflammatory skin disease.
Oral Therapeutics
The clinical program includes interest in oral treatment options for managing persistent itch, with evaluation centered on patient-reported relief and tolerability in an outpatient setting.
- Systemic anti-itch therapy
- Patient-reported outcomes
- Symptom relief
Development activity is directed toward a pharmaceutical approach for a chronic condition with limited established therapeutic choices.
Adult Ambulatory Care
Trials are positioned within an adult outpatient population, supporting research into day-to-day management of persistent itch associated with a chronic sensory disorder.
- Adult patients
- Outpatient management
- Chronic symptom control
The sponsor’s research landscape is concentrated on improving treatment options for adults living with ongoing pruritic symptoms.
Sponsored Trials
| Trial Name | Country | Status |
|---|---|---|
| Evaluation of Oral Difelikefalin Efficacy and Safety in Moderate-to-Severe Pruritus Associated with Notalgia Paresthetica in Adults: A Randomized, Double-Blind Study |  Germany Poland Spain | Not Recruiting |
Data & Insights
This sponsor works with 1 molecule, of which 0 are not being studied by other sponsors.
This sponsor has worked with 18 sites across their trial portfolio.
Therapeutic Focus
- 1.Nervous System Diseases1 trial449 other sponsors
- 2.Skin and Connective Tissue Diseases1 trial247 other sponsors
Partnered Research Centres
18 centres- Address
- Ul. Ul. Ludwika Solskiego 4a/1, 52-416 Wroclaw
- Address
- Ul. Marszalka Jozefa Pilsudskiego 9, 41-200 Sosnowiec
- Address
- Ul. Ul. Sliczna 13, 50-566 Wroclaw
- Address
- Grenadierstrasse 1, Neckarstadt, 68167 Berlin
- Address
- Charlottenstrasse 12/1, 88045 Friedrichshafen
- Address
- Ul. Krzysztofa Kolumba 6, 51-503 Wroclaw
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