Calcilytix Therapeutics Inc.
- Address
- 1800 Owens Street Suite C1200
Sponsor Overview
Specializations
Autosomal Dominant Hypocalcemia Type 1 and calcium homeostasis
Calcilytix Therapeutics Inc. focuses on Autosomal Dominant Hypocalcemia Type 1 (ADH1), a rare disorder affecting calcium regulation and parathyroid hormone signaling. Its clinical activity is centered on correcting abnormalities in blood calcium and urinary calcium excretion.
- Hypocalcemia management
- Parathyroid hormone receptor biology
- Calcium balance
The sponsor’s research interest is concentrated on therapies for inherited disorders of mineral metabolism.
Rare endocrine disorders
The company’s trial portfolio is directed toward a specific endocrine condition with implications for skeletal and renal health. This places its work within the broader field of rare disease medicine, with attention to disorders of mineral ion homeostasis.
- Endocrine genetics
- Mineral metabolism
- Renal calcium handling
Its clinical research is aligned with treatment areas where disruption of calcium signaling leads to persistent biochemical imbalance.
Therapeutic development in ADH1
Calcilytix Therapeutics is engaged in the development of a targeted therapy for patients with ADH1, with interest in outcomes related to serum calcium normalization and reduction of hypercalciuria. The therapeutic emphasis is on disease control in a genetically defined population.
- Targeted endocrine therapy
- Biochemical correction
- Inherited calcium-sensing disorders
Its clinical focus reflects involvement in precision-oriented treatment for a rare metabolic condition.
Clinical research in metabolic and renal outcomes
The sponsor’s active trial work includes evaluation of albumin-corrected blood calcium and 24-hour urinary calcium excretion, key measures relevant to both metabolic and kidney complications in ADH1. This places the research at the intersection of endocrinology and nephrology.
- Biochemical monitoring
- Renal mineral handling
- Endocrine-metabolic biomarkers
Its clinical interests remain focused on disease-relevant physiological measures in a rare calcium disorder.
Sponsored Trials
| Trial Name | Country | Status |
|---|---|---|
| CALIBRATE: A Phase 3, Randomized, Open-Label Study Evaluating the Efficacy and Safety of Encaleret Compared to Standard of Care in Participants with Autosomal Dominant Hypocalcemia Type 1 (ADH1) |  Belgium Czechia Denmark France Italy The Netherlands | Not Recruiting |
Data & Insights
This sponsor works with 5 molecules, of which 1 is not being studied by other sponsors.
This sponsor has worked with 9 sites across their trial portfolio.
Therapeutic Focus
- 1.Nutritional and Metabolic Diseases1 trial211 other sponsors
Partnered Research Centres
9 centres- Address
- Via Paradisa 2, 56124 Pisa
- Address
- 78 Rue Du General Leclerc, 94275 Le Kremlin-Bicetre
- Address
- Dr. Molewaterplein 40, 3015 GD Rotterdam
- Address
- 59 Boulevard Pinel, 69500 Lyon
- Address
- Via Olgettina 60, 20132 Milan
- Address
- Palle Juul-Jensens Boulevard 99, 8200 Aarhus
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