Assistance Publique Hopitaux De Paris

Address
Porte 23, 1 Avenue Claude Vellefaux

Sponsor Overview

assignment
262
sponsored trials
science
351
molecules
location_city
430
research centres
public
14
countries
person_search
2803
investigators

Specializations

Onco-Hematology and Bone Marrow Malignancies

Clinical research includes acute leukemias, multiple myeloma, myelodysplastic syndrome, myelofibrosis, primary CNS lymphoma, and other hematologic malignancies, with strong activity in stem cell transplantation and transplant-related complications.

  • Acute lymphoblastic leukemia
  • Acute myeloid leukemia
  • Multiple myeloma
  • Allogeneic hematopoietic stem cell transplantation
  • Graft-versus-host disease

Research also covers lymphoma, plasma cell leukemia, and post-transplant immune complications in adult and pediatric populations.

Critical Care, Sepsis, and Infectious Diseases

The sponsor is active in intensive care medicine and severe infection management, including septic shock, community-acquired pneumonia, ventilator-associated pneumonia, candidemia, cytomegalovirus infection, and multidrug-resistant bacterial infections.

  • Sepsis
  • Septic shock
  • Ventilator-associated pneumonia
  • Invasive mechanical ventilation
  • Antimicrobial and antiviral treatment

Studies also address post-ICU complications, acute respiratory failure, and infection-related organ dysfunction in both adults and children.

Autoimmune, Inflammatory, and Rheumatologic Diseases

Research spans vasculitis, systemic sclerosis, sarcoidosis, myositis, lupus, rheumatoid-spectrum inflammatory disease, and autoinflammatory syndromes, with a marked focus on immune-mediated organ injury.

  • ANCA-associated vasculitis
  • Takayasu arteritis
  • Systemic sclerosis
  • Inflammatory bowel disease
  • Familial Mediterranean fever

Additional work involves uveitis, cryoglobulinemic vasculitis, Behçet’s disease, and immune thrombocytopenia.

Cardiovascular, Cerebrovascular, and Cardiorenal Disorders

Clinical studies address acute myocardial infarction, heart failure, cardiogenic shock, valvular heart disease, stroke, pulmonary hypertension, and thromboembolic disease, alongside related renal and vascular complications.

  • Myocardial infarction
  • Ischemic stroke
  • Heart failure
  • Pulmonary arterial hypertension
  • Kidney injury and transplant-related disease

Research also includes atrial arrhythmias, aortic and tricuspid valve disease, venous thromboembolism, and renal transplant rejection.

Neurology, Respiratory Medicine, and Perinatal Care

The portfolio includes amyotrophic lateral sclerosis, multiple sclerosis, brain tumors, neurodevelopmental disorders, depression, and pain management, together with asthma, chronic respiratory failure, and severe lung disease.

  • Amyotrophic lateral sclerosis
  • Multiple sclerosis
  • Severe asthma and respiratory insufficiency
  • Major depressive disorder
  • Pregnancy and neonatal complications

Trials also cover infertility, preterm birth, neonatal intensive care, pediatric pain, and neurologic injury in critically ill patients.

Sponsored Trials

Trial Name Country Status
48‑Week Verapamil Hydrochloride to Preserve Beta‑Cell Function in Ages 7–45 With Stage 1 or 2 Type 1 Diabetes – Randomized Placebo‑Controlled TrialFrance FranceNot Yet Recruiting
A Double-Blind Randomized Controlled Trial of Clostridium Botulinum Neurotoxin Type A Injection in Preoperative Management of Large Incisional HerniaFrance FranceRecruiting
A multicenter randomized trial to evaluate the efficacy of pioglitazone to promote renal tolerance in ANCA-associated vasculitis - RENATOFrance FranceRecruiting
A Phase III Multicenter Randomized Trial Comparing Anakinra and Intravenous Immunoglobulin in Kawasaki Disease Patients Unresponsive to Initial IVIG TherapyFrance FranceRecruiting
A Randomized Non-Inferiority Trial of Doxycycline Monohydrate Versus Benzathine Benzylpenicillin for the Treatment of Early SyphilisFrance FranceNot Recruiting
A Randomized, Assessor-Blinded Trial Comparing Lenalidomide and Methotrexate in Patients with Refractory Cutaneous Lupus ErythematosusFrance FranceRecruiting
A Randomized, Double-Blind, Placebo-Controlled Trial Comparing Nicotine-Containing Electronic Cigarettes, Varenicline, and Nicotine-Free Electronic Cigarettes in SmokersFrance FranceNot Yet Recruiting
Adjuvant mitotane vs. mitotane with cisplatin/etoposide after primary surgical resection of localised adrenocortical carcinoma with high risk of recurrence (ADIUVO-2 Trial): A pragmatic, randomised, low-intervention phase III, clinical trial with an observational arm.France FranceGermany GermanySweden SwedenRecruiting
BASECOVID - Bevacizumab in post-acute sequelae of COVID-19 : Efficacy and Safety (Pilot Study)France FranceNot Yet Recruiting
Comparative Efficacy and Safety of Adalimumab Versus Mycophenolate Mofetil in Steroid-Dependent Non-Infectious UveitisFrance FranceRecruiting
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Data & Insights

science
Molecule Portfolio
Compounds under investigation
25
Exclusive Molecules
out of 351 total (7% not shared with other sponsors)

This sponsor works with 351 molecules, of which 25 are not being studied by other sponsors.

hub
Site Partnerships
Collaboration with research centres
48%
Return partnership rate
206 of 430 sites collaborated multiple times

This sponsor has worked with 430 sites across their trial portfolio.

Therapeutic Focus

  • 1.
    Immune System Diseases40 trials
    322 other sponsors
  • 2.
    Cardiovascular Diseases34 trials
    359 other sponsors
  • 3.
    Bacterial Infections and Mycoses31 trials
    180 other sponsors
  • 4.
    Nervous System Diseases24 trials
    449 other sponsors
  • 5.
    Respiratory Tract Diseases22 trials
    277 other sponsors
  • 6.
    Hemic and Lymphatic Diseases21 trials
    249 other sponsors
  • 7.
    Digestive System Diseases20 trials
    280 other sponsors
  • 8.
    Neoplasms19 trials
    853 other sponsors
  • 9.
    Musculoskeletal Diseases13 trials
    238 other sponsors
  • 10.
    Virus Diseases12 trials
    182 other sponsors
  • 11.
    Skin and Connective Tissue Diseases11 trials
    247 other sponsors
  • 12.
    Female Urogenital Diseases and Pregnancy Complications8 trials
    142 other sponsors
  • 13.
    Nutritional and Metabolic Diseases8 trials
    211 other sponsors
  • 14.
    Therapeutics8 trials
    87 other sponsors
  • 15.
    Mental Disorders7 trials
    150 other sponsors
  • 16.
    Pathological Conditions, Signs and Symptoms6 trials
    91 other sponsors
  • 17.
    Congenital, Hereditary, and Neonatal Diseases and Abnormalities5 trials
    165 other sponsors
  • 18.
    Not possible to specify5 trials
    220 other sponsors
  • 19.
    Male Urogenital Diseases4 trials
    111 other sponsors
  • 20.
    Behavior and Behavior Mechanisms3 trials
    38 other sponsors
  • 21.
    Eye Diseases3 trials
    138 other sponsors
  • 22.
    Hormonal diseases3 trials
    89 other sponsors
  • 23.
    Surgical Procedures, Operative3 trials
    58 other sponsors
  • 24.
    Anesthesia and Analgesia2 trials
    100 other sponsors
  • 25.
    Otorhinolaryngologic Diseases2 trials
    49 other sponsors
  • 26.
    Biological Phenomena1 trial
    8 other sponsors
  • 27.
    Digestive System and Oral Physiological Phenomena1 trial
    16 other sponsors
  • 28.
    Genetic Phenomena1 trial
    26 other sponsors
  • 29.
    Musculoskeletal and Neural Physiological Phenomena1 trial
    28 other sponsors
  • 30.
    Physiological processes1 trial
    28 other sponsors
  • 31.
    Psychological Phenomena1 trial
    20 other sponsors

Partnered Research Centres

430 centres
location_city
assignment57
Aix Marseille University
Address
264 Boulevard de Saint Pierre, 13005 Marseille
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location_city
assignment2
Alentis Development
Address
1 Place De L Hopital, 67000 STRASBOURG, Alsace
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location_city
assignment283
Algemeen Ziekenhuis Delta
Address
Deltalaan 1, 8800 Roeselare
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location_city
assignment966
Assistance Publique Hopitaux De Marseille
Address
264 Rue Saint Pierre, 13005 Marseille
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location_city
assignment23
Assistance Publique Hopitaux De Paris
Address
78 Rue Du General Leclerc, 94270 Le Kremlin-Bicetre
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location_city
assignment28
Assistance Publique Hopitaux De Paris
Address
51 Av Du Mal De Lattre De Tassigny, 94000 Créteil
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