Askbio Inc.
- Address
- 20 Tw Alexander Drive Suite 110
Sponsor Overview
Specializations
Neurology and Movement Disorders
Clinical research centers on Parkinson’s disease and Multiple System Atrophy, with attention to long-term safety, tolerability, and therapeutic effect in progressive neurodegenerative conditions.
- Parkinson’s disease
- Multiple System Atrophy
- MSA-P subtype
The portfolio includes work related to gene therapy for central nervous system disorders and delivery into brain regions involved in motor control.
Cardiology and Heart Failure
Research also addresses non-ischemic cardiomyopathy and NYHA Class III congestive heart failure, focusing on cardiac function and symptom burden in advanced heart failure.
- Non-ischemic cardiomyopathy
- Congestive heart failure
- NYHA Class III symptoms
These studies reflect interest in intracoronary delivery approaches for cardiovascular disease.
Gene Therapy and Neurologic Delivery
A major area of activity involves AB-1005 and methods for administering therapeutic material to the putamen and other brain targets, with emphasis on precise neurological delivery.
- Intraputaminal administration
- Convection-enhanced delivery (CED)
- iMRI monitoring
Work in this area is linked to disorders with motor and autonomic involvement, where targeted brain delivery is central to treatment development.
Cardiovascular Gene-Based Therapy
The sponsor is active in gene therapy for cardiomyopathy and heart failure, including research on AB-1002 for patients with advanced symptomatic cardiac disease.
- Intracoronary infusion
- Cardiac gene delivery
- Non-ischemic cardiomyopathy
This area combines cardiology and molecular medicine in the setting of structural heart disease.
Sponsored Trials
| Trial Name | Country | Status |
|---|---|---|
| (ASK-PD0-CS002) Long-Term Safety and Efficacy Follow-up of AB-1005 Gene Transfer Study Participants with Parkinson’s Disease or Multiple System Atrophy |  Poland | Not Yet Recruiting |
| A study to improve the delivery of AAV2-GDNF and gadoteridol into the brain for patients with Parkinson's disease | Poland | Not Yet Recruiting |
| Evaluation of Intracoronary AB-1002 Efficacy and Safety in NYHA Class III Non-Ischemic Cardiomyopathy |  Austria Belgium Bulgaria Germany Hungary Poland Romania Spain The Netherlands | Not Recruiting |
Data & Insights
This sponsor works with 5 molecules, of which 2 are not being studied by other sponsors.
This sponsor has worked with 54 sites across their trial portfolio.
Therapeutic Focus
- 1.Nervous System Diseases2 trials449 other sponsors
- 2.Cardiovascular Diseases1 trial359 other sponsors
Partnered Research Centres
54 centres- Address
- Ul. Aleje Raclawickie 23, 20-049 Lublin
- Address
- Bulevard Nikola Yonkov Vaptsarov 51b, 1407 Sofia
- Address
- Deltalaan 1, 8800 Roeselare
- Address
- Ul. Franklina Delano Roosevelta 2, 47-200 Kedzierzyn-Kozle
- Address
- De Boelelaan 1117, 1081 HV Amsterdam
- Address
- Carrer De La Feixa Llarga S/N, 08907 L'hospitalet De Llobregat
Want to get in touch with this sponsor?
Send a question and we'll pass it on to Askbio Inc..
Need a custom report on this sponsor?
Competitive positioning, market entry, partnership opportunities — tell us the question.
Is something out of date?
Tell us what needs correcting and we'll update this profile.