Annexon Inc.
- Address
- 1400 Sierra Point Parkway
Sponsor Overview
Specializations
Retinal Disease and Geographic Atrophy
Annexon Inc. is active in dry age-related macular degeneration with geographic atrophy, focusing on visual function, visual acuity, and the preservation of retinal integrity.
- Dry age-related macular degeneration
- Geographic atrophy
- Visual acuity
- Intravitreal therapy
The sponsor’s ophthalmic research reflects interest in retina-targeted treatment for progressive degenerative eye disease.
Autoimmune Hematology and Cold Agglutinin Disease
Annexon Inc. also studies primary cold agglutinin disease, a rare autoimmune hemolytic disorder marked by complement-driven red blood cell destruction and related hematologic complications.
- Primary cold agglutinin disease
- Autoimmune hemolytic anemia
- Complement-mediated disease
- Hematology
This area of work places emphasis on immune dysregulation and blood-related disease mechanisms.
Complement Biology
The sponsor’s clinical portfolio is centered on complement pathway modulation, spanning both ocular and hematologic conditions linked to inflammatory tissue injury.
- Complement inhibition
- Inflammatory injury
- Immune-mediated pathology
Research activity in this domain connects innate immunity with disease-specific therapeutic development.
Sponsored Trials
| Trial Name | Country | Status |
|---|---|---|
| An Open-Label Study to Evaluate the Pharmacokinetics, Pharmacodynamics, Efficacy, and Safety of a Single Dose of ANX005 in Participants With Guillain-Barré Syndrome |  Denmark France Spain | Recruiting |
| Efficacy and Safety of Intravitreal ANX007 in Geographic Atrophy Secondary to Age-Related Macular Degeneration: A Phase 3 Randomized Controlled Trial |  Austria Czechia France Germany Hungary Italy Poland Spain The Netherlands | Not Recruiting |
| Safety, Tolerability, and Pharmacokinetics of ANX1502 in Primary Cold Agglutinin Disease: A Phase 1b, Open-Label, Single-Arm Study | Austria | Not Recruiting |
Data & Insights
This sponsor works with 2 molecules, of which 2 are not being studied by other sponsors.
This sponsor has worked with 56 sites across their trial portfolio.
Therapeutic Focus
- 1.Immune System Diseases2 trials322 other sponsors
- 2.Eye Diseases1 trial138 other sponsors
- 3.Musculoskeletal Diseases1 trial238 other sponsors
Partnered Research Centres
56 centres- Address
- Palle Juul-Jensens Boulevard 99, 8200 Aarhus
- Address
- Via Giovanni Battista Grassi 74, 20157 Milan
- Address
- Hohenzollernring 74, Herz-Jesu, 48145 Munster
- Address
- Ostrovskeho 253/3, Smichov, 150 00 Prague
- Address
- Largo Giovanni Alessandro Brambilla 3, 50134 Florence
- Address
- Maglodi Ut 89-91, Kerulet, 1106 Budapest
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