Angelini Pharma Italia Aziende Chimiche Riunite Angelini Francesc O A.C.R.A.F. S.p.A.

Address: Viale Amelia 70

Sponsor Overview

assignment

Specializations

Psychiatry and mood disorders

Clinical research includes major depressive disorder with and without anxiety, with interest in treatments used in mental health care.

Trazodone hydrochloride
Depressive symptoms
Anxiety features

The sponsor’s work in this area is centered on therapeutic options for depression and related psychiatric conditions.

Otolaryngology and upper respiratory tract inflammation

Research activity also covers non-streptococcal pharyngotonsillitis, with attention to symptom relief in throat inflammation and oropharyngeal pain.

Pharyngotonsillitis
Throat pain
Inflammatory discomfort

This area reflects interest in treatments for acute ENT conditions affecting the pharynx and tonsils.

Analgesia and symptom control

The sponsor funds studies focused on pain relief, particularly for localized mucosal and throat-related pain in pediatric and adult settings.

WBFPRS pain assessment
Localized analgesic effect
Oral symptom relief

These studies place emphasis on patient-reported outcomes linked to analgesic benefit.

Clinical pharmacology and bioavailability

Research also includes pharmacokinetic evaluation of trazodone formulations, with interest in how different oral tablets compare in systemic exposure.

Bioavailability
Oral formulation performance
Steady-state exposure

This domain connects the sponsor’s psychiatric portfolio with drug formulation assessment.

Paediatric therapeutic research

Part of the sponsor’s clinical landscape involves children aged 6 to 11 years, with studies addressing paediatric management of pharyngotonsillitis and associated discomfort.

Children’s health
Oral lozenge treatment
Throat symptom relief

This indicates involvement in age-specific care for acute inflammatory conditions of the upper airway.

Trial Name	Country	Status
Bioavailability Comparison of Trazodone Hydrochloride Tablets in Major Depressive Disorder with and without Anxiety: A Randomized, Crossover Study	Germany	Not Recruiting
Phase IV Open‑Label Study of Trazodone Hydrochloride for Emotional Blunting in Major Depressive Disorder Patients with Inadequate Response to Prior SSRI/SNRI Therapy	Bulgaria Hungary Poland	Not Yet Recruiting
Phase IV Study of Benzydamine Hydrochloride Lozenges for Pain Relief in Pediatric Non-Streptococcal Pharyngotonsillitis	Italy	Not Yet Recruiting
Randomized, Double‑Blind, Placebo‑Controlled, Multiple‑Dose Study of CV‑01: Safety, Tolerability, PK/PD in Healthy Subjects and Drug‑Resistant Epilepsy	Sweden	Not Yet Recruiting