Amsterdam UMC Stichting

The sponsor supports studies in inflammatory bowel disease, including Crohn's disease and ulcerative colitis, as well as rheumatoid arthritis, systemic lupus erythematodes, lupus nephritis, multiple sclerosis, psoriasis, atopic eczema, and chronic rhinosinusitis with nasal polyps. It also investigates fibrotic and immune-mediated conditions affecting the lungs, kidneys, and other organs.

• Crohn’s disease and ulcerative colitis
• Lupus nephritis and systemic lupus erythematodes
• Multiple sclerosis and inflammatory myopathy
• Psoriasis and atopic eczema
• Fibrosis in gut, lung, and kidney disease

Work in this area includes immune modulation, tissue inflammation, and organ-specific fibrotic change.

Amsterdam UMC is active in Alzheimer's disease, dementia, mild cognitive impairment, Parkinson's disease, post-traumatic stress disorder, insomnia, and major depressive disorder. Its portfolio also includes rare neurological and neuromuscular disorders such as vanishing white matter, fragile X syndrome, tuberous sclerosis complex, Sanfilippo syndrome, Gaucher disease type 3, and multiple sclerosis.

• Alzheimer’s disease and dementia
• Parkinson’s disease
• Multiple sclerosis
• Rare neurogenetic syndromes
• Psychiatric and sleep-related disorders

Research also covers symptom control, neuroimaging, and functional outcomes in neurological disease.

The sponsor funds research in acute coronary syndrome, myocardial infarction, atrial fibrillation, coronary artery disease, aortic valve stenosis, pulmonary arterial hypertension, vasospastic angina, and stroke. It also studies type 2 diabetes, diabetes mellitus, obesity, kidney failure, acute kidney injury, kidney transplantation, and lupus nephritis.

• Coronary and rhythm disorders
• Stroke and vascular disease
• Diabetes and metabolic regulation
• Kidney failure and transplantation
• Pulmonary hypertension

Clinical work in this domain includes cardiovascular risk, haemodynamic disease, and renal protection.

Amsterdam UMC shows active interest in menopause, climacteric symptoms, polycystic ovary syndrome, infertility, uterine fibroids, placenta previa, preterm birth, preterm preeclampsia, and other hypertensive disorders of pregnancy. Its research also includes reproductive and hormonal health in transgender women receiving gender-affirming hormone therapy.

• Menopause and climacteric symptoms
• Infertility and polycystic ovary syndrome
• Pregnancy complications
• Uterine and placental disorders
• Gender-affirming hormone therapy

Studies in this area address endocrine balance, maternal-fetal health, and reproductive function.